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Community Register of medicinal products

Register of not active Orphan Medicinal Products (by number)

EU Designation Product Designated Orphan Indication Sponsor Designation date Tradename
EU Centralised Nr
implemented by
EU/3/00/002 Alpha-Galactosidase A Treatment of Fabry disease Shire Human Genetic Therapies AB 8/08/2000 Replagal
EU/1/01/189/...
3/08/2001
EU/3/00/003 Alpha-Galactosidase A Treatment of Fabry disease Genzyme Europe B.V. 8/08/2000 Fabrazyme
EU/1/01/188/...
3/08/2001
EU/3/00/004 Fluorouracil Treatment of glioblastoma Ethypharm S.A. 18/10/2000
EU/3/00/008 Arsenic trioxide Treatment of acute promyelocytic leukaemia Cephalon Europe 18/10/2000 Trisenox
EU/1/02/204/...
5/03/2002
EU/3/00/009 Thalidomide Treatment of erythema nodosum leprosum (ENL) or type II lepra reactions Pharmion France 29/12/2000
EU/3/00/015 Xaliproden hydrochloride Treatment of amyotrophic lateral sclerosis SANOFI 17/01/2001
EU/3/00/016 Lusupultide Treatment of acute respiratory distress syndrome Nycomed GmbH 17/01/2001
EU/3/00/017 Arsenic trioxide Treatment of acute promyelocytic leukaemia Agence générale des équipements et produits de santé - Etablissement pharmaceutique des hôpitaux de Paris (AGEPS-EPHP) 17/01/2001
EU/3/01/021 Imatinib mesylate Treatment of chronic myeloid leukaemia Novartis Europharm Ltd 14/02/2001 Glivec
EU/1/01/198/...
7/11/2001
EU/3/01/024 Ribavirin Treatment of haemorrhagic fever with renal syndrome ICN Pharmaceuticals Limited 14/02/2001
EU/3/01/027 Ibuprofen Prevention of patent ductus arteriosus in premature neonates of less than 34 weeks of gestational age Orphan Europe S.a.r.l. 5/03/2001
EU/3/01/029 Ribavirin Treatment of adenovirus infection in immunocompromised patients Valeant Pharmaceuticals Limited 8/03/2001
EU/3/01/030 8-cyclopentlyl-1,3-dipropylxanthine Treatment of cystic fibrosis SciClone Pharmaceuticals Italy S.r.l 29/03/2001
EU/3/01/031 Arsenic trioxide Treatment of myelodysplastic syndromes Cephalon Europe 29/03/2001
EU/3/01/032 Arsenic trioxide Treatment of multiple myeloma Cephalon Europe 29/03/2001
EU/3/01/033 Ranpirnase Treatment of malignant mesothelioma MoRa Pharma GmbH 29/03/2001
EU/3/01/036 Recombinant human C1-inhibitor Treatment of angioedema caused by C1 inhibitor deficiency Pharming Group N.V. 11/05/2001
EU/3/01/037 Humanised Anti-HM1.24 Monoclonal Antibody Treatment of multiple myeloma Chugai Pharma Europe Ltd 10/05/2001
EU/3/01/040 Fomepizole Treatment of methanol poisoning IDIS Ltd 30/05/2001
EU/3/01/041 Recombinant human alpha-1-antitrypsin (respiratory use) Treatment of emphysema secondary to congenital alpha 1-antitrypsin deficiency Bayer HealthCare AG 30/05/2001
EU/3/01/042 Human engineered monoclonal antibody specific for Transforming Growth Factor ß2 Prevention of scarring in glaucoma filtration surgical procedures Cambridge Antibody Technology 30/05/2001
EU/3/01/043 Human Milk Fat Globule 1 / Human Milk Fat Globule 1 - S-p-isothiocyanatobenzyl-diethylenetriaminepentaacetic acid for use with 90Yttrium Treatment of ovarian cancer Antisoma Plc 30/05/2001
EU/3/01/046 Thalidomide Treatment of Graft versus Host Disease Pharmion France 9/07/2001
EU/3/01/047 Thalidomide Treatment of multiple myeloma Pharmion France 9/07/2001
EU/3/01/052 Seocalcitol Treatment of hepatocellular carcinoma Leo Pharmaceutical Products 31/07/2001
EU/3/01/053 Beraprost sodium Treatment of pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension Aventis Pharma S.A. 18/09/2001
EU/3/01/054 Sinapultide, dipalmitoylfosfatidylcholine, palmitoyloleoyl fosfatidylglycerol and palmitic acid Treatment of Meconium Aspiration Syndrome Discovery Laboratories, Inc 19/09/2001
EU/3/01/057 Porcine lung surfactant Treatment of acute lung injury Leo Pharmaceutical Products 19/09/2001
EU/3/01/060 Pemetrexed disodium Treatment of malignant mesothelioma Eli Lilly Nederland BV 17/09/2001
EU/3/01/061 Imatinib Treatment of malignant gastrointestinal stromal tumours Novartis Europharm Limited 20/11/2001 Glivec
EU/1/01/198/...
