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RaSP


Preparedness and capacity building for emerging epidemics

Rapid SPR for parallel detection of pathogens in blood

EC contribution
: € 1 556 702
Duration
: 36 months
Starting date
: 01/01/2007
Instrument
: STREP
Keywords
: HIV, hepatitis C, hepatitis B, syphilis, blood screening, surface plasmon resonance
Project Number
: SP5A-CT-2006-044515
Web-site
: http://www.rapid-spr.com

Summary:

In the RaSP project, the partners will develop a fast, cheap and at the same time very sensitive method, which has the potential to detect more than 100 blood pathogens simultaneously. A new type of surface plasmon resonance (SPR) transducing principle will be exploited, which allows an essential increasing of the sensitivity compared to the state-of-the-art SPR systems. The consortium aims at the simultaneous detection of the pathogens HIV, hepatitis C, hepatitis B and syphilis to demonstrate the capabilities of the system. In parallel, a simple version of the system will be set up that will allow for the detection of the presence of any of the mentioned blood pathogens.

Problem:

Biological materials like blood, tissues and organs now represent a daily routine material that our hospitals and research institutes handle for many preventive, therapeutic, and research applications. They represent hope for many medical situations, but at the same time they pose a risk of transmitting diseases via blood transfusion, tissue transplantation or organ transplantation. Thus, there is an urgent need to improve the technologies used for screening diseases such as HIV and hepatitis C. The same need exists to test donor blood in a cheap and fast way, especially in less developed countries where the rate of infected blood is high due to high prevalence of diseases.

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