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European Commission Colloquium
Helminth infections: Prevention and Treatment of Diseases and Co-infections Involving Helminths


25 September 2012, Paris, France
Muséum national d'Histoire naturelle

Programme

08.30 – 09.00 Registration

09.00 – 09.45: Session 1 – Setting the scene

Chair: Ole F. Olesen

09.00 – 09.05 Opening Remarks
M. Thomas Grenon, Director Museum National d’Histoire naturelle, France

09.05 – 09.15 EU research on helminths
Ole F. Olesen ( 439KB), European Commission, Belgium

09.15 – 09.30 EDCTP embraces neglected infectious diseases
Pauline Beattie ( 436KB), European and Developing Countries Clinical Trials Partnership, the Netherlands

09.30 – 09.45 The 50 Cent Solution That Can Change a Billion Lives
Neeraj Mistry ( 876KB), Global Network for Neglected Tropical Diseases, US

09.45 – 11.15: Session 2 – Dissecting the immunological interplay between poverty related diseases and helminth Infections

Chairs:
Giuseppe Pantaleo, Centre Hospitalier Universitaire Vaudois, Switzerland
Alison Elliott, Uganda Virus Research Institute, Uganda

09.45 – 10.00 Overview of the IDEA Project
Giuseppe Pantaleo ( 1.88MB), Centre Hospitalier Universitaire Vaudois, Switzerland

10.00 – 10.20 HIV/TB co-infection: clinical and diagnostic implications
Alimuddin Zumla, University College London, UK

10.20 – 10.40 HIV/helminth co-infection: modulation of immune response
Pietro Pala, Uganda Virus Research Institute, Uganda

10.40 – 10.55 Impact of helminth infections on vaccination
Ayola Akim Adegnika ( 1.36MB), Hospital Albert Schweitzer de Lambaréné, Gabon

10.55 – 11.15 Interferons: the good, the bad and the ugly
Rafick Sekaly, Vaccine & Gene Therapy Institute, US

11.15 – 11.30 Coffee Break

11.30 – 13.30: Session 3 - Development of novel vaccines for control of helminth infections

Chairs:
Cornelis Hokke, Leiden University Medical Center, the Netherlands
Maria Yazdanbakhsh, Leiden University Medical Center, the Netherlands

11.30 – 11.40 Overview of TheSchistoVac
Cornelis Hokke, Leiden University Medical Center, the Netherlands

11.40 – 11.50 Overview of E-PIAF
David W. Taylor, University of Edinburgh, UK

11.50 – 12.10 Nematode vaccines and immunology – state of the art
Rick Maizels ( 4.59MB), University of Edinburgh, UK

12.10 – 12.30 Schistosomiasis vaccine development: pointers from animal models of protective immunity
Alan Wilson ( 525KB), University of York, UK

12.30 – 12.50 The impact of epidemiology on the design and feasibility of control and elimination of helminth infections
Maria-Gloria Basanez ( 2.09MB), Imperial College London, UK

12.50 – 13.10 Nematode vaccine target discovery
Ben Makepeace ( 4.24MB), University of Liverpool, UK

13.20 – 13.30 Identification of novel schistosome vaccine targets by transcriptomics
Karl Hoffmann ( 27.3MB), Aberystwyth University, UK

13.30 – 15.00 Lunch

15.00 – 16.45: Session 4 - Drug development for helminths

Chair:
Raymond Pierce, Centre d'Infection et d'Immunité de Lille, Institut Pasteur de Lille, France

15.00 – 15.05 Session Introduction
Raymond Pierce, Centre d'Infection et d'Immunité de Lille, Institut Pasteur de Lille, France

15.05 – 15.35 Helminth infections - the challenges of drug R&D
Marcel Tanner ( 2.54MB), Swiss Tropical and Public Health Institute, Switzerland

15.35 – 15.50 Doxycycline for treatment of onchocerciasis
Achim Hoerauf ( 1.79MB), Institute of Medical Microbiology, Immunology and Parasitology, Germany

15.50 – 16.10 Epigenetic drug discovery
Manfred Jung ( 2.55MB), Albert Ludwigs University Freiburg, Germany

16.10 – 16.25 Schistosome histone modifying enzymes as drug targets: the SEtTReND project
Raymond Pierce ( 573KB), Institut Pasteur de Lille, France

16.25 – 16.45 SmHDAC8: from structural analysis to specific inhibitors
Christophe Romier, Institut de Génétique et de Biologie Moléculaire et Cellulaire, France

16.45 – 17.00 Coffee Break

17.00 – 18.00: Round table discussion

Chairs:
David W. Taylor, University of Edinburgh, UK
Ole F. Olesen, European Commission, Belgium