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This section on health in the EU has been created as a trustworthy gateway to a wide range of information and data on health-related issues and activities at both European, national and international level. The content is produced by the European Commission, the Member States of the EU and the European Economic Area (EEA), plus EU candidate countries; by international organisations; and by pan-European non-governmental organisations in the area of public health.

Gardedam Therapeutics announces a crowdfunding campaign: Novel Parkinson's and Alzheimer's therapies    epda.eu.com

Gadedam Therapeutics (Gardedam) launched a crowdfunding campaign with the objective of raising $195,000 USD to support and advance its novel Parkinson's and Alzheimer's disease drug disovery efforts.[...]

Gait and balance in Parkinson's disease subtypes: objective measures and classification considerations    epda.eu.com

Clinical assessments of the disturbances seen in patients with the PIGD subtype are not consistent with objective measures; overlapping between the groups is seen in many objective features of gait a[...]

CHMP Recommends Approval of Xadago™ (Safinamide) to Treat Parkinson´s Disease in the EU    epda.eu.com

First New Chemical Entity (NCE) in 10 years to receive a positive opinion from CHMP for the treatment of Parkinson's disease (PD) patients[...]

Helicobacter Pylori infection is associated with worse severity of parkinson's disease    epda.eu.com

This is the largest cross-sectional study to demonstrate an association between HP positivity and worse PD motor severity.[...]

Mysimba recommended for approval in weight management in adults    europa.eu

Medicine to be used in addition to reduced-calorie diet and physical activity[...]

Events - Novel Approaches to the Treatment of Cancer - 4-5 February 2015, London, UK    europa.eu

This event will cover: new paradigms for targeted therapies, new anti-cancer agents ~ industry viewpoint, novel approaches to the treatment of breast cancer, melanoma and pancreatic cancer, drug deve[...]

Support the European Data in Health Research Alliance!    epha.org

A new European Data in Health Research Alliance was launched in early December. This campaign, supported by a number of health organisations active across Europe and representing research, patient an[...]

EFA – Air travel for patients requiring oxygen should be facilitated not hindered    env-health.org

On World Chronic Obstructive Pulmonary Disease (COPD) Day, the European Federation of Allergy & Airways Diseases Patients´ Association (EFA) called on European air travel authorities to rule on t[...]

Air Pollution: Are EU Policy Makers Aware of the Danger for Public Health?    epha.org

While experts highlight the health effects and economic costs of air pollution, the European Commission is planning to amend the air quality proposal which is likely to have significant benefits for [...]

Cost of deep brain stimulation for the treatment of Parkinson's disease by surgical stimulation sites    epda.eu.com

Provider costs were similar for the 144 GPi and 130 STN patients (GPi: $138,044 vs. STN: $131,822; difference = $6,222, 95% confidence interval [CI]: $42,125 to $45,343). Societal costs were also sim[...]

EPDA Move for Change survey shows Parkinson's care standards are lagging just one in 10 patients are diagnosed by a disease ex    epda.eu.com

Care provision in Parkinson's disease is falling dismally short of the standards patients and carers have every right to expect, research across Europe indicates.[...]

Characterizing motor and non-motor aspects of early-morning off periods in Parkinson's: An international multicenter study    epda.eu.com

Results: The results demonstrate that EMO periods are common and occur in 59.7% of subjects across all disease stages in line with other reports. However, importantly, in 88.0% of those, EMOs were fo[...]

Back to the basics: regular exercise matters in Parkinson's: Results from the National Parkinson Foundation registry study    epda.eu.com

Regular exercisers at baseline was associated with better QOL, mobility, and physical function, less progression of disease, less caregiver burden and less cognitive decline one year later, after con[...]

Concomitant development of hypersexuality and delusional jealousy in patients with Parkinson's disease: A case series    epda.eu.com

Discussion: Hypersexuality and delusional jealousy may occur independently in PD patients on dopamine agonist therapy, but may develop together probably reflecting a common alteration of sexuality (s[...]

Hippocampal volume and white matter disease in the prediction of dementia in Parkinson's disease    epda.eu.com

Conclusions: Hippocampal volume is a major factor predicting the development of mild cognitive impairment and dementia in PD. White matter hyperintensity also contributes to the longitudinal cognitiv[...]

Comparison of sleep and other non-motor symptoms between SWEDDs patients and de novo Parkinson´s disease patients    epda.eu.com

Conclusions: The patients with SWEDDs have less non-motor problems than newly diagnosed untreated PD patients. Given the difficulty distinguishing between SWEDDs and early PD, identifying some of non[...]

Risk of Parkinson's disease following severe constipation: A nationwide population-based cohort study    epda.eu.com

The association between constipation at the beginning of the study and the incidence of PD was examined using a Cox regression model. Information regarding comorbidities and concomitant medications u[...]

Parkinson's Disease Severity and Use of Dopaminergic Medications    epda.eu.com

The outcomes measured at the beginning of the study showed lower disease burden for participants on initial DA monotherapy compared to those taking combined LD and DA therapy after controlling for ag[...]

Innovation in atrial fibrillation therapy    escardio.org

Left atrium assessment and left atrium fibrosis among the areas where innovations in atrial fibrillation are revolutionizing practice. Topics: Echocardiography (Non-invasive imaging), Non-invasive im[...]

Acute chest pain: game changer or waste of resources?    escardio.org

Echocardiography, cardiac CT scan and cardiac MRI all offer promise for the assessment of patients with chest pain, but improved strategies for clinical risk assessment are needed to optimize selecti[...]

Interventricular Interactions in Congenital Heart Disease    escardio.org

Multimodality assessment of size, shape, deformation and function is key to understanding Interventricular interactions in Congenital Heart Disease. The joint session between the EACVI and ASE explor[...]

NEW! ESC Council on Hypertension    escardio.org

Created in September 2014 the ESC Council on Hypertension announces a new era for hypertension in the ESC. As Chairperson, Professor Antonio Coca will lead this new Council to increase its contributi[...]

The Heart in 3D: new frontiers    escardio.org

TEE before, during and after surgery is necessary to check indications, verify operative success and monitor long-term follow-up. Topics: Echocardiography (Non-invasive imaging), Non-invasive imaging[...]

Controversies in monitoring disease    escardio.org

Transthoracic echo remains first-line imaging for monitoring of bicuspid aortic valve and screening for ischemia in patients undergoing radiotherapy, but CTA and MRA also have role to play. Topics: E[...]

Heart disease patients advised to avoid being outside in rush hour traffic    escardio.org

Experts recommend reducing air pollution exposure and decreasing use of fossil fuels: Obese people and those with diabetes may be at higher risk of the cardiovascular effects of pollution, while air [...]

Heart failure with preserved ejection fraction – state of the art    escardio.org

Discussion of diagnosis, assessment and treatment of heart failure with preserved ejection fraction underlines the need for further clinical research in this area. Topics: Echocardiography (Non-invas[...]

Yoga has the same potential as exercise to reduce the risk factors of cardiovascular disease    escardio.org

Following a systematic review of 37 randomised controlled trials, investigators from the Netherlands and USA have found that yoga may provide the same benefits in risk factor reduction as such tradit[...]

Experimental Ebola treatments still at early stage of development    europa.eu

For robust scientific assessment more information on safety and efficacy needed[...]

Ebola: Exit screening report presented to the Health Security Committee    europa.eu

Ebola: Review of exit screening procedures at international airports in affected countries - Directorate General for Health & Consumers[...]

Scientific guideline: Guideline on the use of minimal residue disease as an endpoint in chronic lymphocytic leukaemia studies, draft: consultation open    europa.eu

The scope of this document is to describe the basis and regulatory requirements for the use of minimal residue disease (MRD) as an intermediate endpoint to predict clinical benefit in trials in chron[...]