24/05/2002
EU/3/01/064 Abetimus sodium Treatment of lupus nephritis La Jolla Limited 20/11/2001
EU/3/01/066 Thalidomide Treatment of erythema nodosum leprosum (ENL) or type II lepra reactions Celgene Europe Limited 20/11/2001
EU/3/01/068 Thalidomide Treatment of multiple myeloma Kendle International Ltd 19/12/2001
EU/3/01/072 Apomorphine (oromucosal use) Treatment of off-periods in Parkinson´s disease not responding to other oral treatment Orion Corporation 5/12/2001
EU/3/01/073 Recombinant human monoclonal antibody to hsp90 Treatment of invasive fungal infections Novartis Europharm Ltd 5/12/2001
EU/3/01/076 Octovalent Pseudomonas aeruginosa O-polysaccharie-toxin A conjugate vaccine Prevention of Pseudomonas aeruginosa infections in patients with cystic fibrosis Orphan Europe S.a.r.l. 11/12/2001
EU/3/01/080 Human engineered monoclonal antibody specific for Transforming Growth Factor ß1 Treatment of systemic sclerosis Genzyme Europe B.V. 4/02/2002
EU/3/02/085 Carmustine (solution for intratumoral injection) Treatment of glioma Icon Clinical Research UK Ltd 5/03/2002
EU/3/02/087 Eflornithine hydrochloride Treatment of Familial Adenomatous Polyposis (FAP) ILEX Services Limited 19/02/2002
EU/3/02/088 Colistimethate sodium Treatment of Pseudomonas aeruginosa lung infection (including colonisation) in cystic fibrosis Forest Laboratories UK Ltd 19/02/2002
EU/3/02/089 GM-CSF receptor antagonist Treatment of juvenile myelomonocytic leukaemia British Biotech Pharmaceuticals Ltd 18/03/2002
EU/3/02/090 Human transferrin conjugated to mutant diphtheria toxin Treatment of gliomas Xenova Biomedix Limited 19/03/2002
EU/3/02/097 Humanized anti-KSA monoclonal antibody - human interleukin-2 fusion protein Treatment of renal cell carcinoma Merck KGaA 22/03/2002
EU/3/02/098 Epothilone B Treatment of ovarian cancer Novartis Europharm Ltd 22/03/2002
EU/3/02/099 Bryostatin-1 Treatment of oesophageal cancer GPC Biotech AG 30/04/2002
EU/3/02/100 Recombinant human alpha-1 antitrypsin Treatment of emphysema secondary to congenital alpha-1-antitrypsin deficiency Aptiv Solutions (UK) Ltd 30/04/2002
EU/3/02/105 Carbamic acid, [[4-[[3-[[4-[1-(4-hydroxyphenyl)-1-methyl-ethyl]phenoxy]methyl]phenyl]methoxy]-phenyl]iminomethyl]-,ethyl ester Treatment of cystic fibrosis Boehringer Ingelheim International GmbH 26/06/2002
EU/3/02/108 Myristoylated-peptidyl-recombinant SCR1-3 of human complement receptor type I Prevention of post transplantation graft dysfunction Orexo AB 30/07/2002
EU/3/02/112 Doxorubicin carbon / iron magnetically targeted microparticles Treatment of hepatocellular carcinoma Interface International Consultancy Limited 11/09/2002
EU/3/02/113 Mitotane Treatment of adrenal cortical carcinoma Agence générale des équipements et produits de santé - Etablissement pharmaceutique des hôpitaux de Paris (AGEPS-EPHP) 11/09/2002
EU/3/02/114 Myristoylated-peptidyl-recombinant Human CD59 Treatment of paroxysmal nocturnal haemoglubinuria Orexo AB 11/09/2002
EU/3/02/117 Boswellia serrata resin extract Treatment of peritumoral oedema derived from brain tumours Pharmasan GmbH 21/10/2002
EU/3/02/123 anti-CD147 murine monoclonal IgM Treatment of Graft versus Host Disease SangStat UK Limited 14/11/2002
EU/3/02/125 Monoclonal antibody to human interleukin-6 Treatment of post-transplant lymphoproliferative disorders EUSA Pharma SAS 18/12/2002
EU/3/02/131 Sodium oxybate Treatment of narcolepsy UCB Pharma Ltd. 3/02/2003 Xyrem
EU/1/05/312/...
