Could nanotechnoloy 'rewire' an injured spinal cord?

Innovative equipment has been developed to help patients regain control of limbs despite an injury that stops the transmission of signals through the spinal cord. But what if this transmission could actually be re-established? An EU-funded project is working on an innovative implant, but there is still a very long way to go.

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Countries
Countries
  Algeria
  Argentina
  Australia
  Austria
  Bangladesh
  Belarus
  Belgium
  Benin
  Bolivia
  Bosnia and Herzegovina
  Brazil
  Bulgaria
  Burkina Faso
  Cambodia
  Cameroon
  Canada
  Cape Verde
  Chile
  China
  Colombia
  Costa Rica
  Croatia
  Cyprus
  Czechia
  Denmark
  Ecuador
  Egypt
  Estonia
  Ethiopia
  Faroe Islands
  Finland
  France
  French Polynesia
  Georgia


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Published: 24 July 2018  
Related theme(s) and subtheme(s)
European Innovation Council (EIC) pilotEIC Accelerator Pilot  |  EIC Pathfinder Pilot
Health & life sciencesMedical research  |  Neuroscience
Information societyMicroelectronics and nanotechnology
Innovation
NanotechnologyNanomedicine
Research policyHorizon 2020
Countries involved in the project described in the article
France  |  Germany  |  Italy  |  Spain
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Could nanotechnoloy 'rewire' an injured spinal cord?

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© okrasyuk #159125776, source: fotolia.com 2018

The BYAXON project makes no extravagant claims. It is very early days for the technology it is proposing, and much more research is needed to take the innovation forward once this four-year undertaking ends in December 2020.

Nonetheless, the project is shaping what might, eventually, turn out to be a major breakthrough in the treatment of paralysis. The partners are developing a prototype of an implant designed to restore signal transmission directly in the spinal cord.

This possibility does not currently exist, they note, adding that the implant would serve as an active local bypass. It would bridge the lesion, reconnecting nerves on either side.

The implant envisaged by BYAXON would enable signals to travel both ways – in addition to instructions reaching the limbs, sensory information would once again be returned to the brain. Current neural interfacing technology does not deliver this feedback, the researchers explain, and typically involves cables or electrodes – or equipment that is not portable.

BYAXON’s innovative approach to neural interfacing involves the development of a new generation of sensors and electrodes based on nanostructured materials. While its research focuses on spinal cord injuries, the partners observe that the technology could be harnessed for other types of neural interface.

Examples include retinal implants, brain-recording systems for people with epilepsy, and deep-brain stimulation devices for the treatment of Parkinson’s disease. BYAXON is backed by a Horizon 2020’s Future and Emerging Technologies (FET) programme, through a grant scheme designed to support the initial stages of research exploring radically new ideas (FET-Open).

Project details

  • Project acronym: BYAXON
  • Participants: Spain (Coordinator), Italy, France, Germany
  • Project N°: 737116
  • Total costs: € 3 752 057
  • EU contribution: € 3 752 057
  • Duration: January 2017 to December 2020

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