Fellowship & Grant details

Fellowship posted by Italian Ministry of Education, University and Research (07/06/2013 04.28)

Anti-angiogenic drugs in ophalmology.

Please note that the job is no longer active!

Neoangiogenesis plays a key role in the pathogenesis of proliferative diabetic retinopathy (PDR). Aim of the treatment of the RDP is to prevent the formation of new vessels or to destroy the existing one. There are currently two different therapeutic approaches that can be used simultaneously or alternately depending on the severity of the pathology: a therapy relies on the use of a laser to destroy the ischemic retinal areas, the other is a drug therapy that provides intra-vitreal injections of antibodies neutralizing anti-VEGF. However the latter approach, in addition to causing side effects to the neuroretina, is not completely resolutive. Recently have been identified numerous other pro-angiogenic molecules released into the extra-cellular (Growth Hormone (GH), Insulin-like growth factor-1 (IGF-1), Angiopoietins, HGF) the presence of which justifies the partial effectiveness of treatment. Hence the need to develop new therapeutic strategies in the broader spectrum.

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Research Fields

Medical sciences

Programme Description
Number of awards per year1
Eligible destination country/ies for fellowsItaly
Eligibility of fellows: country/ies of residenceAll
Eligibility of fellows: nationality/iesAll
Website of Fellowship Programme
Fellowship's Details
Career StageEarly stage researcher or 0-4 yrs (Post graduate)
Research ProfilesNot defined
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Funding organisation / Contacts
Università degli Studi di Brescia

Brescia - Italy