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Anellovirus (AV) are small DNA viruses recently identified in humans and many animals. They are similar to circovirus, that cause important diseases in animal husbandry. In humans, AVs cause acute and chronic infections,; they are widely spread, and are involved in a number of cryptogenic diseases. Furthermore, they are probably able to modulate both innate and adaptive immune responses, thus making infected subjects more susceptible to the effects of other pathogens. The epidemiology of human AVs is little known, but the high prevalence of infections among humans and animals with very similar viruses suggests that interspecies transmission is a common occurrence. The project aims, among other aspects, to detect and quantify the virus in biological samples collected from pigs, using molecular biology methods and analytical protocols already developed and/or pending implementation: the researcher fellow will mainly deal with this aspect of the research.
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