Postdoctoral position in IIMCB, Warsaw in structural bioinformatics and molecular modeling
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A postdoctoral position funded by an ERC grant “RNA+P=123D” is available to study sequence-structure-function relationships in RNA and RNA-protein complexes in the laboratory of Janusz Bujnicki in the International Institute of Molecular and Cell Biology in Warsaw. Depending on the successful candidate’s background and interests, the work will focus on using existing bioinformatics tools for protein and RNA structure prediction to model structures of various RNA molecules and proteins/complexes involved in RNA metabolism, development of new methods, or a combination of both.
IIMCB (http://iimcb.gov.pl) is the top-ranked (A+) Polish research institute in the field of biology.
The institute provides cutting-edge equipment and facilities, in particular for bioinformatics (e.g. a computing cluster with >1500 cores) and for structural biology (e.g. the X8 PROTEUM X-ray generator with a micro-focus source) as well as for cell biology, neurobiology and imaging.
The Bujnicki group studies sequence-structure-function relationships in proteins and nucleic acids. Our team comprises experimentalists and theoreticians with a very wide area of expertise. We study the naturally occurring systems and infer general rules to develop predictive models and to engineer macromolecules with new functions. We develop computer software, use bioinformatics to make structural and functional predictions, and we test hypotheses in the wet lab. Examples of our successes include the development of software for modeling of protein and RNA structures (e.g. GeneSilico metaserver, ModeRNA), identification and characterization of new enzymes responsible for RNA maturation, and engineering of nucleases with new substrate specificities. See http://iimcb.genesilico.pl for details.
We offer a chance to work in an interdisciplinary laboratory that combines theory and experiment. We use a wide range of techniques, from the development of computational methods for modeling of RNA 3D structure, folding, and dynamics, prediction and design of macromolecular interactions, to experimental research of RNA-protein interactions, and structural analyses of RNA and RNA-protein complexes. All projects involve direct collaboration with bioinformaticians, experimental biochemists, and structural biologists.
Essential qualifications: a PhD in bioinformatics, biology, chemistry, physics, computer science or other relevant field, proven experience in the use of bioinformatics tools for protein and/or RNA structure prediction, and keen interest in structural biology of RNA.
Additional expertise in relevant techniques such as programming, analyses of next generation sequencing data, molecular dynamics, small molecule docking etc. would be an advantage.
All applications should contain a CV, a motivation letter (What do you know about our research? Why do you want to work with us? What are your key strengths? What can you contribute?), and contacts to at least two potential referees, including at least one former or current direct supervisor. Applications will be accepted by email only:
email@example.com and will be collected until a suitable applicant is found
MORE INFORMATION: http://genesilico.pl/employment.html
Please include in your application: "In accordance with the personal data protection act from 29th August 1997, I hereby agree to process and to store my personal data by the Institution for recruitment purposes”.
Nr of positions available : 1
Biological sciences - Biology
Experienced researcher or 4-10 yrs (Post-Doc)
Recognised Researcher (R2)
A fixed basic salary is offered (full time employment, "umowa o prace": 72000 PLN/annum net salary), with possibilities for obtaining additional funding (depending on grant and fellowship applications). The position is available immediately and funding is guaranteed until December 31st 2015.
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International Institute of Molecular and Cell Biology
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