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Helminth diseases Projects

Sustainable Control of Onchocerciasis Today and Tomorrow

Project Number
: 032321
: 48 months
EC contribution
: € 2,800,000
: Specific Targeted Research Projects (STREPs) and Coordination Actions (CAs) for Developing countries (DEV)
: Helminth diseases
Starting date
: 01/11/2006


The purpose of this project is to improve sustainable control of onchocerciasis (river blindness) through refinement of existing chemotherapeutic regimes and identification of new targets and approaches for integrated control that will combine chemotherapy with vaccination.

The demand for these studies comes from:

  1. the need to control re-emergence of onchocerciasis in regions where transmission had been interrupted;
  2. indications consistent with the emergence of ivermectin resistance; and
  3. concern about adverse side reactions following ivermectin treatment in loiasis endemic areas.

There are three primary objectives:
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