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Blocking Malaria Transmission by Vaccines, Drugs and Immune Mosquitoes: Efficacy Assessment and Targets
Framework programme:
Contract/Grant agreement number:
EC contribution:
2,900,000 €
48 months
Funding scheme:
Focused research project
Starting date:
Project Web site:

Keywords: malaria, Anopheles, Plasmodium, transmission blocking, refractory mosquitoes


Malaria is a serious global health problem. Half the world’s population is at high risk of contracting malaria and almost 500 million people are infected every year. Malaria transmission has been eradicated from Europe largely through vector control. However, the health burden greatly affects global economic growth. In addition, more people are travelling in endemic areas and thousands of malaria cases are imported into the EU every year. Although the problem is multifaceted, it is recognised that interventions targeted at the vector stages will be central in the fight against the disease.

Transmission of malaria through its mosquito vector is the weakest link in the chain that maintains the disease cycle: parasite numbers reach their lowest ebb during their early developmental stages in the mosquito. This bottleneck represents a likely point for intervention that could provide transmission blocking.

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