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Fellowship & Grant details

Fellowship posted by Goethe-University Frankfurt (14/03/2016 15.46)

Marie Curie Actions funded fellowship PhD Fellowship

Project ESR6: UPR as a novel therapeutic target in paediatric cancers
This project will focus on exploring the potential of targeting the UPR in paediatric cancers. ESR6 will screen a large number paediatric cancer cell lines and primary patient material for sensitivity to ER stress inducers to identify childhood cancers that are particularly prone to ER stress. Combinations of ER stress inducers and other cytotoxic drugs will be tested to identify synergistic drug interactions and a synthetic lethality screening assay using a genome-wide shRNA library will be used to discover novel candidate genes that regulate ER stress-triggered cell death in childhood cancers. Candidate genes will be characterized and validated in cell culture and in vivo using the chorioallantois membrane model.

Research Fields

Biological sciences - Biology

Eligibility criteria

Applicants need to fully comply with the three eligibility criteria:
1) Early-stage researchers (ESR) are those who are, at the time of recruitment by the host, in the first four years (full-time equivalent) of their research careers. This is measured from the date when they obtained the degree which formally entitles them to embark on a doctorate, either in the country in which the degree was obtained or in the country in which the research training is provided, irrespective of whether or not a doctorate was envisaged. Please note applicants cannot already hold a PhD.
2) Conditions of international mobility of researchers: Researchers are required to undertake trans-national mobility (i.e. move from one country to another) when taking up the appointment. At the time of selection by the host organisation, researchers must not have resided or carried out their main activity (work, studies, etc.) in Ireland for more than 12 months in the 3 years immediately prior to their recruitment. Short stays, such as holidays, are not taken into account.
3) English language: Network fellows (ESRs) must demonstrate that their ability to understand and express themselves in both written and spoken English is sufficiently high for them to derive the full benefit from the network training.

Selection process

Application procedure:
Applications should include a detailed CV including the contact details of three references and a one page motivation letter describing your research career goals, skills and experience. Please send applications by e-mail (in word or PDF only) to jobs@kinderkrebsstiftung-frankfurt.de by 30 June 2016.
Successful applicants will need to prove that they are eligible (three aspects: respect ESR definition, mobility criteria, and English language proficiency) and will be required to provide transcripts. The selected ESRs are expected to start as soon as possible.


Programme Description
International mobility required ?yes
Eligible destination country/ies for fellowsAlbania, Andorra, Austria, Belarus, Belgium, Bosnia-Herzegovina, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Faroe Islands, Finland, France, FYRoMacedonia, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Liechtenstein, Lithuania, Luxembourg, Malta, MOLDOVA, Monaco, Montenegro, Netherlands, Norway, Poland, Portugal, Romania, Russia, San Marino, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland, Turkey, Ukraine, United Kingdom, Vatican City
Eligibility of fellows: country/ies of residenceAlbania, Andorra, Austria, Belarus, Belgium, Bosnia-Herzegovina, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Faroe Islands, Finland, France, FYRoMacedonia, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Liechtenstein, Lithuania, Malta, MOLDOVA, Monaco, Montenegro, Netherlands, Norway, Poland, Portugal, Romania, Russia, San Marino, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland, Turkey, Ukraine, United Kingdom, Vatican City
Eligibility of fellows: nationality/iesAlbania, Andorra, Austria, Belarus, Belgium, Bosnia-Herzegovina, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Faroe Islands, Finland, France, FYRoMacedonia, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Liechtenstein, Lithuania, Luxembourg, Malta, MOLDOVA, Monaco, Montenegro, Netherlands, Norway, Poland, Portugal, Romania, Russia, San Marino, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland, Turkey, Ukraine, United Kingdom, Vatican City
Fellowship's Details
Career StageEarly stage researcher or 0-4 yrs (Post graduate)
Research ProfilesFirst Stage Researcher (R1)
Employment contract with full social securityyes
Currencyeuro
Covers salaryyes
Covers travel and subsistenceyes
Covers research costsyes
Maximum duration of fellowship48
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Application deadline

30/06/2016

Application e-mail

jobs@kinderkrebsstiftung-frankfurt.de

Other fellowship details
EURAXESS ID

96508

EU Research Framework Programme

H2020

EU Contract Number

H2020-MSCA-ETN -675448

Funding organisation / Contacts
Goethe-University Frankfurt

Academic
Komturstrasse 3a 60528 Frankfurt - Germany
http://www.kinderkrebsstiftung-frankfurt.de/
E-mails
jobs@kinderkrebsstiftung-frankfurt.de

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