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The applicant will be working on computational methods for structural bioinformatics. Protein structures can be represented as residue interaction networks (RINs), which consider single amino acids in the protein structure as nodes and connections as physico-chemical interactions. Our group has recently published a novel web server, RING (URL: http://protein.bio.unipd.it/ring/), to construct RINs interactively from PDB structure files for visualization in Cytoscape. This project aims to extend the RING service by assessing sequence evolution and folding energetics, to be implemented as Cytoscape plugins. RINs analyzed with the help of network parameters will provide insights into the existence of common characteristics for these complex systems.
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The selection takes place through the evaluation of the titles, scientific and professional CV, academic/scientific publications and an interview
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