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Community register of veterinary medicinal products


Product information

Invented name: Activyl Tick Plus   
Auth. number : EU/2/11/137
Active substance : Indoxacarb + permethrin
ATC: Anatomical main group: QP - Antiparasitic products, insecticides and repellents
Therapeutic subgroup: QP53 - Ectoparaciticides, insecticides and repellents
Pharmacological subgroup: QP53A - Ectoparasiticides for topical use, incl. insecticides
Chemical subgroup: QP53AC - Pyrethrins and pyrethroids
Chemical substance: QP53AC54 - permethrin, combinations
(See WHO ATCvet Index)
Indication: Treatment of flea infestations (Ctenocephalides felis); the product has persistent insecticidal efficacy for up to 4 weeks against Ctenocephalides felis.
The product has persistent acaricidal efficacy for up to 5 weeks against Ixodes ricinus and up to 3 weeks against Rhipicephalus sanguineus. If ticks of these species are present when the product is applied, all the ticks may not be killed within the first 48 hours but they may be killed within a week.
The veterinary medicinal product can be used as part of a treatment strategy for flea allergy dermatitis (FAD).
Developing stages of fleas in the pet’s immediate surroundings are killed following contact with Activyl Tick Plus treated dogs.
One treatment provides repellent (anti-feeding) activity against sand flies (Phlebotomus perniciosus) for up to 3 weeks.
Marketing Authorisation Holder: Intervet International B.V.
Wim de Körverstraat 35, 5831 AN Boxmeer, Nederland
EPAR and active package presentations

Package presentations

Information about presentations can be found in the website of the European Medicines Agency under the section "Product Information".
Likewise, presentations on which there has been a Commission decision are referred in the Summary of Product Characteristics (Annex I to the Commission Decision granting the marketing authorisation) which is available in the Community Register.

European Commission proceduresGoto top of the page

Close date procedure Procedure type EMEA number Decision summary publ decision docs annex
11/01/2012 Centralised - Authorisation EMEA/V/C/2234 (2012)97 of 09/01/2012
30/08/2013 Centralised - Variation EMEA/V/C/2234/IB/2
Updated with Decision(2014)5757 of 05/08/2014
18/07/2014 Centralised - Variation EMEA/V/C/2234/IB/4
Updated with Decision(2014)5757 of 05/08/2014
07/08/2014 Centralised - Yearly update (2014)5757 of 05/08/2014
13/02/2015 Centralised - Variation EMEA/V/C/2234/IB/6
Updated with Decision(2016)1320 of 25/02/2016
29/02/2016 Centralised - Yearly update (2016)1320 of 25/02/2016
16/12/2016 Centralised - Renewal EMEA/V/C/2234/R/9 (2016)8790 of 14/12/2016
30/05/2017 Centralised - 2-Monthly update EMEA/V/C/2234/II/8 (2017)3736 of 24/05/2017