return

Job details

Job posted by Weizmann Institute of Science (03/09/2013 16.24)

Phd research position in the department of Department of Biological Regulation

Please note that the job is no longer active!

Exploring the metabolic function of a novel mitochondrial protein named MTCH2

Description

Phd Research position in the department of Department of Biological Regulation at Weizmann institute of Science in the group of Atan Gross for 4 years. Mitochondrial Carrier Homolog 2 (MTCH2) functions as a receptor-like protein for the pro-apoptotic BID protein, and is essential for BID-induced mitochondria outer-membrane permeabilization (MOMP; Zaltsman et al. Nat Cell Biol 2010). MTCH2 was also identified as one of six new gene loci associated with Body Mass Index (BMI) and obesity in humans suggesting that MTCH2 may also play a role in metabolism. To explore the possible role of MTCH2 in metabolism we generated a MTCH2 liver conditional knockout mouse, a MTCH2 skeletal muscle-conditional knockout mouse, and a brain-conditional KO mouse. We performed metabolic profiling both in vitro and in vivo and the preliminary results are exciting. This position is open to further explore the different initial phenotypes that have arised from these studies.

Nr of positions available : 1

Please note that the full description may be available in the national language since some job boards have their own publication policy. Thank you for your understanding!

Research Fields

Biological sciences

Career Stage

Early stage researcher or 0-4 yrs (Post graduate)
Experienced researcher or 4-10 yrs (Post-Doc)
More Experienced researcher or >10 yrs (Senior)

Research Profiles

Not defined

Benefits

For normal benefits and financial support, please consult the regulations available at http://www.weizmann.ac.il/feinberg/regulations.shtml


Requirements

Required Research Experiences
Main Research Field Biological sciences
Required Languages
Language ENGLISH
Language Level Good
Required Education Level
Degree Field Biological sciences
Required Research Experiences
Years of Research Experience 1
Required Education Level
Degree BSc or MSc
GET MORE! The EURAXESS Services Centres
 

To better plan and organise their stay in a foreign European country, researchers and their families can also benefit of the free and personalised assistance offered by the EURAXESS Services Centres, a network of more than 200 centres located in 40 different European countries.

Other job details
Job ID

33879299

Type of Contract

Temporary

Status

Full-time

Country

ISRAEL

Company/Institute

Weizmann Inst. of Science

City

Rehovot

EU Research Framework Programme
Is the job funded through the EU Research Framework Programme?

No

Company/Institute
Weizmann Institute of Science

Department of Biological Regulation
Other
Herzel St.
76100 - Rehovot
ISRAEL
phone 972 08 9343656
email atan.gross@weizmann.ac.ilhttp://www.weizmann.ac.il/feinberg

QR-Code