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Diabetes and Obesity

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Diabetes

Diabetes or diabetes mellitus - a disease characterised by abnormal blood sugar levels - represents a growing threat to human health.
The most prevalent forms of diabetes are caused by decreased production of or sensitivity to insulin, a pancreatic hormone that allows the body to absorb sugar. With deficient insulin function, sugar accumulates in the blood, leading to vascular damage. Symptoms include dehydration, fatigue and nausea, while long-term complications include heart disease, kidney failure, retinal damage and blindness, nerve damage and risk of amputation.
Except for genetic conditions or special types of diabetes (like type-1 diabetes), it is often a preventable chronic disease through a healthy lifestyle starting in childhood. Although there is no cure, the disease is treatable and can be managed by insulin supplementation in case of diabetes type 1, or a combination of diet, physical activity, medication and insulin supplementation in case of diabetes type 2.

In the last decade, an explosion in diabetes incidence occurred, not only in the EU, but throughout the world. At present, diabetes affects around 250 million people worldwide, and the International Diabetes Federation estimates that by 2025 this figure will increase to over 380 million. In the EU-27 alone, the prevalence estimate is close to 9 % of the population aged between 20 and 79 years. This means that over 31 million people are now living with diabetes in the EU-27. Many people have diabetes for years and simply do not realise it until the symptoms appear.

In recognition of this growing problem the EU has been continuously supporting research on diabetes through framework programmes. In the Seventh Framework Programme (FP7; 2007-2013) the focus is on the causes of the different types of diabetes, and their prevention and treatment, with special attention to juvenile diseases and factors operating in childhood.

Obesity

Obesity is associated with many diseases, including cardiovascular diseases or diabetes mellitus type 2 and has therefore been shown to reduce life expectancy. While only recently identified as a major health concern, obesity levels have been growing steadily. According to the WHO, obesity has tripled over the past two decades: one in five Europeans is expected to be obese in 2010. The condition threatens to rank among the biggest causes of premature death in both the industrialised and emerging economies.

In 2006 the European member states of the WHO have signed the European Charter on Counteracting Obesity in order to curb the epidemic and reverse the trend.

In recognition of a need for action the EU supports research in this area under the Seventh Framework Programme (FP7; 2007-2013). The focus is on multidisciplinary approaches including genetics, life style and epidemiology, with special attention on juvenile diseases and factors operating in childhood. Advancing our understanding of the interaction between food, nutrition, genetics and health is a key to making our diets healthier and to combat obesity.

Up to December 2011 more than EUR 123 million has been made available under the FP7 to support 27 projects in the area of diabetes and obesity.

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