Fellowship & Grant details

Fellowship posted by Italian Ministry of Education, University and Research (10/03/2013 01.35)

Synthesis and characterization of lipids and liposome formulation to develop lipid based sensors to for the detection of tumour biomarker

Please note that the job is no longer active!

the development of a novel lipid-based sensors for dosing the activity of three specific enzymes that are biomarker of many solid tumours. Lipid vesicles (liposomes) will be designed and formulated in such a way that the interaction of the lipid embedded substrate with the target enzymes (5-fluorouracile, 5-FU) will induce lipid reorganization that will trigger an optical response. The experimental investigations will concern the synthesis of the lipids to be included in liposome formulations and the actual setup of sensors. Various mixed liposomes either using the various types of fluorescent lipids or exploiting non-labelled lipids and including a proper fluorescent probe in the formulation (at the lipid/water interface or in the internal aqueous phase) will be formulated. Lipid composition, fluorescent probe concentration, liposome concentration, kind of buffer and overall concentration conditions will be investigated for observing a proper and highly sensitive optical response.

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Research Fields

Chemistry - Organic chemistry

Programme Description
Number of awards per year1
International mobility required ?yes
Eligible destination country/ies for fellowsItaly
Eligibility of fellows: country/ies of residenceAll
Eligibility of fellows: nationality/iesAll
Website of Fellowship Programmehtpp://
Fellowship's Details
Career StageExperienced researcher or 4-10 yrs (Post-Doc)
Research ProfilesNot defined
Total amount per fellowship per year22946
Covers salaryyes
Covers travel and subsistenceno
Covers research costsno
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Application deadline


Other fellowship details


Funding organisation / Contacts

Public research
L'AQUILA - Italy
0862/433012 - 0862/434242