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Job details

Job posted by IVIOMICS S.L. (27/03/2013 12.42)

Marie Curie Actions funded job vacancy PhD computational/bioinformatic genomic analyst

  !   Offer by Large Company/SME

Please note that the job is no longer active!

A full time position is available for 2 years, for an experienced computational/bioinformatic genomics analyst to work on the data obtained in a retrospective study on pregnancy rates after ERA diagnosis in embryo implantation failure assisted reproduction seeking patients. Also to work on the diagnostic value of novel gene markers for the ERA test, to optimize complexity of the ERA test minimizing unnecessary gene redundancy and the design and implementation of projects aimed at integrating Next Generation Sequencing (NGS) data in clinical settings. To design, program, and validate class prediction tools based on gene expression microarray profiles and NGS data and to develop bioinformatic tools for genetic and genomic analyses of complex clinical datasets. To assist in the design and statistical data analysis of research projects and randomized controlled trials.
The position is available within a FP7 Industry-Academia Partnerships and Pathways project “SARM” (GA number: 324509).

Description

IVIOMICS is a company that provides advanced services in reproductive genetics. Our broad experience and qualifications make us one of the global leaders in this field.
The SARM consortium consists of 2 industrial and 3 academic partners, forming a strong, stimulating and coherent research environment ensuring the pooling of complementary scientific skills in reproductive genetics and medicine. Infertility is a serious medical concern preventing the parenthood in 10% of couples. Infertility treatment using assisted reproduction techniques (ART) is widely used in Europe with up to 5% of children born thanks to medical help. Despite many technological improvements the overall pregnancy rate after infertility treatment using the most commonly practiced in vitro fertilization (IVF) remains only 30% per single cycle.

A full time position is available for 2 years, for an experienced computational/bioinformatic genomics analyst to work on the data obtained in a retrospective study on pregnancy rates after ERA diagnosis in embryo implantation failure assisted reproduction seeking patients. The ERA diagnosis is based on a custom gene expression microarray that interrogates 238 specific genes. The recruited fellow is to work on the diagnostic value of novel gene markers for the ERA test, to optimize complexity of the ERA test minimizing unnecessary gene redundancy and the design and implementation of projects aimed at integrating Next Generation Sequencing (NGS) data in clinical settings; To design, program, and validate class prediction tools based on gene expression microarray profiles and NGS data and to develop bioinformatic tools for genetic and genomic analyses of complex clinical datasets, utilizing IVIOMICS lab data and public datasets. To assist in the design and statistical data analysis of research projects and randomized controlled trials.

Gross Salary: 56,200 €/year

Nr of positions available : 1

Research Fields

Biological sciences - Biology

Career Stage

Experienced researcher or 4-10 yrs (Post-Doc)

Research Profile

Recognised Researcher (R2)

Benefits

In addition to the Living Allowance, a Mobility Allowance will be paid to eligible researcher, taking due account of the family situation of the researcher and the nature of the activity. Both Living Allowance and Mobility Allowance are based on flat rate contributions.The former includes full social security coverage and the latter is to cover those personal household, relocation and travel expenses associated with undertaking transnational mobility.


Requirements

Required Research Experiences
Main Research Field Biological sciences
Research Sub Field Biology
Required Languages
Language ENGLISH
Language Level Excellent
Required Education Level
Degree Field Biological sciences
Additional Requirements
PhD in bioinformatics, computational genomics, human genetics, statistical genetics or biological science with relevant experience in the other subjects.
Experience and a strong foundation in statistical and quantitative methods.
Several years of professional experience with common programming languages/environments is expected. This includes proved working knowledge of numerical analysis environments (R or pylab), BioConductor, at least one statistical programming environment (preferentially R), one or more general-purpose scripting languages (e.g. Python, C/C++, Perl, Java). Experience with web development frameworks and design, construction and maintenance of databases and relational databases (eg. mySQL).
Experience with designing and programming of class prediction tools based on gene expression microarray and NGS data and on developing bioinformatic tools for genetic and genomic analyses of complex clinical datasets.
Experience with the analysis, interpretation, visualization and management of large and complex genomic datasets generated by microarrays and high throughput sequencing and from protein sequence data. Experience in integration of data from multiple platforms and on functional genomics as well as curating and harmonizing reference data from sources like dbSNP, ENSEMBL, RefGene, HGMD, etc.

The position is available full time since September 2013.
The location of the workplace is in Valencia, Spain.
The candidate must have not resided or carried out his/her main activity in Spain for more than 12 months in the 3 years immediately prior to taking up the currently advertised position.
Start date of the contract: 01 September 2013
Duration: 24 months.

Application procedure:
Applications must be sent electronically in pdf format to Marcos Alepuz(Marcos.Alepuz@ivi.es) and received latest May 30th, 2013. Application package has to consist of:
• CV
•a list of publications
•a letter of interest (2 A4 pages)
•recommendation letter(s) or reference contacts

For additional enquiries about the scope of work please also contact Mr. Marcos Alepuz by e-mail. IVIOMICS might suggest an interview in the process with the best candidates. Application results will be communicated back to applicants by e-mail.
Selection will be made latest by May 31st, 2013.
A strong publication record of bioinformatics research in collaboration with experimental biologists is expected.
The right candidate will have strong organization and communication skills, with demonstrated ability to productively work as a member of a team. Strong verbal and written communication skills in English are required.
The candidate will have a strong interest in analysis of high dimensional biological datasets, gene expression or miRNA analysis, copy number variation, gene-gene and gene-environment interactions, functional validation of SNPs, all of it in clinical and preclinical environment to contribute towards a personalized medicine for infertility patients.
Required Education Level
Degree PhD or equivalent
Required Research Experiences
Years of Research Experience 8
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Application e-mail

marcos.alepuz@ivi.es

Envisaged Job Starting Date

02/12/2013

Application Deadline

01/12/2015

Other job details
Job ID

33845951

Country

SPAIN

Type of Contract

Temporary

Status

Full-time

City

Paterna

Hours Per Week

40

Street

Agustín Escardino, 9. Edifico 3. 2ª Planta

Postal Code

46980

Company/Institute

IVIOMICS S.L.

EU Research Framework Programme
Is the job funded through the EU Research Framework Programme?

FP7/People - Marie Curie Actions

Advert Number

324509

Company/Institute
IVIOMICS S.L.

Product development
Large Company
Agustín Escardino, 9. Edifico 3. 2ª Planta
46980 - Paterna
SPAIN
email marcos.alepuz@ivi.eshttp://www.iviomics.com

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