Fellowship & Grant details

PhD in UBA-UBX cofactors of the p97 ATPase and their disease-relevant targets

Please note that the job is no longer active!

Recent advances in the field of ubiquitin-dependent degradation indicate that proteasome-mediated degradation requires ubiquitin-receptors that can recognise the ubiquitylated proteins and facilitate their degradation. Among the various ubiquitin-receptors, the p97 ATPase is uniquely endowed with a specialised ATP-dependent segregase activity, which allows it to separate ubiquitylated substrates from cellular structures or from other protein partners.

UBA-UBX proteins are ubiquitin-binding ad...

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Research Fields

Biological sciences

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Programme Description
Eligible destination country/ies for fellowsUnited Kingdom
Eligibility of fellows: country/ies of residenceAll
Eligibility of fellows: nationality/iesAll
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Fellowship's Details
Career StageExperienced researcher or 4-10 yrs (Post-Doc)
Research ProfilesNot defined
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Funding organisation / Contacts
MRC Protein Phosphorylation and Ubiquitylation Unit