13/10/2005
EU/3/03/138 a -1-acid glycoprotein Treatment of tricyclic antidepressants poisoning Bio Products Laboratory 20/03/2003
EU/3/03/142 Iodine (131I) anti-CEA sheep-human chimeric monoclonal antibody monoclonal antibody labeled with iodine-131 Treatment of pancreatic cancer Xenova Biomedix Limited 7/05/2003
EU/3/03/143 5-10-Methylene-tetrahydrofolate Treatment of pancreatic cancer in combination with 5-fluorouracil Interface International Consultancy Limited 11/06/2003
EU/3/03/146 Aldesleukin (inhalation use) Treatment of renal cell carcinoma Chiron Corporation Ltd 30/06/2003
EU/3/03/147 Amiloride hydrochloride dihydrate Treatment of cystic fibrosis Pulmo Tec GmbH 30/06/2003
EU/3/03/148 Chimeric-anti-interleukin-6 monoclonal antibody Treatment of renal cell carcinoma Janssen Biologics B.V. 30/06/2003
EU/3/03/150 5-methyl-pyridine-2-sulfonic acid {6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-[2-(1H-tetrazol-5-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide sodium salt Treatment of cutaneous T-cell lymphoma Transgene S.A. 9/07/2003
EU/3/03/151 Aplidine Treatment of acute lymphoblastic leukaemia Pharma Mar SA Sociedad Unipersonal 9/07/2003
EU/3/03/152 Engineered protein inhibitor of human neutrophil elastase Treatment of cystic fibrosis Debioclinic SA 9/07/2003
EU/3/03/158 Recombinant human arylsulfatase A Treatment of metachromatic leukodystrophy Shire Pharmaceuticals Ireland Limited 9/07/2003
EU/3/03/159 Recombinant human insulin-like growth factor-I / recombinant human insulin-like growth factor binding protein-3 Treatment of primary growth hormone insensitivity syndrome (Laron Syndrome) Insmed Europe Ltd 9/07/2003
EU/3/03/164 a-1-acid glycoprotein Treatment of cocaine poisoning Bio Products Laboratory 2/10/2003
EU/3/03/165 Nolatrexed Treatment of hepatocellular carcinoma Scirex Ltd. 2/10/2003
EU/3/03/167 H-Tyrosine-Glycine-Phenylalanine-Glycine-Glycine-OH Treatment of chronic idiopathic myelofibrosis Abiogen Pharma S.p.A. 20/10/2003
EU/3/03/180 4,5-dihydro-2-(2,4-dihydroxyphenyl)-4-methylthiazole-4(S)-carboxylic acid Treatment of chronic iron overload requiring chelation therapy Genzyme Europe B.V. 12/12/2003
EU/3/03/181 N-acetylsarcosyl-glycyl-L-valyl-D-allo-isoleucyl-L-threonyl-L-norvalyl-L-isoleucyl-L-arginyl-L-prolyl-N-ethylamide Treatment of soft tissue sarcoma Abbott International European Office 12/12/2003
EU/3/03/185 Tacrolimus hydrate Treatment of vernal keratoconjunctivitis Sucampo Pharma Europa Ltd 14/01/2004
EU/3/04/187 Human monoclonal hepatitis B immunoglobulins Prevention of hepatitis B re-infection following liver transplantation ICON Clinical Research (UK) Ltd 23/02/2004
EU/3/04/196 Ciclosporin Treatment of atopic keratoconjunctivitis Allergan Pharmaceuticals Ireland 14/04/2004
EU/3/04/218 (R, S)-3-(bromomethyl)-3-butanol-1-yl-diphosphate Treatment of renal cell carcinoma Innate Pharma SAS 29/07/2004
EU/3/04/221 5,10-methylene-tetrahydrofolic acid Treatment of pancreatic cancer in combination with 5-fluorouracil Interface International Consultancy Limited 2/09/2004
