Apart from malaria, the three most important diseases caused by protozoan infections are African Trypanosomiasis, Leishmaniasis/Kala-azar and Chagas disease. Taken together, these three diseases affect millions of people around the world, and are estimated to be responsible for more than 110.000 deaths every year.
| PRIORITY DISEASES |
Infectious Agent |
| KEY RESEARCH GAPS |
| Discovery and Development |
Disease Control and Implementation research |
|
| Human African Trypanosomiasis (sleeping sickness) |
Trypanosoma brucei |
| New drugs and drug targets, vaccines |
Easy and affordable diagnostics, Epidemiology and surveillance, vector control |
|
| Leishmaniasis(Kala Azar) |
Leishmania genus |
| New drugs and drug targets, effective vaccines |
Epidemiology, diagnostics (early-stage), vector control |
|
| Chagas |
Trypanosoma cruzi |
| New drugs and drug targets (in particular for chronic infections), vaccines |
Epidemiology, diagnostics, vector control |
|
