Keywords: tuberculosis, training, research
The relative lack of funded tuberculosis (TB) research over the last several decades has been acknowledged by the Stop TB Partnership and Global Stop TB Plan. In order to sustain research momentum over the next few decades, the next generation of TB researchers, particularly from developing countries, will have to be nurtured and supported. This project seeks, by building on existing research and capacity development programmes, to create a scientific fellowship programme focused on TB, and to facilitate career progression of developing country clinical scientists through a programme offering scientific training and a network of mentors.
If Africa is to play a meaningful role in contributing to global health research in the future, it will require accelerated development of skilled biomedical researchers of an international calibre. There is also an urgent need to invigorate ageing academic communities, in countries such as South Africa and India, with young scientists who are capable of developing their own internationally recognised research programmes.
TBsusgent will train a new group of TB research workers with the following strengths:
In addition, capacity building through scientific projects supporting PhD, MD and Masters students will focus on the following areas:
WP2: Immunology and molecular biology. This course will encompass cutting edge studies of regulatory immunological pathways in the human lung in subjects with TB.. Other studies will focus on the effect of tobacco smoke on TB-specific pulmonary host immune responses.
WP3: T cell assays (P2). This will focus on T cell assays for the diagnosis of LTBI and active TB (pulmonary and extra-pulmonary TB) using cells from different body compartments.
WP4: Diagnostics and markers of disease activity (P 3, 4 and 7). The diagnostics aspect will focus on field trials of newer and merging technologies for the diagnosis of TB.
WP5: Clinical trials programme. The clinical trials programme will focus on studies of XDR TB, impact of smoking cessation and vitamin D as interventions for infectious diseases.
WP6: Epidemiology and bio-statistics (P6). This course will focus on epidemiology and biostatistics.
WP7: Workshops, courses and seminars (all partners).
TBsusgent will build upon our current links and programme research (funded by the UK Department for International Development, the European Union, the European & Developing Countries Clinical Trials Partnership, the Foundation for Innovation in New Diagnostics and the Canadian Institutes of Health Research in multiple centres. In Africa these will be in Zimbabwe, Ethiopia, The Gambia, Madagascar, Senegal, South Africa, Tanzania and Zambia. In India they will be in Delhi and Tirupati, and in Europe they will be in Italy, London and Germany.
Dr Keertan Dheda
Centre for Infectious Diseases and International Health
University College London
|Nº||Participant organisation name||Country||Other Information|
|1||Prof. Leonardo Sechi||Dipartmento di Scienze Biomediche
|2||Prof. Surendra Sharma||All India Institute of Medical Sciences
|3||Prof. Mohan Alladi||Sri Venkateswara Institute of Medical Sciences
|4||Dr. Rodney Dawson||University of Cape Town
|5||Prof. Madhukar Pai||McGill University
|6||Prof. Michael Hoelscher||LMU University of Munich