Advanced molecular technique boosts cancer research

After cardiovascular diseases, cancer is the second leading cause of death and morbidity in European countries and is one of the most significant health challenges worldwide. An EU-funded project is developing new tools for diagnosing cancer and for understanding the role of proteins in this and other major diseases.

Countries
Countries
  Algeria
  Argentina
  Australia
  Austria
  Bangladesh
  Belarus
  Belgium
  Benin
  Bolivia
  Bosnia and Herzegovina
  Brazil
  Bulgaria
  Burkina Faso
  Cambodia
  Cameroon
  Canada
  Cape Verde
  Chile
  China
  Colombia
  Costa Rica
  Croatia
  Cyprus
  Czechia
  Denmark
  Ecuador
  Egypt
  Estonia
  Ethiopia
  Faroe Islands
  Finland
  France
  French Polynesia
  Georgia

Countries
Countries
  Algeria
  Argentina
  Australia
  Austria
  Bangladesh
  Belarus
  Belgium
  Benin
  Bolivia
  Bosnia and Herzegovina
  Brazil
  Bulgaria
  Burkina Faso
  Cambodia
  Cameroon
  Canada
  Cape Verde
  Chile
  China
  Colombia
  Costa Rica
  Croatia
  Cyprus
  Czechia
  Denmark
  Ecuador
  Egypt
  Estonia
  Ethiopia
  Faroe Islands
  Finland
  France
  French Polynesia
  Georgia


  Infocentre

Published: 14 March 2019  
Related theme(s) and subtheme(s)
Health & life sciencesBiotechnology  |  Drugs & drug processes  |  Major diseases  |  Medical research
Innovation
International cooperation
Research policyHorizon 2020
Countries involved in the project described in the article
Denmark  |  Germany  |  Norway  |  Sweden  |  United Kingdom
Add to PDF "basket"

Advanced molecular technique boosts cancer research

Image

© Alexander Raths #49399692, 2019 source: stock.adobe.com

Proteins are the basis of cellular and physiological functioning in living organisms. The physical and chemical properties of proteins determine how they act and work within cells. Therefore, the analysis of protein abnormalities is particularly important for the study of heart disease, neurodegenerative diseases, diabetes and cancer.

The objective of the EU-funded BIOCAPTURE project is twofold. First, project researchers are developing novel, robust tests for protein-based biomarkers associated with cancer. Second, they are researching and producing innovative tools that can reveal elusive cancer-related modifications in proteins.

To advance its aims, the BIOCAPTURE team is exploiting molecularly imprinted polymers (MIPs). These are special materials in which researchers create uniquely shaped microscopic cavities which have an affinity for a particular molecule.

Protein sequence-specific MIPs are being used in combination with leading-edge technologies such as mass spectrometry and fluorescence-based detection. This enables BIOCAPTURE project scientists to test for the presence and characteristics of key cancer-related proteins and protein-based structures.

The results of the BIOCAPTURE project will have a major impact on healthcare, leading to new methods for earlier, more reliable diagnosis of diseases, including cancer. The ability to more rapidly identify biomarkers will be very significant in discovering new drugs. Finally, the ability to detect and assess protein modifications will be invaluable in numerous biochemical and medical applications.

The project represents a very exciting interdisciplinary training programme. Eleven early-stage researchers working on specific tasks within five work packages are following a rich training programme, accruing a well-balanced spectrum of scientific, business and entrepreneurial skills.

Together, the activities of the BIOCAPTURE consortium are set to improve cancer treatment standards in Europe, while providing significant economic benefits within the European biotechnology and pharmaceutical sectors.

Project details

  • Project acronym: BIOCAPTURE
  • Participants: Sweden (Coordinator), UK, Germany, Denmark, Norway, South Africa, Italy
  • Project N°: 722171
  • Total costs: € 2 982 879
  • EU contribution: € 2 982 879
  • Duration: November 2016 to October 2020

See also

 

Convert article(s) to PDF

No article selected


loading


Search articles

Notes:
To restrict search results to articles in the Information Centre, i.e. this site, use this search box rather than the one at the top of the page.

After searching, you can expand the results to include the whole Research and Innovation web site, or another section of it, or all Europa, afterwards without searching again.

Please note that new content may take a few days to be indexed by the search engine and therefore to appear in the results.

Print Version
Share this article
See also
Project details