Cleaner air would offer major health benefits in the Balkans    env-health.org

Three briefings released today by HEAL highlight the heavy toll on health resulting exposure to poor air quality in Bulgaria, Serbia, and Montenegro. INFORMATION RELEASE Brussels, 15 December 2014 - [...]

Senior Visiting Scientist Award 2014    iarc.fr

The recipients of the 2014 highly competitive Senior Visiting Scientist Award, currently at IARC, are: Professor Michael Leitzmann from the University of Regensburg, Regensburg, Germany, Professor Wa[...]

Cancer Country Profiles 2014 now available!    uicc.org

Global Education and Training Initiative Global Access to Pain Relief Initiative Global Initiative for Cancer Registry Development Cancer Country Profiles 2014 now available! The Cancer Country Prof[...]

Spotlight on the Cancer Prevention Network: Multimedia Library    uicc.org

Global Education and Training Initiative Global Access to Pain Relief Initiative Global Initiative for Cancer Registry Development Spotlight on the Cancer Prevention Network: Multimedia Library Join[...]

Distinguishing Idiopathic Parkinson's From Other Parkinsonian Syndromes By Breath Test    epda.eu.com

Conclusions: Exhaled breath analysis with nanoarray is a promising approach for a non-invasive, inexpensive, and portable technique for differentiation between different Parkinsonian states. A larger[...]

Anxiety in Parkinson's disease: symptom dimensions and overlap with depression and autonomic failure    epda.eu.com

Conclusion: Anxiety in PD comprises affective and somatic symptom dimensions. The affective subscale of the BAI is not influenced by motor or autonomic symptoms, and may therefore prove useful for fu[...]

ACADIA Pharmaceuticals Presents Caregiver Burden Data at the International Congress of Non-Motor Dysfunctions in Parkinson's Dis    epda.eu.com

Data from an analysis of Phase III studies in patients with PDP showed that treatment with NUPLAZID reduced caregiver burden compared to PDP patients on placebo.[...]

Longitudinal midbrain changes in early parkinson's disease: Iron content estimated from R2*/MRI    epda.eu.com

Conclusions: High field MRI demonstrates lateral SNc abnormalities that progress over 3 years in early PD consistent with increased iron content in those with more advanced disease, corresponding to [...]

Research Headlines - Saving time, saving lives: monitoring cancer treatments    europa.eu

Is a cancer treatment working? Often doctors won t know for months. By developing a new technique that quickly reveals a tumour through its metabolic consumption of glucose, an EU-funded project has [...]

Daily wrap up - 2014 World Cancer Congress    uicc.org

Australia was at the centre of the global fight against cancer this month, with over 2,700 cancer advocates from 115 countries descending on Melbourne for the 2014 World Cancer Congress. Under the b[...]

Mitochondrial dysfunction in Parkinson's disease: a possible target for neuroprotection    epda.eu.com

This review will discuss the evidence supporting mitochondrial dysfunction in Parkinson's disease pathology as well as treatment strategies that target the mitochondria.[...]

Taste function in early stage treated and untreated Parkinson's disease    epda.eu.com

Study findings suggest that suprathreshold measures of taste function are influenced by PD and that this disease differentially influences taste function on anterior (CN VII) and posterior (CN IX) to[...]

Stem cells from adult nose tissue used to cure Parkinson's disease in rats    epda.eu.com

Scientists have for the first time used adult human stem cells to cure rats with Parkinson's disease, a neurodegenerative illness that currently has no cure.[...]

Controversial fetal cell transplants revived for Parkinson's trials    epda.eu.com

For the last 25 years, using fetal tissue for scientific research has largely fallen out of favor in both the European and U.S. scientific communities. One of the most publicised uses of the controve[...]

Brains in the balance: New $11.5M grant fuels University of Michigan Parkinson's disease research center to aid patients    epda.eu.com

NIH grant creates Udall Center of Excellence for Parkinson's Disease Research focused on developing a treatment to prevent falls.[...]

Launch of Knowledge Summaries of Comprehensive Breast Cancer Control    uicc.org

Global Education and Training Initiative Global Access to Pain Relief Initiative Global Initiative for Cancer Registry Development Launch of Knowledge Summaries of Comprehensive Breast Cancer Contro[...]

Pramipexole Extended-Release: A Review of Its Use in Patients with Parkinson's Disease    epda.eu.com

Head-to-head trials are needed in order to fully define the role of pramipexole ER relative to other once-daily formulations of DAs (oral ropinirole and transdermal rotigotine). Nonetheless, by reduc[...]

Reduction of gastrointestinal symptoms in Parkinson's disease after a switch from oral therapy to rotigotine transdermal patch:    epda.eu.com

This study suggests that a switch from oral anti-PD medications to rotigotine transdermal patch may improve existing GI symptoms among patients with PD. Additional controlled studies are needed to co[...]

NGOs offer easy way for citizens to tell EU to stop exposures to hormone disrupting chemicals    env-health.org

The EDC-Free Europe coalition has launched an online platform to enable individuals to respond easily to an EU public consultation and tell the European Commission to remove hormone-disrupting chemic[...]

Gardedam Therapeutics announces a crowdfunding campaign: Novel Parkinson's and Alzheimer's therapies    epda.eu.com

Gadedam Therapeutics (Gardedam) launched a crowdfunding campaign with the objective of raising $195,000 USD to support and advance its novel Parkinson's and Alzheimer's disease drug disovery efforts.[...]

Released: TNM e-learning modules    uicc.org

Global Education and Training Initiative Global Access to Pain Relief Initiative Global Initiative for Cancer Registry Development On the occasion of the 2014 World Cancer Congress (WCC), eCancer an[...]

2014 World Cancer Leaders' Summit    uicc.org

Global Education and Training Initiative Global Access to Pain Relief Initiative Global Initiative for Cancer Registry Development The Economic Case for Cancer Control The 2014 World Cancer Congress[...]

Exploring nano-scale scaffolds for mending damaged hearts    europa.eu

EU-funded researchers have used advanced nanomaterials to engineer heart tissue, and have explored the development of innovative stem cell-based therapies that could greatly improve the recovery rate[...]

Capacity Building Project update    efanet.org

Meeting with RESPIRA, Portuguese EFA Member On November 15, EFA representatives travelled to Lisbon to meet with 14 members of EFA's member organisation RESPIRA, including recently appointed EFA Boar[...]

Implications of EMA’s Pharmacovigilance Risk Assessment Committee statement on ivabradine inclusion within ESC guidelines and ivabradine prescribing recommendations    escardio.org

As a result of new data from the SIGNIFY study (1), presented at ESC Congress 2014 and published simultaneously in the New England Journal of Medicine, the EMA's Pharmacovigilance Risk Assessment Com[...]

Factor analysis of The Hamilton Depression Rating Scale in Parkinson's disease    epda.eu.com

Conclusion: This analysis demonstrates that the factorial validity of the HAMD in PD is unsatisfactory. This implies that the scale is not appropriate for studying specific symptom domains of depress[...]

GBA-associated Parkinson's disease: Reduced survival and more rapid progression in a prospective longitudinal study    epda.eu.com

Conclusions: The mutational GBA status, rather than older age and age at onset, presents an important predictor for disease progression in this specific subgroup of PD patients.[...]

The Netherlands should do more to help workers with mental ill-health, says OECD    oecd.org

The Netherlands should increase support for workers suffering from mental health issues and their employers and tackle the continued social stigma and limited knowledge around such illnesses, accordi[...]

Parkinson's UK and Global Kinetics Corporation collaborate to provide promising new mHealth technology throughout UK    epda.eu.com

An innovative medical device designed in Australia to improve management of Parkinson's is to be made available in services in the United Kingdom, as part of a 12-month pilot project.[...]

