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Fellowship & Grant details

Fellowship posted by Italian Ministry of Education, University and Research (24/06/2014 04.01)

Functional study of the role of the PINK1 protein and its interactors in the mechanisms of autophagy, mitophagy and neuronal death

Please note that the job is no longer active!

The project will be focused on the characterization of PINK1, a kinase protein mutated in autosomal recessive Parkinson's disease (PD), known to prevent mitochondrial damage and apoptosis and to regulate mitochondrial dynamics and mitophagy. It is known that PINK1 interacts with Beclin1, positively regulating the autophagy and with Bcl−xL, a key antiapoptotic protein implicated in regulation of mitochondrial homeostasis and synaptic plasticity. The candidate will investigate the functional role of PINK1 interactions on autophagic and apoptotic pathways and will characterize the subcellular sites where this interactions take place, through a range of complementary in vitro and in vivo techniques. Experience in techniques of co-immunoprecipitation, subcellular fractionation and confocal microscopy is especially requested.

Please note that the full description may be available in the national language since some job boards have their own publication policy. Thank you for your understanding!

Research Fields

Neurosciences


Programme Description
Number of awards per year1
International mobility required ?yes
Eligible destination country/ies for fellowsAlbania, Andorra, Austria, Belarus, Belgium, Bosnia-Herzegovina, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Faroe Islands, Finland, France, FYRoMacedonia, Germany, Greece, Hungary, Iceland, Ireland, Italy, Italy, Latvia, Liechtenstein, Lithuania, Luxembourg, Malta, MOLDOVA, Monaco, Montenegro, Netherlands, Norway, Poland, Portugal, Romania, Russia, San Marino, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland, Switzerland, Turkey, Ukraine, United Kingdom, Vatican City
Eligibility of fellows: country/ies of residenceAll
Eligibility of fellows: nationality/iesAll
Website of Fellowship Programmehttp://ww2.unime.it/assric/
Fellowship's Details
Career StageExperienced researcher or 4-10 yrs (Post-Doc)
Research ProfilesNot defined
Employment contract with full social securityno
Total amount per fellowship per year20143
Currencyeuro
Covers salaryyes
Covers travel and subsistenceno
Covers research costsno
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Application deadline

08/07/2014

Other fellowship details
Fellowship ID

71992

Funding organisation / Contacts
Università degli Studi di Messina

Public research
Messina - Italy
www.unime.it
E-mails
sbertino@unime.itPhones
0906768571

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