PLASTICISE project – New treatments for stroke, Alzheimer's disease and brain injury
Early results of a European-level project have developed treatments that can restore plasticity in adults back to the level seen in children
Il morbo di Alzheimer e le altre demenze sono tra le principali cause di disabilità per gli anziani. A fronte dell'invecchiamento della popolazione europea, queste malattie costituiscono una priorità d'intervento per la Commissione. A seguito dell'adozione di un'iniziativa europea nel 2009, l'UE sostiene gli sforzi compiuti a livello nazionale per affrontare i principali problemi posti dal morbo di Alzheimer e dalle altre forme di demenza. In particolare, l'iniziativa europea incoraggia lo scambio delle migliori pratiche epidemiologiche, di diagnosi precoce e di cura e assistenza. Mira inoltre a migliorare il coordinamento della ricerca in questo campo.
Iniziativa: Comunicazione della Commissione su una iniziativa europea per il morbo di Alzheimer e le altre forme di demenzaTutte le traduzioni disponibili. ![]()
Ulteriori informazioni sul morbo di Alzheimer e altre demenze:
Early results of a European-level project have developed treatments that can restore plasticity in adults back to the level seen in children
On 30 April, Alzheimer Europe finalised its contribution to the European Commission reflection process on Chronic Diseases.
A report released 11 April 2012 by WHO and ADI calls upon governments, policymakers and other stakeholders to make dementia a global public health priority.
NILVAD is a European multicentre double-blind placebo-controlled phase III trial of nilvadipine in mild to moderate Alzheimer’s disease. It received funding from the European Commission.
EPF report: EPF/FPP Conference under the Polish EU Presidency. A first step into the rights and needs of older patients
Conference will take place in Vienna from 4 to 6 October under the motto "Changing perceptions, practice and policy".
The World's leader academic in the field will discuss new trial designs, animal models, neuroimaging including PET and diagnostic recommendations as well as CSF and blood markers.

Tema principale della conferenza: "Solidarietà europea senza frontiere".
I motivi per cui l'età potrebbe essere un fattore di rischio per le malattie neurodegenerative come il morbo di Alzheimer o di Parkinson sono ancora sconosciuti. Una migliore comprensione delle basi molecolari dell'invecchiamento e delle malattie neurodegenerative potrebbe portare a nuove strategie terapeutiche e preventive.
Which are the new horizons in the comprehension and boosting of human brain capacities?The first day conference will deal with this and with such subjects like creativity, memory and human-machine relationship. The secon day will be dedicated to Alzheimer’s disease.

Gli esperti del settore esamineranno in che modo sono attuati e realizzati concetti quali la prestazione di servizi basati sui risultati e i servizi integrati.
Besides neurodegenerative diseases (e.g. Alzheimer's, Parkinson's) - which have been in the focus of several earlier presidencies as health or "R and D" main themes - the other major set of disorders that have the most profound effect on the population of Europe these days are psychiatric disorders, particularly depression, anxiety and schizophrenia.
La conferenza presenterà una panoramica completa sulle malattie neurodegenerative senza limitarsi al morbo di Alzheimer o di Parkinson.
Alzheimer Europe is organising a lunch debate at the European Parliament in order to discuss the joint programming research in neurogenerative diseases. The area of neurodegenerative diseases, and in particular Alzheimer's disease, has been selected as the first joint programme initiative. The debate at European Parliament wants to get a deeper insight into the development and progress of this European initiative. This is an invitation only meeting.

