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Job details

Job posted by CNRS UMR 5297 (13/03/2014 17.28)

Post-Doctoral Position Available In cell biology and biophysics

Please note that the job is no longer active!

This project is coordinated by Grégory Giannone (CNRS UMR 5297, Biophysics of Adhesion and Cytoskeleton, Interdisciplinary Institute for NeuroScience, Bordeaux, France). The team of G. Giannone is studying actin and adhesion protein dynamics during cell motility (Cell 2004; Cell 2007) using pioneering optical and biomechanical methods (Biophys J, 2010; Nano Letters 2013; Cell Reports 2013; Nature Cell Biology 2012). Our team will provide an excellent multidisciplinary working environment in the University of Bordeaux, France.

Description

The general goal of our project is to decipher at the molecular level the dynamic and force-modulated interactions between integrins and their regulators within adhesion site (AS). Using super-resolution microscopy and single protein tracking, we recently deciphered the molecular mechanisms of integrin activation within AS (Rossier et al., Nat Cell Biol, 2012). However, to understand the molecular mechanisms controlling the life cycle of AS, it is crucial to study the distribution and dynamics of integrin regulators at the nanoscale level but also their interactions and mechanical responses. We will pursue a multidisciplinary approach combining single protein tracking and super-resolution microscopy, micro-patterned substrates, image analysis and mechanical engineering.

We are seeking a post-doctoral fellow expert in cell biology or optics or mechano-biology.

Nr of positions available : 1

Research Fields

Biological sciences - Biology
Physics - Biophysics

Career Stage

Early stage researcher or 0-4 yrs (Post graduate)

Research Profile

First Stage Researcher (R1)

Benefits

English

Comment/web site for additional job details

The candidate will have a PhD, or equivalent, in a relevant discipline (cell biology, optical imaging or biophysics) with good past-record of achievement and less than 5 years of post-doctoral experience. Physicists having experience with cell biology are encouraged to apply.




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Application e-mail

gregory.giannone@u-bordeaux2.fr

Envisaged Job Starting Date

14/03/2014

Application Deadline

31/10/2014

Other job details
Job ID

33909726

Country

FRANCE

Type of Contract

Temporary

Status

Full-time

Street

146 rue Léo-Saignat

Postal Code

33077

Hours Per Week

40

City

Bordeaux

Company/Institute

CNRS UMR 5297

EU Research Framework Programme
Is the job funded through the EU Research Framework Programme?

No

Company/Institute
CNRS UMR 5297

Institute for Interdisciplinary Neuroscience (IINS)
Public Research
146 rue Léo-Saignat
33077 - Bordeaux
FRANCE
phone 33 5 57 57 57 44
fax 33 5 57 57 40 82
email gregory.giannone@u-bordeaux2.frhttp://www.iins.u-bordeaux2.fr/

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