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MALVECASIA


Malaria

Monitoring Insecticide Resistance and Mapping Malaria Vectors in Southeast Asia : A Prerequisite for Sustainable Malaria Vector Control
Framework programme:
5
Project number:
ICA4-CT-2002-10041
EC contribution:
€ 1 433 000
Duration:
40 months
Type:
RS
Starting date:
1 September 2002

Summary:

New tools for improving sustainable control of malaria vectors in Southeast Asia will be developed. An adapted monitoring system to detect early development of insecticide resistance will be set up and molecular and biochemical tests will be developed to explore the resistance mechanisms involved. At the end of the project, the insecticide resistance status will be available for at least 120 sites, as will a decision tree for the management of operational implications. A geographical information system (GIS) on vector distribution (both primary and secondary vectors) and insecticide resistance will be developed. A model will developed to predict vector distribution and associations of species by environmental factors. This will be a practical tool to delineate malaria risk areas, to improve the targeting of vector control and assess the resistance status of vectors.

Objectives:

The objectives are:

1) to define the insecticide resistance status by (sibling) species in different physio-geographical regions of Southeast Asia
2) to study the operational implications of Malaria Control Programmes for the emergence and spread of insecticide resistance in malaria vectors
3) to explore the different mechanisms (insecticide metabolism, target-site resistance) involved in insecticide (cross) resistance
4) to determine the environmental determinants on vector distributions, associated disease risks and development of insecticide resistance in the region
5) to investigate the systematics/taxonomy of secondary vectors and establish their involvement in malaria transmission
6) to consolidate the research capacity of an existing network in Southeast Asia.

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