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Annex II

LIST OF SUBSTANCES PROHIBITED IN COSMETIC PRODUCTS

Ref. Substance identification
Chemical name / INN CAS Number EC Number
1 N-(5-Chlorobenzoxazol-2-yl)acetamide 35783-57-4 -
2 (2-Acetoxyethyl)trimethylammonium hydroxide (Acetylcholine) and its salts 51-84-3 200-128-9
3 Deanol aceglumate (INN) 3342-61-8 222-085-5
4 Spironolactone (INN) 52-01-7 200-133-6
5 [4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid (Tiratricol (INN)) and its salts 51-24-1 200-086-1
6 Methotrexate (INN) 59-05-2 200-413-8
7 Aminocaproic acid (INN) and its salts 60-32-2 200-469-3
8 Cinchophen (INN), its salts, derivatives and salts of these derivatives 132-60-5 / 5949-18-8 205-067-1 / 227-710-5
9 Thyropropic acid (INN) and its salts 51-26-3 -
10 Trichloroacetic acid 76-03-9 200-927-2
11 Aconitum napellus L. (leaves, roots and galenical preparations) 84603-50-9 283-252-6
12 Aconitine (principal alkaloid of Aconitum napellus L.) and its salts 302-27-2 206-121-7
13 Adonis vernalis L. and its preparations 84649-73-0 283-458-6
14 Epinephrine (INN) 51-43-4 200-098-7
15 Rauwolfia serpentia L., alkaloids and their salts 90106-13-1 290-234-1
16 Alkyne alcohols, their esters, ethers and salts - -
17 Isoprenaline (INN) 7683-59-2 231-687-7
18 Allyl isothiocyanate 57-06-7 200-309-2
19 Alloclamide (INN) and its salts 5486-77-1 -
20 Nalorphine (INN), its salts and ethers 62-67-9 200-546-1
21 Sympathicomimetic amines acting on the central nervous system: any substance contained in the first list of medicaments which are subject to medical prescription and referred to in Resolution AP (69) 2 of the Council of Europe 300-62-9 206-096-2
22 4,4'-Methylene bis(2-chloroaniline) and its salts; 2,2'-Dichloro-4,4'-methylenedianiline and its salts
101-14-4 202-918-9
22 Aniline, its salts and its halogenated and sulphonated derivatives 62-53-3 200-539-3
23 Betoxycaine (INN) and its salts 3818-62-0 -
24 Zoxazolamine (INN) 61-80-3 200-519-4
25 Procainamide (INN), its salts and derivatives 51-06-9 200-078-8
26 Benzidine 92-87-5 202-199-1
27 Tuaminoheptane (INN), its isomers and salts 123-82-0 204-655-5
28 Octodrine (INN) and its salts 543-82-8 208-851-1
29 2-Amino-1,2-bis(4-methoxyphenyl)ethanol and its salts 530-34-7 -
30 1,3-Dimethylpentylamine and its salts 105-41-9 203-296-1
31 4-Aminosalicylic acid and its salts 65-49-6 200-613-5
32 Toluidines, their isomers, salts and halogenated and sulphonated derivatives 26915-12-8 248-105-2
33 Xylidines, their isomers, salts and halogenated and sulphonated derivatives 1300-73-8 215-091-4
34 Imperatorin (9-(3-methylbut-2-enyloxy)furo[3,2-g]chromen-7-one) 482-44-0 207-581-1
35 Ammi majus L. and its galenical preparations 90320-46-0 291-072-4
36 2,3-Dichloro-2-methylbutane 507-45-9 -
37 Substances with androgenic effect
38 Anthracene oil 120-12-7 204-371-1
38 Distillates (coal tar), pitch 101316-49-8 309-855-7
38 Distillates (coal tar), pitch, heavy oils 91995-51-6 295-312-9
38 Distillates (coal tar), pitch, pyrene fraction 91995-52-7 295-313-4
39 Antibiotics
40 Antimony and its compound 7440-36-0 231-146-5
41 Apocynum cannabium L. and its preparations 84603-51-0 283-253-1
42 Apomorphine ((R)-5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol)) and its salts 58-00-4 200-360-0
43 Arsenic acid and its salts 7778-44-1 -
43 Arsenic and its compounds 7440-38-2 231-148-6
