Fellowship & Grant details

Fellowship posted by Italian Ministry of Education, University and Research (02/07/2013 03.06)

Immunophenotype and functional studies of dentritic cells in patients with agammaglobulinemia due to mutations of Btk (X-linked type)

Please note that the job is no longer active!

X linked agammaglobulinemia is a primary immunodeficiency characterized by an early block of B cell development due to mutation of the Btk gene. The immunological pattern of these patients is characterized by inability to produce immunoblobulin as a result of the absence of circulating B cells; consequently they suffer from severe and recurrent infections preventable by regular immunoblobulin substitution therapy. However they suffer from infections even during substitution therapy suggesting that btk may influence the biological function of other cells. Our preliminary data suggest that also dendritic cells may be impaired in Btk deficient patients and this topic will be investigated in this research project

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Research Fields

Medical sciences - Medicine

Programme Description
Number of awards per year1
Eligible destination country/ies for fellowsItaly
Eligibility of fellows: country/ies of residenceAll
Eligibility of fellows: nationality/iesAll
Website of Fellowship Programme
Fellowship's Details
Career StageEarly stage researcher or 0-4 yrs (Post graduate)
Research ProfilesNot defined
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Funding organisation / Contacts
Univesrità degli Studi di Brescia

Brescia - Italy