High cancer burden due to overweight and obesity in most European countries    who.int

A new study by the International Agency for Research on Cancer (IARC), WHO's specialized cancer agency, shows that overweight and obesity are a major risk factor for cancer: responsible for an estima[...]

[Press release ahead of EPSCO Council meeting] How to put health at the heart of the Europe2020 Strategy    epha.org

Brussels, 28 November - Ahead of the Employment, Social Policy, Health and Consumer Affairs (EPSCO) Council on 1 December, EPHA has sent an open letter (1) to health ministers urging them to ensure t[...]

WHO project to combat noncommunicable diseases with major grant from Russian Federation    who.int

The WHO Regional Office for Europe will expand capacity in dealing with prevention and control of noncommunicable diseases (NCDs) such as cancer, cardiovascular disease, diabetes and chronic respirat[...]

CSF biomarkers and clinical progression of Parkinson disease    epda.eu.com

Authors found evidence of a link between higher levels of αSyn at baseline and worsening of motor symptoms and cognitive speed over 2 years in PD. Increased αSyn might be a marker of more intense syn[...]

‘Utter neglect’ of rheumatic heart disease revealed by results from global study    escardio.org

REMEDY study seeks to put an end to rheumatic heart disease in our own lifetime through the application of preventive measures: For progress to be made in preventing and treating this serious conditi[...]

Parkinson's nurses: a light in the darkness    epda.eu.com

This article article explores the work of Parkinson's nurses, their benefits and how Parkinson's UK supports them to care for those affected by the condition.[...]

Supporting people with Parkinson's in later life    epda.eu.com

All older people with Parkinson's will benefit from access to a specialist, comprehensive old-age assessment and nursing care that understands how symptoms can affect health and wellbeing, and is res[...]

Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats    epda.eu.com

In conclusion, authors here provide the first experimental evidence that different α-synuclein forms can propagate from the gut to the brain, and that microtubule-associated transport is involved in [...]

Apathy in untreated, de novo patients with Parkinson's disease: validation study of Apathy Evaluation Scale    epda.eu.com

The AES-S is a reliable and valid questionnaire for detecting apathy in PD. For screening purposes a 33/34 cut-off score is indicated, but a 38/39 cut-off score is necessary when a high specificity i[...]

ESC Webinar recording based on ESC Guidelines on Diabetes    escardio.org

Nicolas Danchin and Ramzi Ajjan explored the ESC Guidelines on Diabetes and answered this question: How to manage cardiovascular disease in the pre-diabetic and diabetic patients? the recording for F[...]

European Medicines Agency recommends measures to reduce risk of heart problems with Corlentor/Procoralan (ivabradine)    europa.eu

The European Medicines Agency (EMA) has completed a review of Corlentor/Procoralan (ivabradine) and has made recommendations aimed at reducing the risk of heart problems, including heart attack and b[...]

No consistent evidence of an increased risk of heart problems with testosterone medicines    europa.eu

The Coordination Group for Mutual Recognition and Decentralised Procedures - Human (CMDh), a regulatory body representing EU Member States, has agreed by consensus that there is no consistent evidenc[...]

Success Stories - A vision of personalising medicine for epilepsy patients    europa.eu

EpiPGX is a FP7-funded project that brings together clinical researchers, geneticists and computational biologists from leading centres across Europe to link genomics and treatment outcomes for patie[...]

Neuropsychological performance in LRRK2 G2019S carriers with Parkinson's disease    epda.eu.com

Conclusion: In AJ-PD, G2019S mutation status is associated with better attention (Stroop Word Reading), executive function (Stroop Interference) and language (Category Fluency) after adjustment for P[...]

Physical activity and risk of Parkinson's disease in the Swedish National March Cohort    epda.eu.com

Study results indicate that a medium level of physical activity lowers Parkinson's disease risk.[...]

Great Lakes Neurotech enters medical device app market with Kinesia One for monitoring Parkinson's disease    epda.eu.com

Great Lakes NeuroTechnologies announced today they have successfully transitioned their Kinesia technology for objective monitoring of Parkinson's disease to an app platform.[...]

ACCESSIBLE TOURISM IN THE HEART OF THIS YEAR'S EUROPEAN DAY OF PEOPLE WITH DISABILITIES    edf-feph.org

This website is supported by the European Union Programme for Employment and Social Solidarity – PROGRESS (2007-2013) source of growth for the economy in Europe, representing today 1.8 million busin[...]

Applause sign in advanced Parkinson's disease    epda.eu.com

Conclusions: The applause sign is present in late stage PD and correlates with a higher degree of cognitive impairment as established with accepted clinimetric tests. A higher degree of frontal lobe [...]

Diagnostic accuracy of Parkinson's disease and atypical parkinsonism in nursing homes    epda.eu.com

In a large population of Dutch nursing home residents, 20% of diagnoses within the parkinsonian spectrum were inaccurate. Almost 9% of residents had inadvertently received a diagnosis of parkinsonism[...]

Glucocerebrosidase mutations in primary parkinsonism    epda.eu.com

Conclusion: GBA dysfunction is relevant for synucleinopathies, such as PD and DLB, except for MSA, in which pathology involves oligodendrocytes, and the tauopathies PSP and CBD. The risk of developin[...]

Lifetime exposure to Estrogens and Parkinson's disease in California teachers    epda.eu.com

Conclusions: These results provide some support for the hypothesis that lifelong high estrogen is protective in PD, suggesting that the level and persistence of exposure over the long term may be imp[...]

Montreal Cognitive Assessment for the screening and prediction of cognitive decline in early Parkinson's disease    epda.eu.com

Conclusions: MoCA is a reliable tool in predicting cognitive decline in early PD. A MoCA score of 26 significantly increases the risk for progressive cognitive decline.[...]

Relationships among cognitive impairment, sleep, and fatigue in Parkinson's disease using the MDS-UPDRS    epda.eu.com

Results: Of these three frequent, and often inter-twined, non-motor complications, greater daytime sleepiness and fatigue were associated with worse cognitive impairment across the full spectrum of P[...]

Success Stories - Expanding insight into Alzheimer's disease    europa.eu

Chronic neurodegenerative diseases, such as Alzheimer's, Parkinson's and Huntington's, are all characterised by an inflammatory reaction within the brain. Until now, some of the factors behind this r[...]

Nordic countries estimate high costs from chemical exposure    env-health.org

Brussels, 17 November 2014 - A body representing Denmark, Finland, Iceland, Norway and Sweden has suggested that up to 40% of the health costs associated with several serious male reproductive probl[...]

Great Lakes Neurotech enters medical device app market with Kinesia One for monitoring Parkinson's disease    epda.eu.com

Great Lakes NeuroTechnologies announced today they have successfully transitioned their Kinesia technology for objective monitoring of Parkinson's disease to an app platform.[...]

DNAJC13 genetic variants in parkinsonism    epda.eu.com

Conclusion: Although the contribution of rare genetic variation in DNAJC13 to parkinsonisms remains to be further elucidated, this study suggests that, in addition to p.N855S, other rare variants mig[...]

Increased risk of Parkinson's disease in cataract patients: A population-based cohort study    epda.eu.com

Conclusions: Overall, this study discloses a 26% increased hazard of Parkinson's disease in cataract patients. Further studies are required to investigate whether cataracts are one of non-motor manif[...]

Type 2 diabetes reversible with lifestyle changes    escardio.org

Today is World Diabetes Day and this year's theme is Healthy Living and Diabetes. [...]

Research Headlines - New test for sexually transmitted virus could reduce cancer risks    europa.eu

One of the keys for treating and reducing the spread of sexually transmitted diseases is accurate, fast and affordable means of detection. This is especially true for the human papillomavirus (HPV), [...]

Survey reveals knowledge gaps among Parkinson's patients and caregivers    epda.eu.com

A recent survey of more than 1,500 Parkinson's disease (PD) patients, caregivers and physicians reveals that information and specialized care can help patients become more engaged in their own treatm[...]

