On the European market, there is a lack of innovative biomaterials that aid in the regeneration of wound tissue. This project aims to design and develop optimal textile forms for medical applications made from dibutyrylchitin (DBC) and chitin, a fishery byproduct. A method for the synthesis of dibutyrylchitin has recently been developed. DBC is easily soluble in common recyclable solvents and has film/fibre forming properties, and chitin can be regenerated (RC). The products are assumed to have wound healing properties. This opens the way for the development of novel functional biomaterials made from DBC and RC, including the production of fibres, yarns and non-woven materials. The textiles will be designed to requirements and will be characterised on mechanical, physico-chemical and biochemical-medical (in vitro, in vivo) properties. Initiations for the approval of the medical products will be made.
Joint efforts will be made between the chemical and textile companies and the universities to develop the production of DBC, the spinning technology of DBC and low dose DBC/cellulose fibres and yarns, the production of DBC textiles, and the regeneration of chitin in manufactured DBC products. An industrial company, active in the medical field, will co-operate with the laboratories/hospital where the bioactivity and biocompatibility of these novel biomaterials can be assessed. The project will generate novel biomaterials and medical items that accelerate the wound healing with no scar formation and undesirable effects, that are easy to handle and could be prepared as self-adhering dressings. The project will improve the competitiveness of European industry through the sustainable production and rational utilisation of natural resources with the special emphasis on new technologies.
Progress to Date
1) The production of chitin from a different origin.
2) Preliminary characterisation.
3) The development of technology to produce dibutyrylchitin (DBC).
Chitin from a different origin has been analysed.
FISHERIES AND AQUACULTURE, HUMAN HEALTH AND WELLBEING
Scientist responsible for the project
||01 January 2003
||1 831 368 €
|Total EC contribution
||1 284 696 €