Fellowship & Grant details

Fellowship posted by Italian Ministry of Education, University and Research (25/05/2013 02.04)

Directed evolution of enzymes involved in wine's aroma

Please note that the job is no longer active!

Target of this project is to employ a directed evolution approach aimed at improving cystathionine β-lyase (CBL) catalytic activity toward cysteine-S-conjugates. Directed evolution is a powerful tool for reshaping the functional and structural features of proteins: through iterative cycles of mutation, selection and amplification, important traits of biocatalysts can be optimized for industrial application. We will perform directed evolution of CBL by using error-prone PCR to create a library of variants that will be subsequently screened for improved activity toward cysteine-S-conjugates. Best-performing variant will be sequenced and the mutant enzymes will be expressed and purified.

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Research Fields

Biological sciences

Selection process

The competition will be carried out by an evaluation of titles and examination by means of an interview.

Programme Description
Number of awards per year1
Annual budget22950
International mobility required ?no
Eligible destination country/ies for fellowsItaly
Eligibility of fellows: country/ies of residenceAll
Eligibility of fellows: nationality/iesAll
Website of Fellowship Programme
Fellowship's Details
Career StageEarly stage researcher or 0-4 yrs (Post graduate)
Research ProfilesNot defined
Employment contract with full social securityyes
Total amount per fellowship per year19367
Covers salaryyes
Covers travel and subsistenceno
Covers research costsno
Maximum duration of fellowship21
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Application deadline


Other fellowship details


Funding organisation / Contacts
Università degli Studi di Verona - Dipartimento di Biotecnologie

Public research
Verona - Italy
+ 39 (0) 45 8028204