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Uniformity in Testing and Monitoring HIV Resistance
Framework programme:
Project number:
EC contribution:
€ 375,000
24 months
Starting date:
1 January 2005

Keywords: HIV drug resistance; virology; epidemiology; developing countries; WHO; SPREAD


Antiretroviral drugs are increasingly being provided to patients living with HIV in developing countries. Experience gained in Europe and North America has shown that the use of these drugs dramatically reduced mortality but is also associated with the emergence of drug resistant HIV. Surveillance of drug resistant HIV in developing countries is therefore important, as the spread of a resistant virus could seriously hamper the fight against the AIDS pandemic.
The EU Fifth Framework Programme (FP5)-funded Strategy To Control Spread of HIV Drug Resistance, (SPREAD) network has gained a leading role in the area of surveillance of HIV drug resistance. Within UNITE-MORE, SPREAD will closely co-operate with the World Health Organisation (WHO) to support the establishment of a uniform global network for HIV drug resistance surveillance.
The activities of UNITE-MORE can be divided into three main areas: (i) supporting the selection, and training of national HIV drug resistance surveillance teams in Eastern Europe, Africa, Asia and Latin-America, (ii) supporting the development of common clinical laboratory standards for the monitoring of HIV resistance (standard protocols, sample collection methods, and standard data storage and analysis), and (iii) supporting the training and operational activities of the country HIV drug resistance surveillance teams.
UNITE-MORE will actively contribute to the further development, transfer and take-up of the FP5-funded SPREAD clinical laboratory guidelines and systems at the global level. Further, UNITE-MORE will contribute to the objectives of the European Research Area (ERA) notably the opening up of ERA to third countries (specifically poor-resource countries), increased networking at the global level and raising the scientific and technological profile of Europe.

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