Canadian Study of Neurological Conditions Provides New Vital Information on the Impact of Parkinson's Disease    epda.eu.com

Parkinson Society Canada is excited to share today's release of the report on The National Population Health Study of Neurological Conditions by the Public Health Agency of Canada in partnership with[...]

Conference on hormone associated cancers and EDCs in French Senate    env-health.org

In order to understand the increase of breast cancer cases in France, environmental factors especially EDCs exposure need to be taken in to account. This was the central theme of a recent conference [...]

Research Headlines - New stent to help lung cancer victims breathe easier    europa.eu

Many lung cancer patients have trouble breathing - and if they can't be cured, the struggle for air can become a relentless ordeal. Pulmonary stents - tubes inserted in the lung - can help. EU-funded[...]

World Diabetes Day - 14 November    uicc.org

Global Education and Training Initiative Global Access to Pain Relief Initiative Global Initiative for Cancer Registry Development Please contact UICC for any questions Act today, to change tomorrow[...]

The National Parkinson Foundation Launches CareMAP: An Online Guide to Caring for Someone with Advanced Parkinson's Disease    epda.eu.com

The National Parkinson Foundation (NPF) announced the launch of a new online guide, CareMAP, which provides practical suggestions for coping with the complex problems that arise as a result of advanc[...]

Formulations of hormone therapy and risk of Parkinson's disease    epda.eu.com

The findings from this study suggest an increase in PD risk associated with esterified estrogen use combined with progestin, and no risk associated with conjugated estrogen with progestin. These find[...]

Imaging prodromal Parkinson disease: The Parkinson Associated Risk Syndrome Study    epda.eu.com

Conclusion: Subjects with DAT deficit who do not meet criteria for a diagnosis of PD can be identified by olfactory testing. Sequential biomarker assessment may identify those at risk of PD.[...]

Global Kinetics Corporation Announces FDA Clearance of the Personal KinetiGraph™ for Assessment of Parkinson's Disease Symptoms    epda.eu.com

Global Kinetics Corporation, a leading mobile health technologies company, today announced that the U.S. Food and Drug Administration (FDA) has cleared the marketing of the company's Personal KinetiG[...]

The impact of subthalamic deep brain stimulation on caregivers of Parkinson's disease patients: an exploratory study    epda.eu.com

Study results show that at 1-year FU over 50 % of the caregivers rated their subjective well-being as negative. Especially older and more depressed caregivers are at risk. These caregivers and their [...]

Scientists create Parkinson's disease in a dish    epda.eu.com

A team of scientists led by The New York Stem Cell Foundation (NYSCF) Research Institute successfully created a human stem cell disease model of Parkinson's disease in a dish.[...]

KineMed Receives U.S. Patent Allowance for Noscapine to Treat ALS, Parkinson's Disease, and Diabetic Neuropathy    epda.eu.com

KineMed, Inc. today announced that the company has received a notice of allowance from the U.S. Patent and Trademark Office for the invention entitled: Compositions and Methods of Treatment Using Mod[...]

Parkinson's disease severity levels and MDS-Unified Parkinson's Disease Rating Scale    epda.eu.com

Scores of more detailed assessments, as the MDS-UPDRS, have not been translated to a grading that allows assignment of score sections to severity levels. The objective of the present study is to dete[...]

Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy & Potency to Fetal Neurons when Grafted in a Rat Model of P    epda.eu.com

Authors show long-term survival and functionality using clinically relevant MRI and PET imaging techniques and demonstrate efficacy in restoration of motor function with a potency comparable to that [...]

PRAC recommends measures to reduce risk of heart problems with Corlentor/Procoralan (ivabradine)    europa.eu

PRAC recommendations to be considered by CHMP for final opinion[...]

Parkinson's Disease Foundation Highlights Diverse Contributions of Care Partners    epda.eu.com

As part of National Family Caregivers Month this November, the Parkinson's Disease Foundation (PDF) recognizes the diverse contributions of loved ones of people with Parkinson's disease, with its All[...]

3D printed heart to be showcased at world’s largest cardiovascular imaging congress    escardio.org

Media alert: EuroEcho-Imaging 2014 will reveal state of the art technologies for choosing implants and guiding procedures and new frontiers in cardiovascular imaging will be explored through presenta[...]

Head injury, α-synuclein genetic variability and Parkinson's disease    epda.eu.com

The study finds some evidence that head injury and D4S3481 or rs356165 variants jointly increase the risk of PD but little evidence of interaction.[...]

Call for proposals: 'Global Alliance for Chronic Diseases. Prevention and treatment of lung diseases'    europa.eu

Research Participant Portal is your entry point for electronic administration of EU-funded research and innovation projects[...]

Jordan Breast Cancer Program 2014 Campaign launched    uicc.org

The King Hussein Cancer Foundation and Center (KHCF/KHCC) , a UICC Member, have been entrusted with the leadership of the Jordan Breast Cancer Program (JBCP) . Established in 2007 as a national prog[...]

Unprecedented multi-stakeholder Parkinson's disease initiative 'My PD Journey' aims to improve the lives of thousands people    epda.eu.com

The European Parkinson's Disease Association (EPDA) has launched a first-of-its-kind initiative for people with Parkinson's in Europe entitled My PD Journey.[...]

Unprecedented multi-stakeholder Parkinson's disease initiative 'My PD Journey' aims to improve the lives of thousands people    epda.eu.com

The European Parkinson's Disease Association (EPDA) has launched a first-of-its-kind initiative for people with Parkinson's in Europe entitled My PD Journey.[...]

The multi-stakeholder Parkinson's disease initiative 'My PD Journey' begins its first major research project to identify whe    epda.eu.com

The European Parkinson's Disease Association (EPDA) has launched a major research project across Europe to identify good practice and to seek out the major gaps in Parkinson's disease care that curre[...]

The multi-stakeholder Parkinson's disease initiative 'My PD Journey' begins its first major research project to identify whe    epda.eu.com

The European Parkinson's Disease Association (EPDA) has launched a major research project across Europe to identify good practice and to seek out the major gaps in Parkinson's disease care that curre[...]

How hot is your preventive cardiology knowledge? Take the new quiz!    escardio.org

Study the graphs and charts, answer the questions, check your response and learn more with the EACPR quizzes. Cardiopulmonary exercise stress test in bundle branch block (LBBB)Management of young ath[...]

[Save the date] Launch of a Research Roadmap for Liver Disease (HEPAMAP)    epha.org

MEP Christian Buşoi (EPP, RO) has the pleasure to invite you to the [...]

Midlife migraine and late-life parkinsonism    epda.eu.com

These findings suggest there may be a common vulnerability to, or consequences of, migraine and multiple indicators of parkinsonism. Additional genetic and longitudinal observational studies are need[...]

Mucuna pruriens mRescues Motor, Olfactory, Mitochondrial & Synaptic Impairment in PINK1B9 Drosophila melanogaster Genetic Model    epda.eu.com

Overall, this study strengthens the relevance of using PINK1B9 Dm as a translational model to study the properties of Mucuna pruriens for PD treatment.[...]

Akinetic-Rigid and Tremor-Dominant Parkinson's Disease Patients Show Different Patterns of Intrinsic Brain Activity    epda.eu.com

Overall, study findings highlight the involvement of default mode network (DMN) and STC circuit both in AR and TD subtypes, but also underscore the importance of integrating mesolimbic-striatal and C[...]

Research Headlines - New tests aim to detect breast and ovarian cancers earlier    europa.eu

The EU-funded project EPIFEMCARE is developing blood tests that could lead to the earlier detection of ovarian and breast cancers, fewer over-diagnoses of breast cancer and improved personalised care[...]

miRNA expression is highly sensitive to a drug therapy in Parkinson's disease    epda.eu.com

Conclusions: It is probable that miRNAs are very sensitive to drug therapy and that the effects of therapy observed may be associated with changes in the levels of these miRNAs and their target genes[...]

