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Fellowship & Grant details

Fellowship posted by Italian Ministry of Education, University and Research (03/03/2013 03.36)

Role of L-cisteina/H2S transduction pathway in inflammatory disease: identification of a new therapeutic target

Please note that the job is no longer active!

The present project will investigate the role of BARs in regulating CSE and CBS, the two main H2S-generating enzymes, in entero-hepatic tissues and in the cardiovascular system by molecular and pharmacological approaches. Mice deficient for FXR and TGR5 will be characterized for the expression of CSE, CBS and eNOS in the liver, heart, aorta and gastrointestinal tract. Human samples obtained from patients with liver and gastrointestinal disorders will be investigated for CBS and CSE.

Dissecting molecular pathways involved in regulation of CSE and CBS by BARs will be a major step in deciphering the physiology and pathophysiology of H2S and will allow the discovery of novel molecules of potential clinical application in the treatment of liver, gastrointestinal and cardiovascular disorders, including NASH and atherosclerosis, when a modulation of H2S generation could be of therapeutic utility.

Please note that the full description may be available in the national language since some job boards have their own publication policy. Thank you for your understanding!

Research Fields

Medical sciences - Medicine

Eligibility criteria

The Board will evaluate the scientific -professional curriculum, and any other evidence provided which is relevant for the proposed research(eg.Ph.D, Graduate Diploma, post-graduate courses in Italy or abroad, professional qualification obtained through state examinations, documented research at public or private institutions, grants or assignments both in Italy and abroad)

Selection process

The selection evaluates the scientific-professional curriculum and the scientific productivity of the candidate as evident in the documents accompanying the application;it is based on the criteria established by the board, and on the outcomes of an interview in order to assess the suitability of the candidate for the proposed research programm.


Programme Description
Number of awards per year1
Annual budget23.000
Frequency of calls12
International mobility required ?no
Eligible destination country/ies for fellowsItaly
Eligibility of fellows: country/ies of residenceAll
Eligibility of fellows: nationality/iesAll
Website of Fellowship Programmehttp://www.albopretorionline.it/unipg
Fellowship's Details
Career StageEarly stage researcher or 0-4 yrs (Post graduate)
Research ProfileNot defined
Employment contract with full social securityyes
Total amount per fellowship per year23.000
Currencyeuro
Covers salaryyes
Covers travel and subsistenceno
Covers research costsno
Maximum duration of fellowship12
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Application deadline

12/05/2013

Other fellowship details
Fellowship ID

49008

Funding organisation / Contacts
Dipartimento di Medicina Clinica e Sperimentale

Public research
PERUGIA - Italy
http://www.unipg.it
E-mails
dmcs@unipg.itPhones
0755858100

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