Fellowship & Grant details

Fellowship posted by Italian Ministry of Education, University and Research (03/04/2013 03.24)

Preclinical evaluation of new monoclonal recombinant antibodies

Please note that the job is no longer active!

A number of mAbs have been approved by regulatory agencies for in vivo diagnosis and treatments of cancer. Many of these mAbs display great therapeutic potential by inhibiting cell proliferation or as vehicles for the targeting of radionuclides and cytotoxic agents. The main pitfalls of the use of conventional mAbs in cancer diagnosis and therapy, are the immune response to non-human Abs and the mAbs large size, which impeding penetration into the tumor mass. In this context the human single-chain antibody fragments (scFvs), can be safe, poorly immunogenic, selective and effective diagnostic and therapeutic tools. The aim of this project will be to perform the in vitro and in vivo studies to determine the biological activity of scFvs, pharmacokinetic and biodistribution properties and toxic effects.

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Research Fields

Biological sciences

Programme Description
Number of awards per year1
Eligible destination country/ies for fellowsItaly
Eligibility of fellows: country/ies of residenceAll
Eligibility of fellows: nationality/iesAll
Website of Fellowship
Fellowship's Details
Career StageEarly stage researcher or 0-4 yrs (Post graduate)
Research ProfilesNot defined
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Other fellowship details


Funding organisation / Contacts
Università degli Studi di Urbino Carlo Bo - Dip. di Scienze Biomolecolari

Public research
Urbino - Italy