Dopamine transporter SLC6A3 genotype affects cortico-striatal activity of set-shifts in Parkinson's disease    epda.eu.com

This is the first study indicating that the SLC6A3/DAT1 genotype has a significant effect on fronto-striatal activation and performance in Parkinson's disease. This effect is stronger for conditions [...]

EU breast cancer research targets personalised treatment    europa.eu

European Commission Press release Brussels, 27 October 2014 Caption: The ASSURE project tailors breast cancer screening - hematoxylin and eosin marked breast tissue containing invasive ductal carcino[...]

Cerebrospinal fluid biochemical studies in patients with Parkinson's: towards a potential search for biomarkers for this disease    epda.eu.com

Cerebrospinal fluid (CSF) has been widely investigated in PD and in other parkinsonian syndromes with the aim of establishing useful biomarkers for an accurate differential diagnosis among these synd[...]

Alternations of Mean Diffusivity of Pedunculopontine Nucleus Pathway in Parkinson's Disease Patients with Freezing of Gait    epda.eu.com

Conclusions: Based on study results, microstructural changes of pedunculopontine nucleus and connected subcortical structures are closely related with FOG in PD patients.[...]

Research Headlines - New horizons in treating breast cancer    europa.eu

Today, in most developed countries, a woman s chance of getting breast cancer is 1 in 8. Clinical trials have shown that despite its effectiveness, chemotherapy can also cause long- term side-effects[...]

European Commission Initiative on Breast Cancer - Calls for expressions of interest    europa.eu

European Commission - The European Commission invites individual experts to join the working groups which will be established in the framework of the European Initiative on Breast Cancer:[...]

Lynparza recommended for approval in ovarian cancer    europa.eu

First-in-class medicine to provide new treatment option in patients with a BRCA mutation[...]

European Medicines Agency recommends further measures to minimise risk of blood vessel blockage with Iclusig    europa.eu

The European Medicines Agency (EMA) has concluded its review of the benefits and risks of Iclusig (ponatinib), a medicine used for the treatment of leukaemia (cancer of the white blood cells), and ha[...]

Research Headlines - New horizons in treating breast cancer    europa.eu

Today, in most developed countries, a woman s chance of getting breast cancer is 1 in 8. Clinical trials have shown that despite its effectiveness, chemotherapy can also cause long- term side-effects[...]

[Press release] The European Parliament will not gain people's trust by continuing to contribute to the burden of chronic disease in the form of tobacco subsidies    epha.org

Brussels, 23 October 2014 - Among all the furore yesterday of the new Commission, the European Parliament also quietly voted against ending EU subsidies to tobacco crops (1). While on the one hand ma[...]

How hot is your sports cardiology knowledge? Take the new quiz!    escardio.org

Management of young athletes with T-wave inversions[...]

Predictors of the psychosocial impact of being a carer of people living with Parkinson's disease: A systematic review    epda.eu.com

Confident conclusions could not be drawn regarding the most important predictors that should be targeted in psychosocial interventions due to methodological weaknesses and lack of theoretical testing[...]

The EPDA's My PD Journey Project starts work on a new Parkinson's disease Composite Quality of Life Scale    epda.eu.com

Work has begun to develop a new composite scale for motor and non-motor symptoms of Parkinson's disease.[...]

The EPDA's My PD Journey Project starts work on a new Parkinson's disease Composite Quality of Life Scale    epda.eu.com

Work has begun to develop a new composite scale for motor and non-motor symptoms of Parkinson's disease.[...]

Autonomic Dysfunction in Parkinson's Disease With and Without Deep Brain Stimulation    epda.eu.com

New findings from The Parkinson Alliance (PA) survey entitled Autonomic Dysfunction in Parkinson's Disease With and Without Deep Brain Stimulation show that autonomic dysfunction was highly prevalent[...]

Cerebrospinal fluid biomarkers in parkinsonian conditions: an update and future directions    epda.eu.com

In this review, several of the most promising cerebrospinal fluid candidate markers will be discussed. Their strengths and limitations will be considered together with future developments in the fiel[...]

Genetic impact on cognition and brain function in newly diagnosed Parkinson's disease: ICICLE-PD study    epda.eu.com

This study demonstrates that neurocognitive deficits are common even in recently diagnosed patients with Parkinson's disease, and that the associated regional brain activations are influenced by geno[...]

RES – Save the date! Hormone dependent cancer and EDCs    env-health.org

On 29 October Réseau Environnement Santé (RES) is hosting an event on hormone-dependent cancers and EDCs, sponsored by Mrs Chantal Jouanno, Senator of Paris. According to the International Agency for[...]

WECF – Conference on breast cancer, reproductive health and EDCs    env-health.org

Women in Europe for a Common Future (WECF) France successfully held their international conference on breast cancer, women's reproductive health and EDCs: from knowledge to prevention on 14 October. [...]

A Genetic Mouse Model of Parkinson's Disease Shows Involuntary Movements and Increased Postsynaptic Sensitivity to Apomorphine    epda.eu.com

Study results document for the first time a disturbance of ERK1/2 signaling regulation associated with apomorphine-induced involuntary movements in a genetic mouse model of synucleinopathy. This mous[...]

Parkinson's UK appoints Research Director to ignite industry collaboration    epda.eu.com

Parkinson's UK has appointed leading pharma industry expert Dr Arthur Roach as their Research Director in a bid to spearhead collaboration between Parkinson's medical research and industry.[...]

Structural MRI correlates of the MMSE and pentagon copying test in Parkinson's disease    epda.eu.com

Study results suggest MMSE and the pentagon item reflect brain changes which at a regional level involve mainly posterior regions. Correlates of the pentagon item were seen in the same regions where [...]

EHRA EUROPACE - CARDIOSTIM 2015: Submit your abstract    escardio.org

Be part of the top European electrophysiology congress in 2015 by submitting an abstract to EHRA EUROPACE - CARDIOSTIM 2015. Topics: Arrhythmias, Atrial Fibrillation[...]

Catechol-O-methyltransferase Val158Met polymorphism: Modulation of wearing-off susceptibility in a Chinese cohort of Parkinson's    epda.eu.com

The purpose of this study was to characterize the correlation between the Val158Met polymorphism in the COMT gene and the motor complication wearing-off in Chinese PD patients. Authors have sequenced[...]

Heart rate may predict survival and brain function in comatose cardiac arrest survivors    escardio.org

Study presented at Acute Cardiovascular Care 2014 by Dr Jakob Hartvig Thomsen from Denmark finds patients with sinus bradycardia during therapeutic hypothermia had a 50-60% lower mortality rate at 18[...]

Women more likely to develop anxiety and depression after heart attack    escardio.org

According to research presented at Acute Cardiovascular Care 2014 by Professor Pranas Serpytis from Lithuania: [...]

Vitamin D deficiency increases poor brain function after cardiac arrest by seven-fold    escardio.org

According to research presented at Acute Cardiovascular Care 2014 by Dr Jin Wi from Korea, patients with vitamin D deficiency were more likely to have a poor neurological outcome or die after sudden [...]

Welcome To Acute Cardiovascular Care 2014 in Geneva    escardio.org

We are pleased to welcome you to Acute Cardiovascular Care 2014! As you know, the theme of the third official congress of the Acute Cardiovascular Care Association will be [...]

ACCA Clinical Decision - Making Toolkit Mobile App    escardio.org

Immediate bedside decision now at your fingertips!Download and try Acute Coronary Syndromes and Acute Heart Failure! Topics: Acute Coronary Syndromes (ACS)[...]

