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Mathematical Modelling of the action of the GoSlo-SR family of BK channel openers using the Horrigan Aldrich Allosteric Model.
The proposed project is aimed primarily at mathematics/physics graduates who wish to ‘discipline-hop’ and use their skills to solve biophysical questions.
We have discovered a novel group of molecules called the GoSlo-SR family, which potently activate a class of ion channels called BK channels. When these membrane pores are opened, they permit K+ ions to leave th...
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