EU/3/04/225 Sodium dichloroacetate Treatment of systemic monochloroacetate poisoning Dr Anthony W. Fox 2/09/2004
EU/3/04/235 Recombinant human insulin-like growth factor-I / recombinant human insulin-like growth factor binding protein-3 Treatment of Type B extreme insulin resistance syndrome Insmed Europe Ltd 20/10/2004
EU/3/04/236 Recombinant human insulin-like growth factor-I / recombinant human insulin-like growth factor binding protein-3 Treatment of Type A extreme insulin resistance syndrome Dr Geoffrey Allan 21/10/2004
EU/3/04/237 Recombinant human insulin-like growth factor-I / recombinant human insulin-like growth factor binding protein-3 Treatment of Rabson-Mendenhall syndrome Dr Geoffrey Allan 21/10/2004
EU/3/04/238 Recombinant human insulin-like growth factor-I / recombinant human insulin-like growth factor binding protein-3 Treatment of Leprechaunism Insmed Europe Ltd 21/10/2004
EU/3/04/239 Deuterium oxide Treatment of pancreatic cancer BDD Berolina Drug Development GmbH 20/10/2004
EU/3/04/247 17-allylamino-17-demethoxygeldanamycin Treatment of multiple myeloma Bristol-Myers Squibb International Corporation 21/12/2004
EU/3/04/252 Val-Leu-Gln-Glu-Leu-Asn-Val-Thr-Val (Pr1 nanopeptide, sequence 169-177, of proteinase 3) Treatment of chronic myeloid leukemia Accelsiors CRO & Consultancy Services GmbH 21/12/2004
EU/3/04/253 Val-Leu-Gln-Glu-Leu-Asn-Val-Thr-Val (Pr1 nanopeptide, sequence 169-177, of proteinase 3) Treatment of acute myeloid leukaemia Accelsiors CRO & Consultancy Services GmbH 21/12/2004
EU/3/04/254 Val-Leu-Gln-Glu-Leu-Asn-Val-Thr-Val (Pr1 nanopeptide, sequence 169-177, of proteinase 3) Treatment of myelodysplastic syndromes Accelsiors CRO & Consultancy Services GmbH 21/12/2004
EU/3/04/255 Sabarubicin Treatment of small cell lung cancer Menarini Ricerche S.p.A. 21/12/2004
EU/3/04/256 17-allylamino-17-demethoxygeldanamycin Treatment of chronic myeloid leukemia Bristol-Myers Squibb International Corporation 26/01/2005
EU/3/04/259 Acetylcysteine Treatment of idiopathic pulmonary fibrosis Zambon Group Spa 26/01/2005
EU/3/05/267 (Z)-N-[2-(Diethylamino)ethyl]-5-[(5-fluoro-2-oxo-1,2-dihydro-3Hindol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (S)-2-hydroxysuccinate Treatment of malignant gastrointestinal stromal tumours Pfizer Ltd 10/03/2005 Sutent
EU/1/06/347/...
11/01/2007
EU/3/05/268 (Z)-N-[2-(Diethylamino)ethyl]-5-[(5-fluoro-2-oxo-1,2-dihydro-3Hindol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (S)-2-hydroxysuccinate Treatment of renal cell carcinoma Pfizer Ltd 10/03/2005
EU/3/05/271 Paromomycin sulphate Treatment of visceral leishmaniasis Sestria Ltd 11/04/2005
EU/3/05/281 Interferon gamma Treatment of idiopathic pulmonary fibrosis InterMune Europe Ltd 27/05/2005
EU/3/05/291 Human monoclonal antibody against HLA-DR Treatment of Hodgkin’s lymphoma GPC Biotech AG 16/06/2005
EU/3/05/304 Imatinib mesilate Treatment of acute lymphoblastic leukaemia Novartis Europharm Ltd 26/08/2005 Glivec
EU/1/01/198/...
