TOPIC : New Plant Breeding Techniques (NPBT) in molecular farming: Multipurpose crops for industrial bioproducts
|Publication date:||14 October 2015|
|Types of action:||RIA Research and Innovation action|
|DeadlineModel: Planned opening date:||two-stage 11 May 2016||Deadline: 2nd stage Deadline:||
27 October 2016 17:00:00
04 May 2017 17:00:00
|Time Zone : (Brussels time)|
Topic DescriptionSpecific Challenge:
Molecular farming involves the production of pharmaceutical and industrial compounds in plants through advanced technologies and it offers a competitive platform for the manufacturing of high-end products. Examples are plant-derived vaccines and the production of other commercially valuable proteins or small molecules. Indeed, plants are highly amenable to the production of a wide range of proteins, some of which are specific. In addition, the scalability allowed by plants exceeds that of other production systems. Molecular farming represents a development opportunity for a set of new high-value crops, for the health, chemical and agricultural industries and their related technology sectors. However, the expansion of molecular farming has been dawdling, due to its reliance on standard genetic modification and the hurdles it poses for commercialisation.
In the past ten years, complementary and more sophisticated new plant breeding techniques (NPBT) have been developed to produce new plants with the desired traits circumventing the main drawbacks of standard genetic modification (i.e. no foreign DNA is contained in the resulting end product). The use of NPBT for molecular farming could provide opportunities for new crops for the production of bioproducts, while maintaining the position of leadership of the European plant breeding sector in research and innovation.Scope:
Proposals should use the technologies comprised in the NPBT set , in particular those that avoid final genetic modification products, with plants amenable to be used as green factories in order to yield industrial high-value products. Proposals should address at least one of the following areas:
- Minor, underutilized and non-food crops suitable for the extraction of bioactive compounds.
- Crops that grow more efficiently and have higher yields of the target bioproduct, while being more tolerant to adverse environmental conditions.
- Improved plant-based low-cost platforms for commercial production of bioproducts.
Proposals should address elements of Social Sciences and Humanities (SSH), contributing to a better understanding of plant breeding and related biotechnologies by the general public.
Activities are expected to focus on Technology Readiness Levels 3 to 5.
Insofar as possible, proposals will involve SMEs and engage in international cooperation.
The Commission considers that proposals requesting a contribution from the EU between EUR 5 and 7 million would allow this specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts.Expected Impact:
- Contribution to the EU goals of increased sustainability of agriculture and the bio-based economy by developing new types of useful crops.
- New data for the assessment of innovative NBPT as tools for future plant breeding and their potential for a speedy uptake in general breeding practice
- Innovation in the way plant breeding technologies is presented to the public for an improved understanding of biotechnology and informed decision making
Proposals should include a business case and exploitation strategy, as outlined in the Introduction to the LEIT part of this Work Programme.
Topic conditions and documents
Please read carefully all provisions below before the preparation of your application.
- LIST OF COUNTRIES and APPLICABLE RULES FOR FUNDING
described in part A of the General Annexes of the General Work Programme.
Note also that a number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon 2020 projects (follow the links to China, Japan, Republic of Korea, Mexico, Russia, Taiwan).
- ELIGIBILITY and ADMISSIBILITY CONDITIONS
described in part B and C of the General Annexes of the General Work Programme.
Proposal page limits and layout: Please refer to Part B of the standard proposal template.
3.1 Evaluation criteria and procedure, scoring and threshold: described in part H of the General Annexes of the General Work Programme , with the following exceptions:
For single-stage and second-stage evaluations, the threshold for the criteria Excellence and Impact will be 4.
The overall threshold, applying to the sum of the three individual scores, will be 12.
In case of equal overall scores in the ranked list, the priority order of proposals will be established in accordance with part H of the General Annexes, except that proposals will be ranked on the basis of individual scores for the Impact criterion before the Excellence criterion.
In case of equal overall scores in the ranked list, the priority order of proposals will be established in accordance with part H of the General Annexes, except, when comparing ex aequo proposals of different topics, the proposals will be ranked first according to the position in the topic ranked lists
3.2 Submission and evaluation process: Guide to the submission and evaluation process
- INDICATIVE TIMETABLE for EVALUATION and GRANT AGREEMENT
Information on the outcome of two-stage evaluation:
For stage 1: maximum 3 months from the deadline for submission.
For stage 2: maximum 5 months from the deadline for submission.
Signature of grant agreements: maximum 8 months from the deadline for submission.
- PROVISIONS, PROPOSAL TEMPLATES and EVALUATION FORMS
for the type of action under this topic
Research and Innovation Action:
Specific provisions and funding rates
Standard proposal template
Standard evaluation form
H2020 General MGA -Multi-Beneficiary
Annotated Grant Agreement
- ADDITIONAL PROVISIONS
Horizon 2020 budget flexibility
Technology readiness levels (TRL) – where a topic description refers to TRL, these definitions apply.
Financial support to Third Parties – where a topic description foresees financial support to Third Parties, these provisions apply.
- OPEN ACCESS
must be granted to all scientific publications resulting from Horizon 2020 actions, and proposals must refer to measures envisaged.
Where relevant, proposals should also provide information on how the participants will manage the research data generated and/or collected during the project, such as details on what types of data the project will generate, whether and how this data will be exploited or made accessible for verification and re-use, and how it will be curated and preserved.
- ADDITIONAL DOCUMENTS
Legal basis: Horizon 2020 - Regulation of Establishment
Legal basis: Horizon 2020 Rules for Participation
Legal basis: Horizon 2020 Specific Programme
H2020 Work Programme 2016-17: Introduction
H2020 Work Programme 2016-17: Introduction to Leadership in enabling and industrial technologies (LEITs)
H2020 Work Programme 2016-17: Nanotechnologies, advanced materials, advanced manufacturing and processing, biotechnology
H2020 Work Programme 2016-17: Cross-cutting activities (Focus Areas)
H2020 Work Programme 2016-17: Dissemination, Exploitation and Evaluation
H2020 Work Programme 2016-17: General Annexes
The H2020 Work Programme 2016-17 is currently under revision.
An updated version is expected to be published by late July 2016.
The submission service will be opened as soon as the updated version of the H2020 Work Programme 2016-17 is published.
Please consult the updated version of the Work Programme when preparing your proposal.
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