TOPIC : A vaccine against African swine fever
|Publication date:||27 October 2017|
|Types of action:||IA Innovation action|
|DeadlineModel: Planned opening date:||single-stage 16 October 2018||Deadline:||23 January 2019 17:00:00|
|Time Zone : (Brussels time)|
Topic DescriptionSpecific Challenge:
African swine fever (ASF) is a devastating viral disease of swine which is endemic in Africa and has been present in Europe for several years, after its introduction from Trans-Caucasian countries. It is a transmissible disease that has the potential for very serious and rapid spread, irrespective of national borders. It has a serious socio-economic impact on farming sector and is of major importance in the international trade of animals and animal products. While in the EU, strict control measures including in particular biosecurity, culling of infected pigs, killing of wild-boars, have so far managed to contain the spread of the disease, restrictions on farming and trade remain. The threat is permanent (including incursion of exotic strains from endemic countries) and concerns are raised on the possibility to eradicate the disease without vaccination.
No vaccine is currently available and the development of effective and safe ASF vaccines is urgent as an additional tool to re-inforce control and eradication strategies currently in place. For details of potential strategies and possible research steps for vaccine development, see the blueprint and roadmap produced by the EU Reference Laboratory for ASF.Scope:
The research proposals will address the necessary steps for developing safe vaccines against ASF for domestic pigs and wild boars. Proposals should build on past or ongoing EU funded research and on current knowledge of the characteristics of the viruses and research gaps, with the overall purpose of developing pilot vaccines and their companion DIVA test. Activities should address vaccination as part of a control strategy in different scenarios and should consider the potential impact on animal production and trade. Particular focus should be put on the European situation and the role of wild boars in the spread of the disease, so the proposals should address at least the ASF viruses circulating in Europe, and may also cover all or the most relevant exotic ones. Wild fauna other than wild boars, that are involved in the epidemiology and for which vaccination may help control the disease, may also be addressed. Participation by non-EU regions particularly affected by ASF is recommended.
The selected project should take into consideration the EU animal health regulatory framework, and follow the policies and contribute to the objectives of the STAR-IDAZ international research consortium.
Proposals should fall under the concept of the 'multi-actor approach' and be based on the active participation of stakeholders from research, animal health authorities and the farming and business sectors. Involvement of the pharmaceutical industry is highly recommended.
The Commission considers that proposals requesting a contribution from the EU of up to EUR 10 million would allow this specific challenge to be addressed appropriately. Nonetheless, this does not preclude the submission and selection of proposals requesting other amounts.Expected Impact:
- Pilot ASF vaccines and their companion DIVA tests for the possible prevention and/or eradication of the disease in domestic pigs and wild boars, at target TRL 5-6;
- Contribution to international cooperation on animal health research, potentially reducing the threats from the introduction of exotic ASF virus strains in the EU and reducing the burden of ASF in countries outside the EU.
More generally, the selected project will contribute to a reduction of economic losses by the farming sectors and contribute to healthy livestock production. It will contribute to reduce the sanitary barriers to trade in swine and products therefrom.Cross-cutting Priorities:
See definition of the 'multi-actor approach' in the introduction to this Work Programme part.
Topic conditions and documents
1. Eligible countries: described in Annex A of the Work Programme.
A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon 2020 projects. See the information in the Online Manual.
Proposal page limits and layout: please refer to Part B of the proposal template in the submission system below.
- Evaluation criteria, scoring and thresholds are described in Annex H of the Work Programme.
- Submission and evaluation processes are described in the Online Manual.
4. Indicative time for evaluation and grant agreements:
Information on the outcome of evaluation (single-stage call): maximum 5 months from the deadline for submission.
Signature of grant agreements: maximum 8 months from the deadline for submission.
5. Proposal templates, evaluation forms and model grant agreements (MGA):
6. Additional provisions:
Members of consortium are required to conclude a consortium agreement, in principle prior to the signature of the grant agreement.
8. Additional documents:
1. Introduction WP 2018-20
9. Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy WP 2018-20
18. Dissemination, Exploitation and Evaluation WP 2018-20
7. Open access must be granted to all scientific publications resulting from Horizon 2020 actions.
Where relevant, proposals should also provide information on how the participants will manage the research data generated and/or collected during the project, such as details on what types of data the project will generate, whether and how this data will be exploited or made accessible for verification and re-use, and how it will be curated and preserved.
Open access to research data
The Open Research Data Pilot has been extended to cover all Horizon 2020 topics for which the submission is opened on 26 July 2016 or later. Projects funded under this topic will therefore by default provide open access to the research data they generate, except if they decide to opt-out under the conditions described in Annex L of the Work Programme. Projects can opt-out at any stage, that is both before and after the grant signature.
Note that the evaluation phase proposals will not be evaluated more favourably because they plan to open or share their data, and will not be penalised for opting out.
Open research data sharing applies to the data needed to validate the results presented in scientific publications. Additionally, projects can choose to make other data available open access and need to describe their approach in a Data Management Plan.
Projects need to create a Data Management Plan (DMP), except if they opt-out of making their research data open access. A first version of the DMP must be provided as an early deliverable within six months of the project and should be updated during the project as appropriate. The Commission already provides guidance documents, including a template for DMPs. See the Online Manual.
Eligibility of costs: costs related to data management and data sharing are eligible for reimbursement during the project duration.
The legal requirements for projects participating in this pilot are in the article 29.3 of the Model Grant Agreement.
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The submission system is planned to be opened on the date stated on the topic header.
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