Postdoctoral position in IIMCB, Warsaw in biochemistry of RNA-protein interactions
Please note that the job is no longer active!
A postdoctoral position funded by an ERC grant “RNA+P=123D” is available to study the mechanisms of RNA-protein interaction and recognition in the laboratory of Janusz Bujnicki in the International Institute of Molecular and Cell Biology in Warsaw. The planned research will focus on studying how proteins, in particular enzymes, recognize RNA sequences and structures. Depending on the successful candidate’s background and interests, the work will focus on functional and structural characterization of protein-RNA complexes by molecular, biochemical and biophysical methods, engineering of RNA-binding proteins with new substrate specificities or a combination of both.
IIMCB is the top-ranked (A+) Polish research institute in the field of biology.
The institute provides cutting-edge equipment and facilities, in particular for bioinformatics (e.g. a computing cluster with >1500 cores) and for structural biology (e.g. the X8 PROTEUM X-ray generator with a micro-focus source) as well as for cell biology, neurobiology and imaging.
The Bujnicki group studies sequence-structure-function relationships in proteins and nucleic acids. Our team comprises experimentalists and theoreticians with a very wide area of expertise. We study the naturally occurring systems and infer general rules to develop predictive models and to engineer macromolecules with new functions. We develop computer software, use bioinformatics to make structural and functional predictions, and we test hypotheses in the wet lab. Examples of our successes include the development of software for modeling of protein and RNA structures (e.g. GeneSilico metaserver, ModeRNA), identification and characterization of new enzymes responsible for RNA maturation, and engineering of nucleases with new substrate specificities. See http://iimcb.genesilico.pl for details.
We offer a chance to work in an interdisciplinary laboratory that combines theory and experiment. We use a wide range of techniques, from the development of computational methods for modeling of RNA 3D structure, folding, and dynamics, prediction and design of macromolecular interactions, to experimental research of RNA-protein interactions, and structural analyses of RNA and RNA-protein complexes. All projects involve direct collaboration with bioinformaticians, experimental biochemists, and structural biologists.
Essential qualifications: a PhD in molecular biology or other relevant field, proven experience in experimental research on protein-nucleic acid interactions, and keen interest in RNA biology and/or protein engineering.
Additional expertise in relevant techniques such as high-throughput analyses of nucleic acids (next generation sequencing, RNA-seq, SHAPE, CLIP…), macromolecular crystallography, cell biology, protein engineering etc. would be an advantage.
All applications should contain a CV, a motivation letter (What do you know about our research? Why do you want to work with us? What are your key strengths? What can you contribute?), and contacts to at least two potential referees, including at least one former or current direct supervisor. Applications will be accepted by email only: email@example.com and will be collected until a suitable applicant is found.
MORE INFORMATION: http://genesilico.pl/employment.html
Please include in your application: "In accordance with the personal data protection act from 29th August 1997, I hereby agree to process and to store my personal data by the Institution for recruitment purposes”.
Nr of positions available : 1
Biological sciences - Biology
Experienced researcher or 4-10 yrs (Post-Doc)
Recognised Researcher (R2)
A fixed basic salary is offered (full time employment, "umowa o prace": 72000 PLN/annum net salary), with possibilities for obtaining additional funding (depending on grant and fellowship applications). The position is available immediately and funding is guaranteed until December 31st 2015.
To better plan and organise their stay in a foreign European country, researchers and their families can also benefit of the free and personalised assistance offered by the EURAXESS Services Centres, a network of more than 200 centres located in 40 different European countries.
International Institute of Molecular and Cell Biology
4, Ks. Trojdena
Publish your job vacancies & fellowship programmes or Post your CV