Le patologie neurodegenerative saranno di nuovo al centro del programma europeo durante la presidenza belga dell'UE. La conferenza fa seguito agli impegni formali assunti a livello di UE per migliorare il trattamento di queste patologie.
Organised under the theme “Facing dementia together”, the conference hopes to explore the partnerships and collaborations necessary to promote a better quality of life for people with dementia and their carers.
This year the conference is in Honolulu on the Hawaiian island of Oahu in the United States.
The theme for World Alzheimer's Day™ 2009 is 'Diagnosing Dementia: See It Sooner'. Every year on 21 September, Alzheimer associations across the globe unite to recognise World Alzheimer's Day in many ways.
Obiettivo del progetto è istituire una rete europea di tutti i soggetti operanti nel campo delle demenze per sviluppare indicatori comuni e alimentare un dialogo continuo al fine di sviluppare sinergie e una più stretta collaborazione a livello europeo.
Early results of a European-level project have developed treatments that can restore plasticity in adults back to the level seen in children
On 30 April, Alzheimer Europe finalised its contribution to the European Commission reflection process on Chronic Diseases.
A report released 11 April 2012 by WHO and ADI calls upon governments, policymakers and other stakeholders to make dementia a global public health priority.
NILVAD is a European multicentre double-blind placebo-controlled phase III trial of nilvadipine in mild to moderate Alzheimer’s disease. It received funding from the European Commission.
EPF report: EPF/FPP Conference under the Polish EU Presidency. A first step into the rights and needs of older patients
Researchers have discovered that there are a number of drugs that give cognitive function a boost.
A new study from University College London, led by Dr. Severine Sabia, shows that men who smoke are more likely to develop dementia later in life.
It will coordinate a major EU research project on neurodegenerative diseases involving 22 countries.
Speech from Máire Geoghegan-Quinn, European Commissioner for Research, Innovation and Science.
Scientists in Finland have discovered how a biochemical signature can potentially predict progression to Alzheimer's disease.

Maximising prospects for successful clinical trials of stem cell therapy for neurodegenerative diseases such as Huntington's and Parkinson's is possible through solid cooperation between experimental and clinical researchers.
Results of an international survey reveal that the majority of respondents in each of the five countries surveyed wish to see government spending increased both on research into treatments for Alzheimer’s disease and caring for people with this condition.

A Belgian-British team of researchers has found a way to design drugs able to target specific areas of the brain.
The study is an outcome of the NOBLESSE ('Nanotechnology, biomaterials and alternative energy source for the European Research Area (ERA))' project.

People in the earliest stages of Alzheimer's disease may be more likely to have a lower body mass index according to a study published in Neurology (Monday 21 November 2011).
Last November the Department of Health set a target to reduce antipsychotic prescriptions to people with dementia by two thirds in a year.
The European Medicines Agency is seeking opinions from the public on a qualification opinion describing a biomarker to help identify patients who can be recruited for clinical trials of treatments for early Alzheimer's disease.

Neuropsychiatric diseases including schizophrenia and bipolar disorder are influenced by epigenetic processes, new research from the United Kingdom shows.
People who rate their health as poor or fair are significantly more likely to develop dementia later in life according to a study published online in Neurology
An international team of researchers partially funded by the EU has uncovered new information linking healthy ageing and neurodegenerative disorders including Alzheimer's disease.

Scientists have moved forward in their understanding of how nerve cells are killed during Alzheimer’s disease, according to research published in the Journal of Neuroscience

Alzheimer's Society’s website has been named as one of the top ten health and medical online sites in 2011.
Every year on 21 September Alzheimer associations across the globe unite to recognise World Alzheimer's Day and 2011 will be no exception with events taking place internationally.
Every year on 21 September on World Alzheimer's Day, sufferers of the condition around the world are honoured and recognised in a drive to push Alzheimer's research to the top of policymaker agendas.
Three-quarters of the estimated 36 million people with dementia worldwide do not have a formal diagnosis, according to a major new report published.
Alzheimer's Society is supporting a new dementia awareness event, Dementia Awareness Day (DAD), which is taking place on Saturday 17 September 2011.
Only one in ten people realise that taking regular exercise is one of the best ways to reduce their risk of developing dementia, according to a survey commissioned by Alzheimer’s Society and Bupa.
The touch screen test - CANTAB - which involves a visual memory test will be trialled by a UK GP Commissioning Board. It will be made available to people aged over 50 who either self-refer to their family doctor, or who are advised to do so by a carer, with suspected Alzheimer's disease.
A higher density of blood vessels in the brain could be an early sign of Alzheimer’s disease according to research published in the Public Library of Science ONE online.
Scientists at The University of Manchester have discovered that measurements of brain activity could be used to predict Alzheimer’s disease in people with mild memory problems.
Norm Mcnamara has written about his experience of living with Alzheimer’s disease in the book entitled “Me and My Alzheimer’s”. Mr McNamara said, “At the age of 50yrs old I was diagnosed with Alzheimers, I am now 53yrs old and have every intention of beating it!!
A study on 100 elderly people with dementia has found that agitated behaviour can be alleviated by group music intervention.
Results of an international survey reveal that over 85% of respondents in the five countries surveyed say that if they were exhibiting confusion and memory loss, they would want to see a doctor to determine if the cause of the symptoms was Alzheimer’s disease.
A hypertension drug could reverse the effects of memory decline.
Three groundbreaking, Alzheimer's Society-supported clinical trials are helping in the fight to reduce the unacceptable levels of inappropriate prescriptions of antipsychotics for people with dementia
Researchers led by the Medical University of Vienna in Austria have identified a new gene called VPS35 that impacts Parkinson's disease.
Results from Europe and U.S. highlight interest in early diagnosis despite wide fear of and familiarity with the condition.
Improving and maintaining health factors not traditionally associated with dementia, such as denture fit, vision and hearing, may lower a person’s risk for developing dementia according to a new study
Alzheimer Europe newsletter covering activities as well as interesting developments in the dementia field in June 2011.
Earlier diagnosis of Alzheimer's disease is one step closer thanks to a team of EU-funded researchers that has developed novel approaches for measuring biomarkers for diagnostics, and a sophisticated system for integrating the information analytically.
Dementia is the most joked about medical condition according to an Alzheimer's Society commissioned poll.

