Table 13-6: Known prehaptens and prohaptens.
Fragrance substance |
Activation by air oxidation |
Bioactivation (oxidation) |
Bioactivation (hydrolysis) |
Cinnamyl alcohol |
|
x |
|
Eugenol |
|
x |
|
Eugenyl acetate |
|
x |
x |
Geranial |
x |
x |
|
Geraniol |
x |
x |
|
Geranyl acetate |
x |
x |
x |
Isoeugenol |
|
x |
|
Isoeugenyl acetate |
|
x |
x |
Limonene |
x |
|
|
Linalool |
x |
|
|
Linalyl acetate |
x |
|
|
alpha-Terpinene. |
x |
x |
|
Source:
SCCS, Opinion on Fragrance allergens in cosmetic products, page 118