At present there remains a lack of information on the prevalence of emerging campylobacteriaceae in the epidemiology of gastro-enteritis worldwide. Until formal studies are established using methods capable of isolating and identifying these bacteria, the extent of their clinical relevance will remain an unknown. Even when the clinical picture has been addressed, there is hardly any information on the environmental or animal reservoirs that harbour these new campylobacteriaceae. Indeed the approved isolation procedures across Europe and elsewhere are designed to primarily isolate thermo-tolerant Campylobacter spp. such as C. jejuni and C. coli and are known not to isolate these emerging campylobacteriaceae.
Therefore, this project involves leading laboratories from the EU, USA and South Africa for the isolation and immunological and molecular identification of emerging campylobacteriaceae in patient and animal faeces and the food and water chain.
The global objective of this project is to develop improved physiological, immunological and molecular tools for the recovery of emerging campylobacteriaceae in the food and water chain and communicate the risk exposure to stakeholders. This information will enable stakeholders to formulate their own risk management strategies.
- Development of quantitative resuscitation and culture techniques to detect emerging campylobacteriaceae of clinical and veterinary importance
- Establishment of culture collection and DNA bank
- Development of sensitive antibodies for ELISA and dipstick detection, and latex identification
- Development of complementary molecular and biochemical techniques for identification and typing
- National surveys to characterise prevalence of campylobacteriaceae in human and animal faeces, and in the food and water chains
- Determination of the quantitative risk exposure of these new species throughout the food chain
- Communication of the risk exposure to stakeholders, including a workshop