UMPIRE

Use of a Multidrug Pill In Reducing cardiovascular Events

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Contract/Grant agreement number
: 241849
EC contribution
: € 2,999,866.00
Duration
: 36 months
Starting date
: 01/02/2010
Keywords
: Polypill Red Heart Pill Cardiovascular disease Adherence Equitable access.
Project web-site
: http://www.spacecollaboration.org

The use of preventive medications in people at high risk of cardiovascular disease is conceptually straightforward and yet in practice the adoption is disappointingly low and there is wide international variation. There are several barriers that might explain this shortfall and variation. The simplicity and economy of a polypill strategy might overcome some of these barriers.

The “Use of a Multidrug Pill In Reducing cardiovascular Events” (UMPIRE) trial assesses whether a polypill strategy (combining aspirin, a statin and two blood pressure lowering agents) will improve adherence to guideline-indicated therapies and lower blood pressure and cholesterol in people with established cardiovascular disease.


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