13/09/2006
EU/3/05/305 Imatinib mesilate Treatment of dermatofibrosarcoma protuberans Novartis Europharm Ltd 26/08/2005 Glivec
EU/1/01/198/...
13/09/2006
EU/3/05/306 Imatinib mesilate Treatment of mastocytosis Novartis Europharm Ltd 26/08/2005
EU/3/05/308 Sapropterin Treatment of hyperphenylalaninemia Dr Gunter Schaub 26/08/2005
EU/3/05/309 Sodium valproate Treatement of 5q muscular atrophy The Jennifer Trust for Spinal Muscular Atrophy 26/08/2005
EU/3/05/311 Troxacitabine Treatment of acute myeloid leukaemia Pharm Research Associates (UK) Limited 26/08/2005
EU/3/05/320 Imatinib mesilate Treatment of chronic eosinophilic leukaemia and the hypereosinophilic syndrome Novartis Europharm Ltd 28/10/2005 Glivec
EU/1/01/198/...
28/11/2006
EU/3/05/322 Alfimeprase Treatment of acute peripheral arterial occlusion Quadramed Limited 28/10/2005
EU/3/05/330 Tilarginine acetate Treatment of cardiogenic shock Dr Ulrich Granzer 18/10/2005
EU/3/05/335 Human Staphylococcus aureus polyclonal immunoglobulin and human Staphylococcus epidermidis polyclonal immunoglobulin Prevention of late onset sepsis in premature infants of less or equal than 32 weeks gestational age Omnicare Clinical Research 14/12/2005
EU/3/05/340 Imatinib mesilate Treatment of myelodysplastic / myeloproliferative diseases Novartis Europharm Ltd 23/12/2005 Glivec
EU/1/01/198/...
28/11/2006
EU/3/05/344 vandetanib Treatment of medullary thyroid carcinoma AstraZeneca UK Limited 24/01/2006
EU/3/05/347 Human monoclonal antibody against HLA-DR Treatment of chronic lymphocytic leukaemia GPC Biotech AG 24/01/2006
EU/3/05/348 Purified inactivated Japanese encephalitis SA14-4-2 virus vaccine Prevention of Japanese encephalitis Intercell AG 24/01/2006 Ixiaro
EU/1/08/501/...
31/03/2009
EU/3/06/352 26 base single stranded phosphodiester DNA oligonucleotide Treatment of pancreatic cancer Antisoma Research Ltd 16/02/2006
EU/3/06/353 26 base single stranded phosphodiester DNA oligonucleotide Treatment of renal cell carcinoma Antisoma Research Ltd 16/02/2006
EU/3/06/357 2’-O-methyl-phosphorothioate oligonucleotide Treatment of Duchenne muscular dystrophy Prosensa B.V. 16/02/2006
EU/3/06/358 Human monoclonal antibody against HLA-DR Treatment of multiple myeloma GPC Biotech AG 28/02/2006
EU/3/06/377 Mecasermin rinfabate Treatment of patients with growth hormone (GH) gene deletion who have developed neutralizing antibodies to GH Insmed Europe Ltd. 20/06/2006
EU/3/06/378 Mecasermin rinfabate Treatment of primary insulin-like growth factor-1 deficiency due to molecular or genetic defects Insmed Europe Ltd. 20/06/2006
EU/3/06/382 Pazopanib hydrochloride Treatment of renal cell carcinoma Glaxo Group Limited 29/06/2006
EU/3/06/385 2-(4-(diethylamino) phenyl)-6-methyl-2H-benzo[d][1,2,3] triazol-5-amine Treatment of Duchenne muscular dystrophy Vastox plc. 25/07/2006
EU/3/06/393 Autologous CD34+ cells transfected with retroviral vector containing the human gp91(phox) gene Treatment of chronic granulomatous disease Vision 7 GmbH 28/08/2006
EU/3/06/398 H-Val-Ile-Val-Lys-Leu-Ile-Pro-Ser-Thr-Ser-Ser-Ala-Val-Asp-Thr-Pro-Tyr-Leu-Asp-Ile-Thr-Tyr-His-Phe-Val-Ala-Gln-Arg-Leu-Pro-Leu-OH Treatment of myasthenia gravis Debioclinic SA 28/08/2006