Challenges in prevention: Reports from Lebanon and Egypt    escardio.org

Heart Failure 2015 / 2nd World Congress on Acute Heart Failure European Heart Journal - Acute Cardiovascular Care European Heart Journal - Cardiovascular Pharmacotherapy EHJ: Clinical Outcomes &[...]

European Code Against Cancer – Fourth edition    europa.eu

4th European Code Against Cancer launched today - Directorate General for Health & Consumers[...]

European Alcohol Policy Alliance warmly welcomes the New European Code Against Cancer    eurocare.org

The European Alcohol Policy Alliance (Eurocare) congratulates the International Agency for Research on Cancer (IARC) and the European Commission on the release of the updated 4th edition of the Europ[...]

New European code prescribes 12 ways to prevent cancer    who.int

Avoiding tobacco, alcohol and excessive sun exposure; maintaining a healthy body weight; and being physically active are among 12 ways to prevent cancer prescribed by the new European Code Against Ca[...]

Launch of new European Code Against Cancer    uicc.org

Based on the best available scientific evidence, the new Code provides 12 ways to adopt healthier lifestyles and boost cancer prevention across Europe. It is the outcome of a two-year collaborative [...]

[Press release] EPHA encourages policy makers to be braver when tackling the cancer epidemic in Europe    epha.org

14 October 2014, Brussels - The 4th edition of the European Code Against Cancer was finally launched today after many months of delay (1). As a member of the recently established Commission Expert Gr[...]

New cancer expert group: cancer is on the EU public health agenda    epha.org

On the first meeting of the new expert group on cancer, which was held on 22-23 September, the Commission presented an overview of the EU priorities for cancer and an implementation report on previou[...]

The Michael J. Fox Foundation and Intel join forces to improve Parkinson's disease monitoring and treatment through advanced tec    epda.eu.com

The Michael J. Fox Foundation for Parkinson's Research (MJFF) and Intel Corporation announced today a collaboration aimed at improving research and treatment for Parkinson's disease - a neurodegenera[...]

Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats    epda.eu.com

In conclusion, authors here provide the first experimental evidence that different α-synuclein forms can propagate from the gut to the brain, and that microtubule-associated transport is involved in [...]

Rotigotine vs ropinirole in advanced stage Parkinson's disease: A double-blind study    epda.eu.com

Conclusions: Rotigotine was well tolerated at doses up to 16 mg/24 h and showed similar efficacy to ropinirole except that the application site reaction was much higher in the rotigotine group.[...]

MRI brain scans detect people with early Parkinson's    epda.eu.com

Oxford University researchers have developed a simple and quick MRI technique that offers promise for early diagnosis of Parkinson's disease[...]

Lundbeck receives grant from The Michael J. Fox Foundation for biological markers identification in Parkinson's disease    epda.eu.com

A Lundbeck research program aiming to increase the knowledge of how a specific change in a gene (Lrrk2) contributes to an increased risk of developing Parkinson's disease was granted DKK 3,5m from Th[...]

International Parkinson's Empowerment Summit 2014    epda.eu.com

The Davis Phinney Foundation and Move4Parkinson's invite people living with Parkinson's, their families and care partners to join them for a unique, international event in Dublin, Ireland.[...]

NIH scientists find six new genetic risk factors for Parkinson's    epda.eu.com

Using data from over 18,000 patients, scientists have identified more than two dozen genetic risk factors involved in Parkinson's disease, including six that had not been previously reported. The stu[...]

First clinical data of therapeutic Parkinson's disease vaccine encourages continued development    epda.eu.com

AFFiRiS AG announced today at a press conference in New York results of AFF008, a Phase I clinical trial of PD01A, a vaccine against Parkinson´s disease. PD01A is the first therapy against the protei[...]

Imaging prodromal Parkinson disease: The Parkinson Associated Risk Syndrome Study    epda.eu.com

Conclusion: Subjects with DAT deficit who do not meet criteria for a diagnosis of PD can be identified by olfactory testing. Sequential biomarker assessment may identify those at risk of PD.[...]

PRAC review does not confirm increase in heart problems with testosterone medicines    europa.eu

Committee recommends medicines can continue to be given for their authorised uses[...]

PRAC recommends further measures to minimise risk of blood vessel blockage with Iclusig    europa.eu

PRAC recommendations to be considered by CHMP for final opinion[...]

Alliance for Cancer Prevention    env-health.org

Formed in 2009, the Alliance is a multi-stakeholder group which includes representatives from; NGOs, environmental and occupational health organisations, trade unions, public health advocates and civ[...]

Controversial fetal cell transplants revived for Parkinson's trials    epda.eu.com

For the last 25 years, using fetal tissue for scientific research has largely fallen out of favor in both the European and U.S. scientific communities. One of the most publicised uses of the controve[...]

New publication: WHO European Childhood Obesity Surveillance Initiative. Implementation of round 1 (2007/2008) and round 2 (2009/2010)    who.int

Disaster preparedness and response Haemophilus influenza (HiB) diseases Health 2020: the European policy for health and well-being Vector-borne and parasitic diseases The former Yugoslav Republic of[...]

Draft inventory of paediatric therapeutic needs: Paediatric oncology    europa.eu

Based on Article 43 of the European Union Paediatric Regulation the Paediatric Committee at the European Medicines Agency (PDCO) is working to establish an inventory to identify the needs in the diff[...]

Press release - “SIN List” advance will contribute to reducing chronic disease    env-health.org

Today, 28 more chemicals are being added to the SIN List of chemicals of [...]

Success Stories - Defining biomarkers to spot bladder cancer    europa.eu

The European FP7 project DeCanbio brought together a consortium of clinicians and researchers in genomics, proteomics and bioinformatics to identify and validate biomarkers that hint at a recurring b[...]

Combating obesity through national school food policies across Europe    eufic.org

Schools are regarded as a promising intervention target to counteract the increase of childhood obesity levels. In this context, the European Commission's Joint Research Centre (JRC) published a repo[...]

Brains in the balance: New $11.5M grant fuels University of Michigan Parkinson's disease research center to aid patients    epda.eu.com

NIH grant creates Udall Center of Excellence for Parkinson's Disease Research focused on developing a treatment to prevent falls.[...]

Parkinson's disease and age: The obvious but largely unexplored link    epda.eu.com

The risk of Parkinson's disease increases dramatically in individuals over the age of 60 and it is estimated that more than 1% of all seniors have some form of the condition. In this review, authors [...]

Distinct phenotypes of speech and voice disorders in Parkinson's disease after subthalamic nucleus deep brain stimulation    epda.eu.com

Conclusions: Stuttering and breathy voice can be aggravated by STN-DBS, but are mainly due to aging or PD itself. Strained voice and spastic dysarthria are considered corticobulbar side effects.[...]

ESC webinar: How to manage cardiovascular disease in the pre-diabetic patient?    escardio.org

On 28 October 2014 from 18:00 to 19:00 CET, join Nicolas Danchin and Ramzi Ajjan for a live streaming event on How to manage cardiovascular disease in the pre-diabetic patient? by 26 OctoberTopics: D[...]

Comparison of sleep and other non-motor symptoms between SWEDDs patients and de novo Parkinson´s disease patients    epda.eu.com

Conclusions: The patients with SWEDDs have less non-motor problems than newly diagnosed untreated PD patients. Given the difficulty distinguishing between SWEDDs and early PD, identifying some of non[...]

Suprathreshold odor intensity perception in early-stage Parkinson's disease    epda.eu.com

Conclusions: Parkinson's disease (PD) influences suprathreshold estimates of perceived odor intensity, negating the notion that such perception might be spared in this disease. No association with do[...]

