Navigation path

Themes
Agriculture & food
Energy
Environment
ERA-NET
Health & life sciences
Human resources & mobility
Industrial research
Information society
Innovation
International cooperation
Nanotechnology
Pure sciences
Research infrastructures
Research policy
Science & business
Science in society
Security
SMEs
Social sciences and humanities
Space
Special Collections
Transport

Countries
Countries
  Argentina
  Australia
  Austria
  Belarus
  Belgium
  Benin
  Brazil
  Bulgaria
  Cameroon
  Canada
  Chile
  China
  Colombia
  Croatia
  Cyprus
  Czech Republic
  Denmark
  Egypt
  Estonia
  Finland
  France
  Georgia
  Germany
  Ghana
  Greece
  Hungary
  Iceland
  India
  Ireland
  Israel
  Italy
  Japan
  Kazakhstan
  Kenya
  Korea
  Latvia
  Lithuania
  Luxembourg
  Macedonia - former Yugoslav Republic
  Malta
  Mexico
  Montenegro
  Morocco
  Namibia
  Netherlands
  Nigeria
  Norway
  Peru
  Poland
  Portugal
  Romania
  Russia
  Senegal
  Serbia
  Slovakia
  Slovenia
  South Africa
  Spain
  Swaziland
  Sweden
  Switzerland
  Taiwan
  Tunisia
  Turkey
  Ukraine
  United Kingdom
  United States


   Infocentre

Last Update: 02-06-2014  
Related category(ies):
Innovation  |  Health & life sciences

 

Countries involved in the project described in the article:
Belgium  |  Denmark  |  France  |  Germany  |  Sweden
Add to PDF "basket"

100,000 peptides on a microscope slide

Proteins, which are present in every cell and tissue of the human body, play a significant role in human health. They are composed of amino acids linked together chemically, and the shorter stretches of amino acids are commonly referred to as peptides. In the body, peptides regulate the activity of many systems. Some peptides act as hormones, others as neurotransmitters, yet others as natural pain relievers.

Illustration of human cells

© Almalm fotolia

Synthetic peptides are now easy to reproduce and are increasingly being used by European scientists to identify or mimic molecules that are the focus of biological research. However, the cost of synthesising them is still a significant barrier to progress in research.

The European Union (EU)-funded PEPCHIPOMICS project has developed a new technology which synthesises and analyses peptides in hundreds of thousands on a single microscope slide.

“The research team developed an innovative peptide ‘chip’ technology platform,” says project director, Professor Søren Buus of the University of Copenhagen, Denmark. “This allows more than one million different peptides to be synthesised on a surface the size of a postage stamp,” he adds.

“The innovative technology we developed significantly multiplies the number of peptides that can be handled and the range of concrete applications,” comments Dr. Claus Schafer-Nielsen, chief executive of Schafer-N, the Danish private-sector research organisation that worked with the PEPCHIPOMICS team.

These synthetic peptides are now being used for developing new vaccines, analysing the reactions of patients to infections from viruses, bacteria and parasites, and detecting traces of allergens – peanuts, hazel nuts and so on – in processed foods.

“The new technology not only increases the amount and quality of the information obtained, but also reduces the price per peptide by a factor of as much as 10,000,” concludes Dr. Schafer-Nielsen. The technology is expected to help the scientific community conduct further large-scale investigations into the overall functions and effects of proteins and peptides.

 

Project details

  • Project acronym: PEPCHIPOMICS
  • Participants:Denmark (Coordinator), Germany, France, Belgium, Sweden
  • Project FP7 222773
  • Total costs: € 3 837 556
  • EU contribution: € 2 939 065
  • Duration: October 2008 - March 2012

Convert article(s) to PDF

No article selected


loading


Search articles

Notes:
To restrict search results to articles in the Information Centre, i.e. this site, use this search box rather than the one at the top of the page.

After searching, you can expand the results to include the whole Research and Innovation web site, or another section of it, or all Europa, afterwards without searching again.

Please note that new content may take a few days to be indexed by the search engine and therefore to appear in the results.

Print Version
Share this article
See also
Project web site
Project information on CORDIS






  Top   Research Information Center