EU/3/06/402 Opebacan Treatment of meningococcal disease XOMA Ireland Ltd 28/08/2006
EU/3/06/415 Ciclosporin (implant) Prevention of rejection of corneal transplant Lux Biosciences GmbH 3/11/2006
EU/3/06/426 Fenretinide Treatment of primary malignant bone tumours Cancer Research UK 26/01/2007
EU/3/06/427 Fenretinide Treatment of soft tissue sarcoma Cancer Research UK 30/01/2007
EU/3/07/436 Eptacog alfa (activated) Treatment of post-neonatal intracerebral haemorrhage Novo Nordisk A/S 20/03/2007
EU/3/07/439 Recombinant human monoclonal antibody to human IL-1beta of the IgG1/K class Treatment of cryopirin-associated periodic syndromes (Familial Cold Urticaria Syndrome (FCUS), Muckle-Wells Syndrome (MWS), and Neonatal Onset Multisystem Inflammatory Disease (NOMID), also known as Chronic Infantile Neurological Cutaneous Novartis Europharm Ltd 20/03/2007 Ilaris
EU/1/09/564/...
23/10/2009
EU/3/07/449 everolimus Treatment of renal cell carcinoma Novartis Europharm Ltd 5/06/2007 Afinitor
EU/1/09/538/...
3/08/2009
EU/3/07/454 Recombinant adeno-associated viral vector containing human acid alpha-glucosidase-gene Treatment of glycogen storage disease type II (Pompe's disease) TMC Pharma Services Ltd. 9/07/2007
EU/3/07/457 Lusupultide Treatment of aspiration pneumonitis requiring intubation and mechanical ventilation Nycomed GmbH 10/07/2007
EU/3/07/460 Arsenic trioxide Treatment of acute myeloid leukaemia Cephalon Europe 2/08/2007
EU/3/07/464 Panobinostat lactate Treatment of cutaneous T-cell lymphoma Novartis Europharm Ltd 2/08/2007
EU/3/07/467 Eltrombopag olamine Treatment of idiopathic thrombocytopenic purpura GlaxoSmithKline Trading Services Limited 3/08/2007 Revolade
EU/1/10/612/...
11/03/2010
EU/3/07/468 Dihydroartemisinin, piperaquine Treatment of malaria Sigma Tau Industrie Farmaceutiche Riunite S.p.A 3/08/2007
EU/3/07/482 Sulfonated monophosphorylated mannose oligosaccharide Treatment of hepatocellular carcinoma Constella Group Ltd 14/09/2007
EU/3/07/483 Amonafide L-malate Treatment of acute myeloid leukaemia Antisoma Research Limited 22/10/2007
EU/3/07/488 everolimus Treatment of gastro-entero-pancreatic neuroendocrine tumours Novartis Europharm Ltd 14/11/2007
EU/3/07/497 4-[3,5-bis(trimethylsilyl)benzamido] benzoic acid Treatment of hepatocellular carcinoma Quintiles Ireland Ltd 22/10/2007
EU/3/07/512 17-(allylamino)-17-demethoxygeldanamycin hydroquinone hydrochloride Treatment of malignant gastro intestinal stromal tumours Voisin Consulting S.A.R.L. 29/11/2007
EU/3/07/515 Tegafur / gimeracil / oteracil Treatment of gastric cancer Taiho Pharma Europe Limited 20/12/2007
EU/3/08/527 Recombinant human monoclonal antibody to human IL-1beta of the IgG1/K class Treatment of systemic-onset juvenile idiopathic arthritis Novartis Europharm Ltd 4/02/2008
EU/3/08/528 Lumiliximab Treatment of chronic lymphocytic leukaemia Biogen Idec Limited 4/02/2008
EU/3/08/534 Allogeneic human umbilical cord tissue-derived cells Treatment of retinitis pigmentosa Centocor, B.V. 1/04/2008
EU/3/08/537 Autologous urothelial and smooth muscle cells Treatment of spina bifida European Medical Advisory Services Limited 17/03/2008