44 Atropa belladonna L. and its preparations 8007-93-0 232-365-9
45 Atropine, its salts and derivatives 51-55-8 200-104-8
46 Barium salts, with the exception of barium sulphide under the conditions laid down in Annex III and of barium sulfate, lakes, salts and pigments prepared from the colouring agents when listed in Annex IV
46 Beryllium compounds with the exception of aluminium beryllium silicates 7440-41-7 -
47 Benzene 71-43-2 200-753-7
47 Distillates (petroleum), C7-9, C8-rich, hydrodesulfurized dearomatized, if it contains > 0.1% w/w benzene 101316-56-7 309-862-5
47 Extract residues (coal tar), benzole fraction alk., acid ext., if it contains > 0.1% w/w benzene 101316-63-6 309-868-8
47 Extract residues (coal), light oil alk., acid ext., indene fraction, if it contains > 0.1% w/w benzene 101316-62-5 309-867-2
47 Hydrocarbon oils, arom., mixed with polyethylene and polypropylene, pyrolyzed, light oil fraction, if it contains > 0.1% w/w benzene 100801-63-6 309-745-9
47 Hydrocarbons, C6-8, hydrogenated sorption-dearomatized, toluene raffination, if it contains > 0.1% w/w benzene 101316-66-9 309-870-9
47 Hydrocarbons, C6-rich, hydrotreated light naphtha distillates, solvent-refined, if it contains > 0.1% w/w benzene 101316-67-0 309-871-4
47 Naphtha (petroleum), hydrodesulfurized full-range coker, if it contains > 0.1% w/w benzene 101316-76-1 309-879-8
47 Tar acids, brown-coal, crude, if it contains > 0.1% w/w benzene 101316-86-3 309-888-7
48 Benzimidazol-2(3H)-one 615-16-7 210-412-4
49 Benzazepines and benzodiazepines 12794-10-4 -
50 1-Dimethylaminomethyl-1-methylpropyl benzoate (amylocaine) and its salts 644-26-8 211-411-1
51 2,2,6-Trimethyl-4-piperidyl benzoate (eucaine) and its salts 500-34-5 -
52 Isocarboxazid (INN) 59-63-2 200-438-4
53 Bendroflumethiazide (INN) and its derivatives 73-48-3 200-800-1
54 Beryllium and its compounds 7440-41-7 231-150-7
55 Bromine, elemental 7726-95-6 231-778-1
56 Bretylium tosilate (INN) 61-75-6 200-516-8
57 Carbromal (INN) 77-65-6 201-046-6
58 Bromisoval (INN) 496-67-3 207-825-7
59 Brompheniramine (INN) and its salts 86-22-6 201-657-8
60 Benzilonium bromide (INN) 1050-48-2 213-885-5
61 Tetrylammonium bromide (INN) 71-91-0 200-769-4
62 Brucine 357-57-3 206-614-7
63 Tetracaine (INN) and its salts 94-24-6 202-316-6
64 Mofebutazone (INN) 2210-63-1 218-641-1
65 Tolbutamide (INN) 64-77-7 200-594-3
66 Carbutamide (INN) 339-43-5 206-424-4
67 Phenylbutazone (INN) 50-33-9 200-029-0
68 Cadmium chloride 10108-64-2 233-296-7
68 Cadmium sulphate 10124-36-4 233-331-6
69 Cantharides, Cantharis vesicatoria 92457-17-5 296-298-7
70 Cantharidine 56-25-7 200-263-3
71 Phenprobamate (INN) 673-31-4 211-606-1
72 Nitroderivatives of carbazole
73 Carbon disulphide 75-15-0 200-843-6
74 Catalase 9001-05-2 232-577-1
75 Cephaeline and its salts 483-17-0 207-591-6
76 Chenopodium ambrosioides L. (essential oil) 8006-99-3 -
77 2,2,2-Trichloroethane-1,1-diol 302-17-0 206-117-5
78 Chlorine 7782-50-5 231-959-5
79 Chlorpropamide (INN) 94-20-2 202-314-5
80 Diphenoxylate (INN) hydrochloride 3810-80-8 223-287-6
81 4-Phenylazophenylene-1,3-diamine citrate hydrochloride (Chrysoidine citrate hydrochloride) 5909-04-6 -
82 Chlorzoxazone (INN) 95-25-0 202-403-9
83 2-Chloro-6-methylpyrimidin-4-yldimethylamine (crimidine-ISO) 535-89-7 208-622-6
84 Chlorprothixene (INN) and its salts 113-59-7 204-032-8
85 Clofenamide (INN) 671-95-4 211-588-5