Fellowship & Grant details

Fellowship posted by Italian Ministry of Education, University and Research (04/07/2013 02.21)

Protein and filament mechanics by optical trapping

Please note that the job is no longer active!

This project aims at the application of the dual laser optical tweezers to mechanical studies on single molecules and supramolecular systems involving the contractile and the cytoskeleton proteins of muscle and the membrane proteins responsible for the mechanosensitivity of neurons. A first objective of the research is the development and the characterization of a synthetic biomachine made of a single actin filament brought to interact with an array of myosin motors disposed on a nano-structured inorganic substrate. A second objective is the application of DLOT to the characterization of nociceptor neurons that are constitutively sensitive to mechanical stimulation. In collaboration with the Loboratory of Pharmacology of the Dipartimento Area Critica Medico-Chirurgica we will use neurons in culture to record the mechanical parameters of mechanosensing and its modulation by target molecules

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Research Fields

Biological sciences - Biology

Eligibility criteria

PhD in Physiological Sciences or in Biophysics, minimum four peer reviewed papers on international journals, mimimum two year experience on single molecule mechanics.

Selection process

The competition will be carried out by an evaluation of titles and examination, by means of an interview

Programme Description
Number of awards per year1
Annual budget27000
Frequency of callsannuale
International mobility required ?yes
Eligible destination country/ies for fellowsItaly
Eligibility of fellows: country/ies of residenceAll
Eligibility of fellows: nationality/iesAll
Website of Fellowship Programme
Fellowship's Details
Career StageExperienced researcher or 4-10 yrs (Post-Doc)
Research ProfilesNot defined
Employment contract with full social securityyes
Total amount per fellowship per year27000
Covers salaryyes
Covers travel and subsistenceno
Covers research costsno
Maximum duration of fellowship12
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Application deadline


Other fellowship details


Funding organisation / Contacts
Dipartimento di Biologia - Università degli Studi di Firenze

Public research
Firenze - Italy
055 4572388