Alzheimer’s Society is calling on amateur and professional photographers to capture what it is like to live with dementia as the charity launches a competition ahead of Dementia Awareness Week.
An extract found in cinnamon bark, called CEppt, contains properties that can delay the development of Alzheimer's disease, according to a study published in the journal PloS One.
Route Map provides the opportunity of a generation to not only transform the face of dementia research but also to transform the lives of hundreds of thousands of people with dementia.
An international team of scientists, funded in part by a European Research Council (ERC) grant under the EU's Seventh Framework Programme (FP7), has discovered a master gene that controls both the lysosomes that break up the debris as well as the cellular compartments that encapsulate the material and fuse with lysosomes to completely dispose of the debris.

Scientists have created an electrical device that can record and play back signals in the brain of rats associated with memory according to a study published in the Journal of Neural Engineering.
The Alzheimer Europe newsletter covering activities as well as interesting developments in the dementia field in May 2011
The Dementia Action Alliance has launched a call to action on the use of antipsychotic drugs for people with dementia.
Within the context of the Seventh Framework Programme (FP7), the European Commission has awarded EUR 6 million to an international research consortium known as NILVAD. The aim of the consortium is to develop a new Alzheimer’s disease treatment.
An international team of researchers has moved forward the development of diagnostic biomarkers for degenerative disorders such as Parkinson's.
Three expert international workgroups convened by the Alzheimer’s Association and the National Institute on Aging (NIA) have issued the first new criteria and guidelines to diagnose Alzheimer’s disease in 27 years.
Brain shrinkage could act as an indicator of Alzheimer’s disease around 10 years before symptoms begin to be seen according to a study published in Neurology.
A group of foundations have launched the ‘Living well with Dementia in the Community Awards’ in order to improve perceptions of dementia and to stimulate solidarity at the local level. The aim of the Initiative is to contribute to a better quality of life for people with dementia and their carers.
Alzheimer’s Society website has been nominated for an award at the prestigious Association of Medical Research Charities’ (AMRC) Science Communication Awards 2011.
At its plenary sitting of 19 January 2011, the European Parliament adopted Marisa Matias’ motion for a resolution on a European initiative to combat Alzheimer’s disease and neurodegenerative disease.
Research led by the University of Leicester in the UK has raised hopes about possible new treatments for devastating neurodegenerative disorders such as Huntington's disease, for which there is currently no cure.
Le cure mediche e sociali per il morbo di Alzheimer costano all'Europa oltre 100 miliardi di euro. Il Parlamento sta esortando i governi UE a dichiarare la demenza una priorità sanitaria per l'Unione europea.
The EU should step up co-operation and support to improve prevention, diagnosis, treatment and care for patients with Alzheimer's disease or other dementias, said Parliament on Wednesday.
People at all stages of Alzheimer’s will now be able to access drugs on the NHS that can slow the progression of the disease.
Several million Europeans suffer from Alzheimer's. Europarltv video explains that MEPs take a stand in favour of more research into the disease in the EU.
Scientists have used a new approach to detect Alzheimer’s disease in the blood according to research published in the journal Cell
Researchers tested the effect of a component of green tea, CAGTE once it had been digested, to see how it affected a key protein in Alzheimer's disease.
High levels of high-density lipoprotein (HDL), or ‘good’ cholesterol, could lessen the chances of developing Alzheimer’s disease in older adults, claims a study.
An international team of scientists has discovered that incomplete memories rather than memory loss is responsible for triggering mental confusion in patients with dementia.
European Parliamentary committee adopts report on a European Initiative on Alzheimer’s disease and other dementias.
