Fellowship & Grant details

Fellowship posted by Italian Ministry of Education, University and Research (19/04/2013 02.49)

MIND: Multidisciplinary Investigations for the development of Neuro-protective Drugs

Please note that the job is no longer active!

The requested Post-doc position is funded in the frame of a research project that concerns the development of an innovative therapeutic approach toward the treatment of the Alzheimer’s disease (AD). Specifically, the research to be developed concerns the biological evaluation, with a cellular model, of newly synthesized molecules in relationship with the actvity of chaperones. Will be investigated the effect of perspective drugs on the aggregation of Aβ peptide in a cell culture model, using three relevant cell lines, before and after inhibition of the expression of three of the most important Heat Shock Proteins (Hsp60, Hsp70, and Hsp90), chaperones widely involved in the Alzeheimer’s disease. In order to silence the expression of Hsp60, Hsp70, and Hsp 90 genes, a pool of small interfering RNA oligomers (siRNA) will be used. Moreover will be conducted tests in order to analyze the internalization and the localization of Aβ aggregates in the cell culture models.

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Research Fields

Biological sciences - Biology

Programme Description
Number of awards per year1
International mobility required ?no
Eligible destination country/ies for fellowsItaly
Eligibility of fellows: country/ies of residenceAll
Eligibility of fellows: nationality/iesAll
Website of Fellowship Programme
Fellowship's Details
Career StageEarly stage researcher or 0-4 yrs (Post graduate)
Research ProfilesNot defined
Total amount per fellowship per year19412.56
Covers salaryyes
Covers travel and subsistenceno
Covers research costsno
Maximum duration of fellowship12
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Other fellowship details


Funding organisation / Contacts
Università degli Studi di Palermo

Public research
Palermo - Italy