Development and validation of a new screening questionnaire for dysphagia in early stages of Parkinson's disease    epda.eu.com

The two-phased project comprised the questionnaire, diagnostic scales construction (N=105), and a validation study (N=82). Data for the project were gathered from PD patients at a German Movement Dis[...]

Reduced thalamic volume in Parkinson Disease with REM Sleep Behavior Disorder: volumetric study    epda.eu.com

Study findings suggest that the presence of RBD symptoms in PD patients is associated with a reduced thalamic volume suggesting a pathophysiologic role of the thalamus in the complex circuit causing [...]

Flt3 ligand does not differentiate between Parkinsonian disorders    epda.eu.com

No validated biomarkers are available for early and accurate diagnosis of multiple system atrophy and other parkinsonian disorders. It has been reported that flt3 ligand levels in cerebrospinal fluid[...]

Stage-dependent nigral neuronal loss in incidental Lewy body and Parkinson's disease    epda.eu.com

In conclusion, study findings cast doubt on the pathogenic role of α-synuclein aggregates in elderly, but do suggest that the severity of neurodegeneration and local burden of α-synuclein pathologica[...]

High-frequency oscillations in Parkinson's disease: Spatial distribution and clinical relevance    epda.eu.com

Authors found a focal spatial distribution of high-frequency oscillations with highest power 2 mm below the dorsolateral border of the subthalamic nucleus. Within the subthalamic nucleus, power peake[...]

Natural history of falls in a population-based cohort of patients with Parkinson's disease: an 8-year prospective study    epda.eu.com

Nearly of the PD cohort reported falling after 8 years of follow-up. Disease-specific gait and axial impairments were the major risk factors for future falls in non-fallers at baseline. This has impl[...]

Chromosome 22q11.2 deletion may contain a locus for recessive early-onset Parkinson's disease    epda.eu.com

Herein, authors propose a hypothesis that it is not the microdeletion per se that is responsible for the phenotype but rather a complete loss of function of a gene within the region due to the combin[...]

Motor impairment, depression, dementia: Which forms the impression of disease severity in Parkinson's disease?    epda.eu.com

Conclusion: The additional burden of dementia and depression was underestimated in the CGIS rating, suggesting that they are possibly relativized against the motor impairment.[...]

Parkinson's UK and Global Kinetics Corporation collaborate to provide promising new mHealth technology throughout UK    epda.eu.com

An innovative medical device designed in Australia to improve management of Parkinson's is to be made available in services in the United Kingdom, as part of a 12-month pilot project.[...]

Risk of Parkinson's disease following severe constipation: A nationwide population-based cohort study    epda.eu.com

The association between constipation at the beginning of the study and the incidence of PD was examined using a Cox regression model. Information regarding comorbidities and concomitant medications u[...]

Today is World Heart Day!    uicc.org

Global Education and Training Initiative Global Access to Pain Relief Initiative Global Initiative for Cancer Registry Development Please contact UICC for any questions This World Heart Day, the Wor[...]

Formulations of hormone therapy and risk of Parkinson's disease    epda.eu.com

The findings from this study suggest an increase in PD risk associated with esterified estrogen use combined with progestin, and no risk associated with conjugated estrogen with progestin. These find[...]

Gait and balance in Parkinson's disease subtypes: objective measures and classification considerations    epda.eu.com

Clinical assessments of the disturbances seen in patients with the PIGD subtype are not consistent with objective measures; overlapping between the groups is seen in many objective features of gait a[...]

Impulse control disorder and rapid eye movement sleep behavior disorder in Parkinson's Disease    epda.eu.com

Conclusion: In Parkinson's disease, REM Sleep Behavior Disorder is not associated with impulse control disorder. The results of this study do not support the notion that PSG-confirmed RBD and ICD sha[...]

Try Something New This World Heart Day, urges the ESC    escardio.org

Heart disease is the leading cause of death worldwide, but it doesn't have to be. Reflecting on the World Heart Day theme, creating heart-healthy environments, ESC spokesperson Professor Stephan Giel[...]

Meeting highlights from the Committee for Medicinal Products for Human Use (CHMP) 22-25 September 2014    europa.eu

Fifteen new medicines and three extensions of indication recommended for approval[...]

WECF - Conference: Breast cancer, women's reproductive health and EDCs    env-health.org

On 14 October, Women in Europe for a Common Future (WECF) France are co-hosting an international conference on breast cancer, women's reproductive health and EDCs: from knowledge to prevention in Lyo[...]

First meeting of the Commission Expert Group on Cancer Control: 23-24 September 2014    europa.eu

First meeting of the Commission Expert Group on Cancer Control: 23-24 September 2014 - Directorate General for Health & Consumers[...]

Motor progression of Parkinson's disease with the leucine-rich repeat kinase 2 G2019S mutation    epda.eu.com

In this retrospective study, authors compared motor disease progression in Ashkenazi-Jewish (AJ) Parkinson's disease (PD) patients carrying the LRRK2*G2019S mutation with that of noncarriers.[...]

Subjective memory complaints, depressive symptoms and cognition in Parkinson's disease patients    epda.eu.com

Background and purpose: The goal of this study was to establish the prevalence of subjective memory complaints (SMCs) and depressive symptoms (DS)s and their relation to cognitive functioning in pati[...]

Apathy in untreated, de novo patients with Parkinson's disease: validation study of Apathy Evaluation Scale    epda.eu.com

The AES-S is a reliable and valid questionnaire for detecting apathy in PD. For screening purposes a 33/34 cut-off score is indicated, but a 38/39 cut-off score is necessary when a high specificity i[...]

Characterizing motor and non-motor aspects of early-morning off periods in Parkinson's: An international multicenter study    epda.eu.com

Results: The results demonstrate that EMO periods are common and occur in 59.7% of subjects across all disease stages in line with other reports. However, importantly, in 88.0% of those, EMOs were fo[...]

Cost of deep brain stimulation for the treatment of Parkinson's disease by surgical stimulation sites    epda.eu.com

Provider costs were similar for the 144 GPi and 130 STN patients (GPi: $138,044 vs. STN: $131,822; difference = $6,222, 95% confidence interval [CI]: $42,125 to $45,343). Societal costs were also sim[...]

Concomitant development of hypersexuality and delusional jealousy in patients with Parkinson's disease: A case series    epda.eu.com

Discussion: Hypersexuality and delusional jealousy may occur independently in PD patients on dopamine agonist therapy, but may develop together probably reflecting a common alteration of sexuality (s[...]

Does a specialist unit improve outcomes for hospitalized patients with Parkinson's disease?    epda.eu.com

The general ward care (n=20) and the Specialist Parkinson's Unit care (n=24) groups had similar baseline characteristics. On the specialist unit: less Parkinson's medication was omitted (13% v 20%, p[...]

Success Stories - Reducing the risk of Alzheimer's disease and vascular dementia - World Alzheimer Day 21-09-2014    europa.eu

Dementia is a group of degenerative diseases typically affecting the cognitive abilities of the elderly population. According to the World Health Organization, the estimated proportion of the general[...]

Dementia & severity of parkinsonism determines handicap of patients in late-stage Parkinson's: the BarcelonaLisbon cohort    epda.eu.com

Methods: Handicap, medical conditions, use of healthcare resources and the impact of LS-PD upon caregivers were characterized in a cross-sectional study of LS-PD stages 4 or 5 of Hoehn and Yahr (H&am[...]

World Cancer Day 2015: 'Not Beyond Us' Campaign launched!    uicc.org

World Cancer Day 2015: 'Not Beyond Us' Campaign launched! We have officially launched the 2015 World Cancer Day campaign We were thrilled that so many members, partners, stakeholders and supporters [...]

Cholinesterase inhibitors for Parkinson's disease: a systematic review and meta-analysis    epda.eu.com

Conclusions ChIs are effective in the treatment of cognitive impairment in patients with PD, but do not affect risk of falls. The choice of treatment has to be balanced considering the increased trem[...]

