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Uniformity in testing and monitoring HIV resistance
EC contribution
: € 375.000
: 24 months
Starting date
: 01/01/2005
Funding scheme
: Specific Support Action
: HIV drug resistance, virology, epidemiology, developing countries, WHO, SPREAD
Contract/Grant agreement number
: LSHP-CT-2004-516030
Project web-site
: Not available


Antiretroviral drugs are increasingly being provided to patients living with the human immunodeficiency virus (HIV) in developing countries. Experience gained in Europe and North America has shown that the use of these drugs dramatically reduced mortality but is also associated with the emergence of drug-resistant HIV. Surveillance of drug resistant HIV in developing countries is therefore important, as the spread of a resistant virus could seriously hamper the fight against the AIDS pandemic.

The EU Fifth Framework Programme (FP5)-funded Strategy To Control Spread of HIV Drug Resistance, (SPREAD) network has gained a leading role in the area of surveillance of HIV drug resistance. Within UNITE-MORE, SPREAD will closely co-operate with the World Health Organization (WHO) to support the establishment of a uniform global network for HIV drug resistance surveillance.

The activities of UNITE-MORE can be divided into three main areas: (i) supporting the selection, and training of national HIV drug resistance surveillance teams in Eastern Europe, Africa, Asia and Latin-America, (ii) supporting the development of common clinical laboratory standards for the monitoring of HIV resistance (standard protocols, sample collection methods, and standard data storage and analysis), and (iii) supporting the training and operational activities of the country HIV drug resistance surveillance teams.

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