Fellowship & Grant details

Fellowship posted by Italian Ministry of Education, University and Research (27/03/2014 02.17)

Sequence and structure signatures of resistant mutations in oncogene protein kinases: from bed to bench and back

Please note that the job is no longer active!

Current, advanced studies of PK genes are based on the integration of clinical, genetic/biological, functional, and structural/computational approaches to characterize underlying molecular signatures of cancer mutations. The present research proposal aims at fostergin the existing integrated cancer research workflow among the group MOSE at University of Trieste (UniTS, Italy), the MD Anderson Cancer Center at Houston (TX, USA), the University of Michigan (Ann Arbor, MI, USA), the International Center for Genetic Engineering and Biotechnology (ICGEB, Trieste) and Structural Biology Unit at Elettra-Synchrotron Trieste S.C.p.A. (Italy).

The role of our MOSE computational facility at UniTS will be perform a through in silico structural and energetical characterization of all the detected BCR-ABL single/polymytants and will formulate a rationale for possible mechanisms of PK activation and/or resistance to selected TKIs by said cancer mutations.

Please note that the full description may be available in the national language since some job boards have their own publication policy. Thank you for your understanding!

Research Fields

Biological sciences

Programme Description
Number of awards per year1
Eligible destination country/ies for fellowsAll
Eligibility of fellows: country/ies of residenceAll
Eligibility of fellows: nationality/iesAll
Website of Fellowship
Fellowship's Details
Career StageExperienced researcher or 4-10 yrs (Post-Doc)
Research ProfilesNot defined
Total amount per fellowship per year19367
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Funding organisation / Contacts
Università degli Studi di Trieste

Public research
Trieste - Italy