EU/3/08/547 Anti-von Willebrand Aptamer Treatment of thrombotic thrombocytopenic purpura FGK Representative Service GmbH 3/06/2008
EU/3/08/574 Autologous urothelial and smooth muscle cells Treatment of spinal cord injury European Medical Advisory Services Limited 7/11/2008
EU/3/08/606 Recombinant human residue 41 glutamic acid to glutamine variant of Interferon-alfa-2b Treatment of Behçet's disease Creabilis Therapeutics S.p.A. 19/01/2009
EU/3/09/626 Lintuzumab Treatment of myelodysplastic syndromes Seattle Genetics UK Limited 29/04/2009
EU/3/09/627 Lintuzumab Treatment of acute myeloid leukaemia Seattle Genetics UK Limited 30/04/2009
EU/3/09/631 Talampanel Treatment of glioma Teva Pharma GmbH 29/04/2009
EU/3/09/644 Murine monoclonal antibody to GD2 Treatment of neuroblastoma United Therapeutics Europe Ltd 12/06/2009
EU/3/09/646 Talampanel Treatment of amyotrophic lateral sclerosis Teva Pharma GmbH 12/06/2009
EU/3/09/662 26 base single stranded phosphodiester DNA oligonucleotide Treatment of acute myeloid leukaemia Antisoma Research Ltd 8/10/2009
EU/3/09/668 Human C1-inhibitor Treatment of angioedema caused by C1-inhibitor deficiency ViroPharma SPRL 8/10/2009
EU/3/09/678 (-)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1yl)-4-(1H-indol-3-yl) pyrrolidine-2, 5-dione Treatment of soft tissue sarcoma Gregory Fryer Associates Ltd 8/10/2009
EU/3/09/682 Anti-EphA2 monoclonal antibody conjugated to maleimidocaproyl monomethylauristatin phenylalanine Treatment of ovarian cancer MedImmune Ltd 28/10/2009
EU/3/09/687 Patupilone Treatment of primary peritoneal cancer Novartis Europharm Ltd 5/11/2009
EU/3/09/688 Patupilone Treatment of fallopian tube cancer Novartis Europharm Ltd 5/11/2009
EU/3/09/714 Streptococcus pyogenes Su strain cells treated with benzylpenicillin Treatment of congenital lymphatic malformations Theradex (Europe) Ltd. 29/01/2010
EU/3/09/721 Panobinostat Treatment of Hodgkin's lymphoma Novartis Europharm Ltd 2/02/2010
EU/3/09/722 Pixantrone dimaleate Treatment of diffuse large B-cell lymphoma CTI Life Sciences Ltd 2/02/2010
EU/3/10/729 (1S, 2S, 3R, 4R)-3-(5-Fluoro-2-(3-methyl-4-(4-methylpiperazin-1-yl)-phenylamino)-pyrimidin-4-ylamino)-bicyclo[2.2.1]hept-5-ene-2-carboxamide benzoate Treatment of acute myeloid leukaemia Merck KGaA 23/03/2010
EU/3/10/743 Pagibaximab Prevention of sepsis caused by Gram positive pathogens in premature infants less than or equal to 34 weeks of gestational age Theorem Clinical Research GmbH 9/06/2010
EU/3/10/763 Dexamethasone (intravitreal implant) Treatment of non-infectious uveitis affecting the posterior segment of the eye Allergan Pharmaceuticals Ireland 4/08/2010
EU/3/10/790 Ambrisentan Treatment of idiopathic pulmonary fibrosis Gilead Sciences International Ltd 1/10/2010
EU/3/10/837 Plitidepsin Treatment of primary myelofibrosis Pharma Mar S.A. Sociedad Unipersonal 23/02/2011
EU/3/10/838 Plitidepsin Treatment of post-essential thrombocythaemia myelofibrosis Pharma Mar S.A. Sociedad Unipersonal 23/02/2011
EU/3/10/839 Plitidepsin Treatment of post-polycythaemia vera myelofibrosis Pharma Mar S.A. Sociedad Unipersonal 23/02/2011