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Improved methods for the diagnosis of ruminant alphaherpesvirus infections in relation to the control of infectious bovine rhinotracheitis (ibr)

Last updating 1999

Contract nr: FAIR-CT95-0316
Project nr: 316
Project type: SC
Starting date: 01/03/1996
Duration: 36 months
Total cost: 1,643,900 EUR
EC Contribution: 896,500 EUR
Scientific Officer: Isabel MINGUEZ-TUDELA
Research topic: Animal health

Bovine herpesvirus 1 (BHV-1) infection in cattle is a disease of major economic concern in Europe, both in countries where this infection has been eradicated and in those where the control of infectious bovine rhinotracheitis (IBR) is currently or will be undertaken. Successful control of IBR depends on the use of efficient, sensitive and specific diagnostic tests. The efficiency of the existing diagnostic methods is compromised by the existence of serological cross-reactivity between BHV-1 and the other closely related alphaherpesviruses.

The aim of this research is:

  • to assess the risk of cross-infection between BHV-1 and other alphaherpesviruses in ruminants;
  • to develop diagnostic methods capable of differentiating the different ruminant alphaherpesviruses infections.

The work will be subdivided into 3 phases : in vivo evaluation of cross-infections of cattle; serological differentiation of ruminant alphaaherpesviruses related to BHV-1 and genomic differentiation of ruminant alphaviruses related to BHV-1.

Etienne THIRY
Université de Liège
Boulevard de Colonster 20
Bat. 34 Bis

B-4000 Liège
Tel.: +32 4 366 42 50
Fax: +32 4 366 42 61


  • Malcolm BANKS
    Central Veterinary Laboratory
    Woodham Lane
    UK-KT15 3NB New Haw - Addlestone
    Tel.: +44 1932 35 75 09
    Fax: +44 1932 35 72 39

  • Monika ENGELS
    University of Zurich
    Winterthurerstrasse, 266 A
    CH-8057 Zürich
    Tel.: +41 1 365 15 36
    Fax: +41 1 363 01 40

  • Hugh W. REID
    Moredun Foundation for Animal Health and Welfare
    Gilmerton Road, 408
    UK-EH17 7JH Edinburgh
    Tel.: +44 131 664 32 62
    Fax: +44 131 664 80 01

  • Sandor BELAK
    The National Veterinary Institute
    P.O. BOX 585
    S-751 23 Uppsala
    Tel.: +46 18 67 40 00
    Fax: +46 18 17 45 17

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