This edition of the Health-EU newsletter is dedicated to the high-level conference on dementia that will be held in Brussels on 25-26 November in the context of the Belgian Presidency of the EU.
The aim of the study was to describe the economic impact of dementia in Europe in 2008. The researchers found the total cost of illness of dementia in the EU 27 in 2008 was estimated to be EUR 160 billion.
Forty five organisations from the charity, public and private sectors have come together to form the largest ever united front against dementia.
The findings from the socio-economic impact of dementia workgroup of Alzheimer Europe’s European Collaboration on Dementia (EuroCoDe) project have been published in the peer-reviewed journal, the International Journal of Geriatric Psychiatry.
Walking more than six miles a week could reduce your risk of developing memory problems according to research published in the online issue of Neurology
An editorial in the journal Lancet today (Friday 27 August, 2010) debates the problems of drug development for Alzheimer’s disease.
Researchers in the UK and France are recommending that reducing depression and diabetes, increasing education and eating more fruit and vegetables may reduce the number of people developing dementia.
An early diagnosis of dementia followed by information and support reduces outpatient costs by almost 30 percent, claims new research presented at the International Conference on Alzheimer’s Disease.
Alzheimer Europe reports that at least 5.7 million Europeans, aged between 40 and 80, have Parkinson’s disease or dementia. European researchers are tackling the problem of how people with these diseases can keep their independence and quality of life longer, while safely living in their own homes.
Sono oltre 7 milioni le persone colpite dal morbo di Alzheimer e malattie simili in Europa, e il numero è destinato a raddoppiare nei prossimi 20 anni se non si trovano forme di prevenzione e trattamento adeguato. La Commissione europea propone di mettere in comune le risorse sulla ricerca, per trovare soluzioni comuni a un problema comune a tutti i Paesi europei. Il Parlamento sta preparando un rapporto, curato dall'eurodeputato belga Philippe Lamberts, dei Verdi. Ecco le sue prime riflessioni.
Oggi la Commissione ha adottato proposte concrete per il morbo di Alzheimer e altre forme di demenza e malattie neurodegenerative. Questi problemi sanitari e sociali comuni a tutta l’Europa richiedono un coordinamento per garantire interventi efficaci di prevenzione, diagnosi, trattamento e cura per le persone che ne sono colpite. I paesi europei sono anche invitati a condividere le proprie risorse e a coordinare più efficacemente le attività di ricerca nel settore delle malattie neurodegenerative, in particolare nel caso del morbo di Alzheimer, programmando per la prima volta insieme gli investimenti nella ricerca invece di farlo individualmente. Oggi in Europa sono più di sette milioni le persone colpite dal morbo di Alzheimer e da altre patologie correlate e nei prossimi 20 anni si prevede che questo numero raddoppierà.
This background note provides some examples of research on neurodegenerative diseases supported through the EU's Research Framework Programme.
Il morbo di Alzheimer interessa attualmente 6,1 milioni di europei. Il Parlamento chiede quindi di considerarlo come una priorità in fatto di salute pubblica europea e di definire un piano d'azione europeo. Questo dovrebbe promuovere la ricerca paneuropea sulle cause, la prevenzione e la cura del morbo, migliorare la diagnosi precoce, semplificare e migliorare la qualità di vita dei malati e di chi li assiste, e promuovere il ruolo delle associazioni accordando loro un sostegno regolare.

When dementia strikes, family relationships provide an irreplaceable source of support. The memory goes, but feelings remain. We invited Júlio Machado Vaz, Margarida Pinto Correia, Manuel João Ramos and Fernando Correia to share their families’ experiences.
ESCLUSIVO Basta crederci, essere disperati e pagare. Molto: dai 7 mila ai 36 mila euro. Così «le cliniche della guarigione» promettono cure fasulle per Alzheimer, Parkinson, depressione, sclerosi multipla... Con cellule derivate, in alcuni casi, da feti animali. «Panorama», con casi clinici inventati, si è rivolto a quattro di questi centri. Scoprendo realtà ai limiti dell’incredibile.