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In the field of “DNA demethylation, reprogramming and differentiation” the research group of Prof. Christof Niehrs at the Institute of Molecular Biology offers the following PhD project:
Reconstitution of active DNA demethylation
Current knowledge implies DNA repair to be essential for the process of active DNA demethylation in vertebrates. Among several proposed repair mechanisms base excision repair (BER) became generally accepted as a key mechanism for demethylation. BE...
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