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Development of rapid easy-to-use immunochemical tests
for the detection of proteins with allergenic potential in food
ALLERGENTEST

Contract number : QLK1-2001-01151
Contract type : Shared Cost Project
Total cost : € 1.453.238
EC contribution : € 1.010.761
Starting date : not yet determined
Duration : 42 Months
Scientific Officer : Barend Verachtert
Project website : not yet available
Dr Rudolf Krska
Interuniversitäres Forschungsinstitut für Agrarbiotechnologie
Analytikzentrum
Konrad-Lorenz-Straße 20
3430 Tulln
Austria
Tel.: +43227266280401
Fax: +43227266280403
E-mail: krska @ ifa-tulln.ac.at
Background

Allergenic proteins, such as peanut and hazelnut protein in certain food might cause severe adverse reactions in allergic patients. Rapid and easy-to-use methods are demanded if contaminated food products should be surveyed on the market. The major goal of this project is the development of rapid easy-to-use immunochemical tests for the detection of these proteins in food. The test format should allow the detection of the soluble proteins of hazelnut or peanut ("protein-assay"). In addition, for some selected allergenic protein fractions of peanut and hazelnut, specific assays ("allergen-assay") will be developed for the detection of a certain allergen. In-vitro cellular analysis will be carried out to assess the stimulatory activity of trace amounts of these proteins in order to obtain better information on the required sensitivity of the novel assay. In addition, the dissemination of the project results is an important element of this project.

Objectives

The presence of allergenic proteins, such as peanut and hazelnut proteins, in certain food might cause severe adverse reactions in allergic patients. Even traces can result in fatal reactions. Among food allergy, peanut and hazelnut allergy is common and severe. As the only effective measure for these individuals is avoidance of the offending foods, powerful analytical methods are required for the screening of trace amounts of potentially allergenic proteins in food samples. Rapid and easy-to-use methods are demanded if contaminated food products should be surveyed on the market. The major goal of this project is the development of rapid easy-to-use immunochemical tests for the detection of hidden proteins with allergenic potential in food. The developed tests are intended to be used as a diagnostic tool to avoid contamination and to check uncertain food.


Partners

State Institute For Quality Control of Agricultural Products
Natural Constituents, Residues and Contaminants
Bornsesteeg 45, PO Box 230
6708 PD Wageningen
The Netherlands
Ministry of Agriculture
Fisheries & Food Plant Health Group
Central Science Laboratory
Sand Hutton
YO41 LlZ York
United Kingdom
Technische Universität München
Institut für Wasserchemie und Chemische Balneologie
Marchioninistraße 17
81377 München
Germany
R-Biopharm GmbH
Dolivostraße 10
64293 Darmstadt
Germany
Università degli Studi di Milano
Istituto di Scienze Farmacologiche
Via Balzaretti 9
20133 Milano
Italy
Verbruikersunie Test-Aankoop S .V.
Hollandstraat 13
1060 Brussel
Belgium
Central Manchester Healthcare
NHS Trust Regional Immunology Department
St Mary's Hospital
Hathersage Road
M13 0TH Manchester
United Kingdom


Fifth Framework Programme

PDF Version

:

Volume 1 (PDF 2.9 MB)

   

Volume 2 (PDF 1.9 MB)

 

Last update

:

23-09-2003



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