Directorate-General for Health and Food Safety
Major and chronic diseases
Project funded in 2004 - Strand 1: Health Information
Improving information and knowledge for the development of public healthArea of activity
Developing mechanisms for reporting and analysis of health issues and producing public health reportsSummary
ted morbidity have been recorded in some countries through active follow up. The EPIC data belong to the participating centres. The EPIC study is coordinated by IARC which has created the central EPIC databank and was responsible for the centralisation and standardization of selected data collected in the various countries during baseline recruitment. IARC is responsible for the creation and centralisation of the follow-up databank containing follow-up data and information on cancer incidence until December 2003, when the contract of EPIC officially ended. Some of these data have been already transferred to the EPIC Elderly database, stored in Athens for participants who were 60 years or over at recruitment.
The project will integrate all this information and create the EPIC-Elderly NAH databank with standardised baseline and follow up data on environmental determinants, self reported morbidity and cause specific mortality of European elders. An information database containing the results from systematic reviews of the relevant literature will also be created, to guide subsequent analyses. The cross-sectional and longitudinal associations of environmental determinants, including potential interactions, with morbidity and mortality in different age groups of elderly, as well as with changes in morbidity in a sub-sample of the EPIC-Elderly cohort, will be investigated. Targeted dissemination of the results will take place in the form of public health reports focussed on the determinants of healthy ageing, scientific papers, leaflets, a workshop and a website. The results' exploitation will lay a scientific and policy foundation for developing public health interventions in the important field of health care for the elderly.More info...
NKUA - National and Kapodistrian University of Athens
6 Chritou Lada Str.
- International Agency For Research On Cancer (IARC) established in Lyon, France
- Institut National de la Sante et de la Recherche Medicale (INSERM) - established in Paris, France (FR)
- Istituto Nazionale per lo Studio e la Cura dei Tumori (INSCT) - established in Milano, Italiy (IT)
- Universitair Medisch Centrum Utrecht (UMCU) - established in Utrecht, the Netherlands (NL)
- Deutsches Krebsforschungszentrum (DKFZ) - established in Heidelberg, Germany (DE)
- Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke (DIEF) - established in Potsdam, Germany (DE)
- Fundacion Vasca de Innovacion e Investigation Sanitarias (BIO) - established in .Sondika, Spain (ES)
- Kraeftens Bekaempelse (DCS) - established in Kobenhavn, Denmark (DK)
- UMEA Universitet (UMEA) - established in Umea, Sweden (SE)
date and duration of
- 36 months
Subsidy from the Commission
|Results to be achieved
Work package n° 1 - Coordination
- To coordinate six plenary meetings to take place during the three years duration of the project.
- To coordinate discussion on the definition of healthy ageing through age-related conditions
- To coordinate data transfer, data management and standardization activities for the creation of the expanded EPIC-Elderly database.
- To coordinate the accumulation of information on environmental predictors of healthy ageing for the subsequent analysis and create a relevant information database.
- To coordinate statistical analysis and writing of reports presenting results on the assessment of the health status of the EPIC-Elderly cohort and on the role of each of the examined determinants in healthy ageing.
- To prepare interim technical and financial reports for the Commission, which will review the work accomplished, the adherence to the time schedule and the allocation of the budget.
- To coordinate the writing of the final report for the Commission and scientific papers, as well as dissemination activities.
- To monitor the progress of tasks and facilitate the flow of the project work through the establishment of the monitoring team.
- To coordinate the four meetings of the monitoring team.
Work package n° 2 - Transfer, management and standardization of data
- To transfer the selected follow up data from the participating countries and IARC where appropriate to NKUA
- To transfer the selected baseline data from IARC to NKUA
- To harmonise all the transferred follow up data.
- To incorporate the follow-up and additional baseline data into the Epic-Elderly databank and create the EPIC-Elderly Network on Ageing and Health (EPIC-Elderly NAH) databank in the coordinating country.
Work package n° 3 - Statistical analysis and preparation of reports
- To undertake statistical analyses in order to present the age-related conditions used as indicators of healthy ageing and to investigate the cross-sectional and longitudinal associations of environmental determinants, including potential interactions, with morbidity and mortality in different age groups of elderly, as well as with changes in morbidity in a sub-sample of the EPIC-Elderly cohort.
- To prepare public health reports presenting results on the assessment of the health status of the EPIC-Elderly cohort and on the role of each of the examined determinants in healthy ageing.
Work package n° 4 - Dissemination
- To compile the final technical report to be presented to the Commission.
- To prepare scientific papers.
- Dissemination of the results.
- Strategic plan for using and disseminating the knowledge acquired in the context of the EPIC Elderly NAH project so that the continuation in the application of the acquired knowledge is secured upon conclusion of the project.
- Interim report (380KB)
of project aim(s) and
To set up a health information and surveillance programme for reporting issues relevant to ageing and health, by establishing a central databank of standardised data including baseline information on socio-demographic, dietary, lifestyle, somatometric characteristics and self reported morbidity, as well as follow up data on any of the above mentioned parameters and cause specific mortality of elderly Europeans.
To develop a mechanism of analysis of data related to ageing and health by applying appropriate methodology regarding the role of the indicated parameters and/or their interactions in healthy ageing, in order to identify potential environmental determinants of self-reported morbidity and mortality of elderly Europeans.
To prepare public health reports on the health status of a large cohort of Europeans aged 60 years or more, as well as on associated environmental determinants which can be used at the policy making level.
To disseminate through targeted activities, the results of the project.
To expand an existing databank on European elders, already including standardised baseline information on environmental parameters and self reported morbidity, with standardised follow up data on environmental parameters, morbidity and cause-specific mortality which have been collected on a national basis in 8 European countries, participating in EPIC and EPIC Elderly.
To set up an expert panel, which will deliver an information database on potential predictors of healthy ageing, by systematic reviews of the relevant literature.
To assess the health status of the ageing population in Europe (60 years or older) by means of age-related conditions such as cardiovascular diseases, diabetes, obesity, hypertension, hyperlipidaemia and cancer.
To investigate the cross-sectional and longitudinal associations of environmental data, including potential interactions, with morbidity and mortality in different age groups of elderly, as well as, with changes in morbidity.
To prepare public health reports focussing on determinants of healthy ageing for European elders, which could be used at the policy making level in the important field of health care for the elderly.
To compile the final report for the Commission which will summarise the methodology described above and will present comparable results on the above-indicated age-related conditions and of their determinants.
To disseminate the results of the study to the scientific community and the general public as well as to other interested bodies.
Data relevant to healthy ageing and its' determinants are sparse in Europe. In addition, between-country comparisons are hindered by differences in data collection, methodology and analytical strategies. This project will overcome these issues by expanding the established EPIC Elderly databank on standardized and centralised data on age-related conditions and their potential determinants with longitudinal information on the same variables. This new databank (EPIC Elderly NAH) will contain baseline and follow up data for the largest pan-European cohort of about 100000 European elders.
Potential risks that may hinder the work are delays in data transfer and management, in reviewing the literature and in reporting the results. For the correct and timely fulfilment of the aims of the project, the progress of each workpackage will be closely monitored by a monitoring team. The project's Consortium, which includes a team of experts in various fields who have successfully co-operated in previous major projects utilizing data from the same cohort (EPIC, EPIC-Elderly), further assures the effective resolution of problems encountered during the project's lifetime.