Back to the basics: regular exercise matters in Parkinson's: Results from the National Parkinson Foundation registry study    epda.eu.com

Regular exercisers at baseline was associated with better QOL, mobility, and physical function, less progression of disease, less caregiver burden and less cognitive decline one year later, after con[...]

Hippocampal volume and white matter disease in the prediction of dementia in Parkinson's disease    epda.eu.com

Conclusions: Hippocampal volume is a major factor predicting the development of mild cognitive impairment and dementia in PD. White matter hyperintensity also contributes to the longitudinal cognitiv[...]

Midlife migraine and late-life parkinsonism    epda.eu.com

These findings suggest there may be a common vulnerability to, or consequences of, migraine and multiple indicators of parkinsonism. Additional genetic and longitudinal observational studies are need[...]

EPDA Move for Change survey shows Parkinson's care standards are lagging just one in 10 patients are diagnosed by a disease ex    epda.eu.com

Care provision in Parkinson's disease is falling dismally short of the standards patients and carers have every right to expect, research across Europe indicates.[...]

The role of iron in brain ageing and neurodegenerative disorders    epda.eu.com

During ageing, different iron complexes accumulate in brain regions associated with motor and cognitive impairment. In various neurodegenerative diseases, such as Alzheimer's disease and Parkinson's [...]

Cardioscape reveals where the money for cardiovascular research in Europe comes from and what it is spent on    escardio.org

CVD is the number 1 killer in Europe claiming over 4 million lives in the Europe and 1.9 million lives per year in the European Union (EU). CVD is also estimated to cost the EU economy almost €196 bi[...]

Research Headlines - New hope for patients suffering from rare genetic disease    europa.eu

Very few of us have heard of Alpha-Mannosidosis. However, this rare genetic disease has affected the lives of hundreds of families across Europe and the world. Its first symptoms appear in early chil[...]

Prevalence of Malnutrition in Patients with Parkinson's: Comparative Study with Healthy Controls using MNA questionnaire    epda.eu.com

Study findings indicate the same nutritional status among mild to moderate PD patients compared with healthy controls. However, more than a quarter of the PD population was found to be at risk of mal[...]

Dopamine transporter SLC6A3 genotype affects cortico-striatal activity of set-shifts in Parkinson's disease    epda.eu.com

This is the first study indicating that the SLC6A3/DAT1 genotype has a significant effect on fronto-striatal activation and performance in Parkinson's disease. This effect is stronger for conditions [...]

Acupuncture on GB34 activates the precentral gyrus and prefrontal cortex in Parkinson's disease    epda.eu.com

Acupuncture stimulation on this acupoint activates the prefrontal cortex, precentral gyrus, and putamen in patients with PD; areas that are known to be impaired in patients with PD. Compared with hea[...]

Survey reveals knowledge gaps among Parkinson's patients and caregivers    epda.eu.com

A recent survey of more than 1,500 Parkinson's disease (PD) patients, caregivers and physicians reveals that information and specialized care can help patients become more engaged in their own treatm[...]

McCabe launches knowledge hub website    uicc.org

Global Education and Training Initiative Global Access to Pain Relief Initiative Global Initiative for Cancer Registry Development The McCabe Centre for Law and Cancer has recently launched an FCTC [...]

Mortality in Parkinson's disease is not associated with the severity of early dopaminergic defect    epda.eu.com

Results: Mortality rate was 56.8%. Although higher age (p 0.48).[...]

ACCA congress: Ensuring a rapid response to cardiac emergencies    escardio.org

Media Alert: Acute Cardiovascular Care 2014 is the event of the year for the latest science in the field and takes place 18-20 October in Geneva, Switzerland. Acute cardiovascular care is the special[...]

UICC & CACA team up for exciting new programme    uicc.org

UICC has signed an agreeement with CACA to develop a new fellowship programme. At the opening ceremony of the 8th Chinese Conference on Oncology in Jinan on September 12th, the Union for Internation[...]

UICC President awarded Gold Medal    uicc.org

Global Education and Training Initiative Global Access to Pain Relief Initiative Global Initiative for Cancer Registry Development From American Society of Therapeutic Radiation Oncology (ASTRO) Pro[...]

Canadian Study of Neurological Conditions Provides New Vital Information on the Impact of Parkinson's Disease    epda.eu.com

Parkinson Society Canada is excited to share today's release of the report on The National Population Health Study of Neurological Conditions by the Public Health Agency of Canada in partnership with[...]

Stimulation of the pedunculopontine nucleus area in Parkinson's disease: effects on speech and intelligibility    epda.eu.com

Although limited in this group of patients, speech impairment following pedunculopontine nucleus area stimulation is a possible outcome that should be considered before undertaking such surgery. Dele[...]

New ESC Guidelines on hypertrophic cardiomyopathy    escardio.org

The 2014 ESC Guidelines on the diagnosis and management of hypertrophic cardiomyopathy (HCM) are presented for the first time at this congress. The guidelines underscore the multidisciplinary approac[...]

Prof. J. RTC. Roelandt's obituary    escardio.org

Friends and ESC colleagues were deeply saddened to learn of the death of Professor Jos Roelandt, a former chairman of the ESC Working Group on Echocardiography (1976-82) and president of the Dutch So[...]

Far-reaching programme of ESC Registries    escardio.org

Since its introduction in 2008 the ESC's registry programme - known as the EURObservational Research Programme, or EORP - has grown from just two pilot surveys (both in heart failure) to a broad-rang[...]

ESC Awards 2014    escardio.org

Find out which were the winning presentations in each category: Young Investigator AwardsNursing/Allied Professional Investigator AwardChallenging Cases Report AwardModerated postersTop score posters[...]

ESC Congress 2014 'a resounding success'    escardio.org

'The ESC Congress has been a resounding success and I am proud of finishing my presidency on such a high note.' With these words, Prof Vardas said good bye to over 30 300 delegates who attended ESC C[...]

NEW: Donwload the EHRA Key Messages app    escardio.org

EHRA offers you now the possibility to get some of the reference scientific documents in your pockets, always with you. Download it now. Topics: Arrhythmias, Atrial Fibrillation, Sudden Cardiac Death[...]

Glucocerebrosidase mutations in primary parkinsonism    epda.eu.com

Conclusion: GBA dysfunction is relevant for synucleinopathies, such as PD and DLB, except for MSA, in which pathology involves oligodendrocytes, and the tauopathies PSP and CBD. The risk of developin[...]

Parkinson's Disease Foundation Announces Newest Series of Community-Driven Online Seminars    epda.eu.com

The Parkinson's Disease Foundation (PDF) is pleased to announce its sixth series of PD ExpertBriefings, free interactive seminars presented by leaders in Parkinson's disease research and care.[...]

Planning and developing population-based cancer registration in low- and middle-income settings (as an e-Book)    iarc.fr

Guidelines for establishing cancer registries, from the International Agency for Research on Cancer (IARC), the World Health Organization (WHO), and the International Association of Cancer Registries[...]

Stepping out for people with Parkinson's    epda.eu.com

With only a couple of weeks to go until the second European Unity Walk, we are all limbering up for what promises to be a hugely enjoyable and inspirational event.[...]

KineMed Receives U.S. Patent Allowance for Noscapine to Treat ALS, Parkinson's Disease, and Diabetic Neuropathy    epda.eu.com

KineMed, Inc. today announced that the company has received a notice of allowance from the U.S. Patent and Trademark Office for the invention entitled: Compositions and Methods of Treatment Using Mod[...]

Visual short-term memory deficits associated with GBA mutation and Parkinson's disease    epda.eu.com

These findings provide evidence for dissociable signature deficits within the domain of visual short-term memory associated with GBA mutation and with Parkinson's disease. Identification of the speci[...]

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