Fellowship & Grant details

Fellowship posted by Italian Ministry of Education, University and Research (02/07/2013 03.05)

Molecular-genetic and immunologic studies of patients affected with Primary Immunodeficiencies and sensorineural hearing loss

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Common Variable Immunodeficiency (CVID) is the most frequent form of PIDs and is characterized by increased susceptibility to infections, autoimmune phaenomea and lymphomas. Besides these clinical manifestations, affected patients tend to develop progressive neurodegeneration, such as sensorineural hearing loss (SNHL), which we first described in CVID. Therefore we propose to study from a molecular/genetic and immunologic point of view more than 70 affected patients in order to define the prevalence of SNHL in CVID, correlate SNHL with B and T cell activations status, and try to identify, if it may exist, a genotype-phenotype correlation between SNHL and candidate genes (such as XBP1, Blimp1 and others)

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Research Fields

Medical sciences - Medicine

Programme Description
Number of awards per year1
Eligible destination country/ies for fellowsItaly
Eligibility of fellows: country/ies of residenceAll
Eligibility of fellows: nationality/iesAll
Website of Fellowship Programme
Fellowship's Details
Career StageEarly stage researcher or 0-4 yrs (Post graduate)
Research ProfilesNot defined
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Funding organisation / Contacts
Università degli Studi di Brescia

Brescia - Italy