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Bacteria Diseases

The neglected bacterial diseases comprise serious and often lethal conditions caused by a large number of bacteria, ranging from the mycobacteria family (causing leprosy and Buruli ulcer) to Chlamydia (causing trachoma) and gastrointestinal bacteria such as enterotoxigenic E. coli (ETEC) and Shigella (both causing infantile diarrhoea).


PRIORITY DISEASES Main Infectious Agent
KEY RESEARCH GAPS
Discovery and Development Disease Control and Implementation Research
Buruli ulcer Mycobacterium ulcerans
Basic immunology for future vaccine development, drug and diagnostic development Epidemiology, diagnostics
Leprosy Mycobacterium leprae
Basic immunology for future vaccine development, drug and diagnostic development Diagnostics
Trachoma Chlamydia trachomatis
Vaccine development, immunopathogenesis, predictive animal models Diagnostics
Infantile diarrhoea Enterotoxigenic Escherichia coli (ETEC)

Shigella genus
Vaccines, drug resistance Diagnostics (able to differentiate between gut infections), Improved control